Abstract: A peptide is provided with a defined sequence present in the alpha3 chain of the LG4 globule of laminin 332 (laminin 5), and peptides with sequences homologous to the peptide with the defined sequence capable of binding to the syndecan-1 receptor. Pharmaceutical or cosmetic compositions containing the peptide are provided. The peptide is used in the area of tissue healing and regeneration or as an adjuvant in culture media intended for epidermal or epithelial reconstruction. The synthetic peptide comprises the sequence KKLRIKSKEK (SEQ ID NO: 1) or a sequence of identical size, in which the K residue (in position 1) and the R residue (in position 4) are conserved, the sequence being able to bind to the syndecan-1 receptor.
Type:
Grant
Filed:
March 15, 2010
Date of Patent:
February 16, 2016
Assignees:
Symatese, Centre National De La Recherche Scientifique, Universite Claude Bernard Lyon I
Abstract: The present invention concerns an injectable composition comprising a filler or a botulinum toxin and an adrenergic receptor agonist, and its use for diminishing, decreasing or avoiding skin reactions due to injection, specially redness, ecchymosis, bruising, bleeding, erythema, oedema, necrosis, ulceration, swelling and/or inflammation.
Type:
Application
Filed:
May 28, 2010
Publication date:
May 31, 2012
Applicants:
Galderma Research & Development, Symatese
Abstract: Synthetic peptide including the sequence KKLRIKSKEK (SEQ ID 1) or a sequence of identical size, in which the K residue (in position 1) and the R residue (in position 4) are conserved, the sequence being able to bind to the syndecan-1 receptor.
Type:
Application
Filed:
March 15, 2010
Publication date:
May 10, 2012
Applicants:
Symatese, Universite Claude Bernard Lyon I, Centre National De La Recherche Scientifique
Abstract: A lyophilized glue contains a collagen which is partially crosslinked with the aid of at least one type of aldehyde. A method for preparing the glue and the use thereof for producing an adhesive on anti-adhesive prosthesis are also provided.
Abstract: Device designed for regenerating the human dermis presented in the form of a multilayer complex combining an absorbable polymeric internal matrix able to induce the regeneration of the dermis by contact with muscle or subcutaneous tissue, an open-work textile mesh and a transparent external support wherein the open-work textile mesh is contained in the body of the transparent support.