Abstract: This invention describes a non-aqueous oral composition of molecular iodine in a stabilized hydrophobic environment containing a hydrophobe or combination of hydrophobes for treating different disease states.

Abstract: Non-staining topical iodine disinfecting compositions having the ability to inactivate pathogens associated with skin infections or diseases. based upon the presence of molecular iodine in a concentration above at least 15 ppm. Any other iodine species selected from the group consisting of complexed iodine and triiodide may be present with the total of such other iodine species limited to a concentration of less than about 700 ppm so that any visible stain resulting from the application of this composition on the skin will dissipate without leaving any visible skin coloration.

Abstract: Non-staining topical iodine disinfecting compositions having the ability to inactivate pathogens associated with skin infections or diseases. based upon the presence of molecular iodine in a concentration above at least 15 ppm. Any other iodine species selected from the group consisting of complexed iodine and triiodide may be present with the total of such other iodine species limited to a concentration of less than about 700 ppm so that any visible stain resulting from the application of this composition on the skin will dissipate without leaving any visible skin coloration.

Abstract: Non-staining topical iodine disinfecting compositions having the ability to inactivate pathogens associated with skin infections or diseases. based upon the presence of molecular iodine in a concentration above at least 15 ppm. Any other iodine species selected from the group consisting of complexed iodine and triiodide may be present with the total of such other iodine species limited to a concentration of less than about 700 ppm so that any visible stain resulting from the application of this composition on the skin will dissipate without leaving any visible skin coloration.

Abstract: A stabilized solid oral pharmaceutical composition comprised of iodide and iodate as the active agents in the presence of one or more pharmaceutical excipients and a method for preparing these stabilized compositions.

Abstract: A method for forming an iodine disinfecting solution that continuously generates free molecular iodine at a controlled average rate of at least 0.2 ppm per hour over a sustained and extended time period. The method involves combining persulfate anions and iodide anions in sufficient quantity in an aqueous medium having a resulting pH of less than about 6.5 so as to create an iodine generating capacity in said aqueous medium of between 1.5 and 6.5 with a generated concentration of at least 5 ppm of free molecular iodine and maintaining this concentration over the course of the extended time period.

Abstract: The invention is a method of administering therapeutic iodine for treating a disorder in a mammal. The invention comprises a step of feeding said mammal an effective amount of an oxidant for an iodine species and an iodine reductant which will cause oxidation-reduction reactions upon contact with the gastric juices present in the stomach of the mammal. This is done such that molecular iodine is generated in vivo at a ratio of molecular iodine to total iodine of above at least about 0.65. The invention also discloses a non-aqueous pharmaceutically acceptable carrier with said oxidant and reductant having the ability to cause oxidation-reduction reactions upon contact with the gastric juices present in the stomach of said mammal and in an amount sufficient to generate molecular iodine, in vivo, at a ratio of molecular iodine to total iodine of above at least about 0.65.

Abstract: The present invention relates to an enzymatically generated iodine microbicide for the inactivation of pathogenic organisms that are contaminants in or on sensitive biological materials such as the human eye. The biocidal agent from the enzymatic reaction is free molecular iodine which is generated at a minimum level of 5 ppm and comprises at least 25% of the total iodine species present on a molar basis.

Abstract: A microbial decontamination system includes a chamber for housing items to be decontaminated as well as a source of one or more iodine-containing fluids that are conveyed to the chamber as necessary. The system also includes a detector element for monitoring the concentration of free iodine within the chamber. A signal representative of the free iodine concentration is conveyed to a controller element which communicates with receptacles for housing the iodine-containing fluids so that additional iodine-containing fluids may be added to maintain the free iodine concentration within the chamber at a desired level.

Abstract: The present invention relates generally to an enzymatically generated iodine microbiocide and more specifically to the use of such a microbiocide for the inactivation of pathogenic organisms that are contaminants in sensitive biological materials. The biocidal agent from the enzymatic reaction is free molecular iodine generated so as to (1) establish a minimum level above 10 ppm of free molecular iodine and (2) to establish defined ratios of free molecular iodine to other iodine species such that free molecular iodine comprises at least 10% of the total iodine species present on a molar basis.

Abstract: The present invention relates generally to an enzymatically generated iodine microbicide and more specifically to the use of such a microbiocide for the inactivation of pathogenic organisms that are contaminants in or on sensitive biological materials such as the human eye or tissue culture cells. The biocidal agent from the enzymatic reaction is free molecular iodine generated so as to establish a minimum level of 5 ppm in a fashion such that free molecular iodine comprises at least 25% of the total iodine species present on a molar basis.

Abstract: Germicidal iodine based compositions are disclosed that consist of iodide anions, a source of peroxide and peroxidase in combination with iodine sequestering agents. The compositions are formed in situ in an aqueous based medium by combining a peroxide source, iodine ions or source thereof, a peroxidase classified within Enzyme Commission identification No. E.C. 1.11.1.7 and an iodine sequestrant. The addition of a sequestrant before the equilibration of the enzymatic reaction formed by admixing the composition with an aqueous based medium, provides for a non-reactive enzymatic composition. The resulting composition having an increase of available iodine concentration compared to an identical composition without an iodine sequestrant.

Abstract: This invention relates to a method for inactivating pathogens using the peroxidase enzyme. The peroxidase enzyme is reacted with hydrogen peroxide or a source of hydrogen peroxide and an iodide anion to generate reaction products which are separated from the peroxidase enzyme and then used to inactivate pathogenic organisms.

Abstract: This invention relates to a disinfecting epidermal cleaner using peroxidase, peroxide and iodide. The active components are maintained inactive until admixed in a define proportion with water. The pH at which the peroxidase is stored is between 7.0 and 9.0 and the pH of the admixture of the active components is between 3.0 and 6.5.