Patents Assigned to Symetis SA
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Patent number: 10709557Abstract: Embodiments of the present disclosure are directed to stents, valved-stents, (e.g., single-stent-valves and double stent/valved-stent systems) and associated methods and systems for their delivery via minimally-invasive surgery. The stent component comprises a first stent section (102) a second stent section (104) a third stent section (106) and a fourth stent section (108).Type: GrantFiled: February 27, 2019Date of Patent: July 14, 2020Assignee: Symetis SAInventors: Jacques Essinger, Serge Delaloye, Jean-Luc Hefti, Stephane Delaloye
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Publication number: 20200205971Abstract: Apparatus (40) for compressing a transcatheter cardiac stent-valve (10) comprises: a first compressor stage (100) including a hollow channel (42) with a tapered interior surface configured for compressing a stent-valve in response to longitudinal advancement of the stent-valve within the channel; and a second compressor stage (102) comprising a crimper for compressing a portion of the stent-valve without longitudinal advancement.Type: ApplicationFiled: February 26, 2020Publication date: July 2, 2020Applicant: Symetis SAInventors: Luc Mantanus, Fabien Lombardi, Pierre Simonin, Youssef Biadillah, Jean-Luc Hefti, Stephane Delaloye
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Patent number: 10682228Abstract: Apparatus (40) for compressing a transcatheter cardiac stent-valve (10) comprises: a first compressor stage (100) including a hollow channel (42) with a tapered interior surface configured for compressing a stent-valve in response to longitudinal advancement of the stent-valve within the channel; and a second compressor stage (102) comprising a crimper for compressing a portion of the stent-valve without longitudinal advancement.Type: GrantFiled: April 1, 2019Date of Patent: June 16, 2020Assignee: Symetis SAInventors: Luc Mantanus, Fabien Lombardi, Pierre Simonin, Youssef Biadillah, Jean-Luc Hefti, Stephane Delaloye
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Publication number: 20200129293Abstract: A delivery catheter for a stent. The delivery catheter may comprise a distal end and a proximal end. The distal end includes a stent attachment region adapted to receive a stent. The stent may be of the self-expanding type. The catheter further comprises a handle at its proximal end and at least one sheath which may at least partially circumferentially cover said stent such as to retain it in a collapsed configuration. The sheath is coupled at its proximal end to an actuator located on said handle portion.Type: ApplicationFiled: October 31, 2019Publication date: April 30, 2020Applicant: Symetis SAInventors: JACQUES ESSINGER, STEPHANE DELALOYE, JEAN-LUC HEFTI, LUC MANTANUS
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Publication number: 20200069422Abstract: Embodiments of the present disclosure are directed to stents, valved-stents, and associated methods and systems for their delivery via minimally-invasive surgery.Type: ApplicationFiled: July 2, 2019Publication date: March 5, 2020Applicant: Symetis SAInventors: JACQUES ESSINGER, STEPHANE DELALOYE, JEAN-LUC HEFTI, YOUSSEF BIADILLAH, LUC MANTANUS, IKER MALLABIABARRENA, REYNALD PASSERINI, MICHAEL PARIS, FABIEN LOMBARDI
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Publication number: 20200060823Abstract: A delivery catheter for a stent. The delivery catheter may comprise a distal end and a proximal end. The distal end includes a stent attachment region adapted to receive a stent. The stent may be of the self-expanding type. The catheter further comprises a handle at its proximal end and at least one sheath which may at least partially circumferentially cover said stent such as to retain it in a collapsed configuration. The sheath is coupled at its proximal end to an actuator located on said handle portion.Type: ApplicationFiled: October 31, 2019Publication date: February 27, 2020Applicant: Symetis SAInventors: JACQUES ESSINGER, STEPHANE DELALOYE, JEAN-LUC HEFTI, LUC MANTANUS
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Patent number: 10531953Abstract: A delivery apparatus for delivering a stent-valve for implantation within the body, the delivery apparatus configured for introduction into the body through an arterial introducer of a type having a stem insertable into the body and a mouth section that remains outside the body, the mouth section including a haemostasis valve, and wherein the delivery apparatus comprises: a first constraining sheath at a stent-valve accommodation region of the apparatus at a distal end of the apparatus, and configured for constraining at least a portion of a stent-valve at the accommodation region in a radially collapsed configuration; a delivery introducer captive on the delivery apparatus, and slidable between a first position surrounding at least a portion of the stent-valve accommodation region, and a second position in which the delivery introducer slides proximally of the stent-valve accommodation region; wherein the delivery introducer is insertable at least partly into the mouth of a said arterial introducer, the deliType: GrantFiled: October 28, 2014Date of Patent: January 14, 2020Assignee: SYMETIS SAInventors: Fabien Lombardi, Jacques Essinger, Stéphane Delaloye, Jean-Luc Hefti, Luc Mantanus, Youssef Biadillah, Pierre Simonin
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Publication number: 20190336278Abstract: Embodiments of the present disclosure are directed to stents, valved-stents, and associated methods and systems for their delivery via minimally-invasive surgery.Type: ApplicationFiled: July 15, 2019Publication date: November 7, 2019Applicant: Symetis SAInventors: JACQUES ESSINGER, YOUSSEF BIADILLAH, STEPHANE DELALOYE, JEAN-LUC HEFTI, LUC MANTANUS, REYNALD PASSERINI
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Publication number: 20190328514Abstract: Apparatus (40) for compressing a transcatheter cardiac stent-valve (10) comprises: a hollow channel (42) having an interior surface (50) shaped for progressively compressing the stent-valve in response to longitudinal advancement of the stent-valve within the channel; a driver (46) threadedly engaged on the exterior of the channel for generating a longitudinal driving force in response to rotation; a mover (44) having limbs (56) that project through slots (58) in the channel wall to transmit the driving force to the stent-valve within the channel; and a channel extension (48) removably attachable at the exit (54) to provide a generally cylindrical containment bore (66).Type: ApplicationFiled: June 18, 2019Publication date: October 31, 2019Applicant: Symetis SAInventors: Jacques Essinger, Stephane Delaloye, Jean-Luc Hefti, Luc Mantanus, Michael Paris
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Publication number: 20190314151Abstract: A device for heart valve replacement comprises a valve component having at least two valve leaflets preferably made of pericardium tissue. Each valve leaflet includes at least two tabs. The device further includes a stent component configured to be radially compressible into a compressed state and expandable into a functional state. The stent component comprises a first end, a second end and at least one intermediate section arranged between said first and said second end. The intermediate section has at least two commissural posts generally aligned parallel to an axis spanning from the first end to the second end. The commissural posts are formed in the shape of a wishbone.Type: ApplicationFiled: February 11, 2019Publication date: October 17, 2019Applicant: Symetis SAInventors: Youssef Biadillah, Stephane Delaloye, Fabien Lombardi, Jean-Luc Hefti
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Publication number: 20190314153Abstract: Stent-valves (e.g., single-stent-valves and double-stent-valves), associated methods and systems for their delivery via minimally-invasive surgery, and guide-wire compatible closure devices for sealing access orifices are provided.Type: ApplicationFiled: May 24, 2019Publication date: October 17, 2019Applicant: Symetis SAInventors: LUDWIG K. VON SEGESSER, STEPHANE DELALOYE
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Publication number: 20190307560Abstract: Stent-valves (e.g., single-stent-valves and double-stent-valves), associated methods and systems for their delivery via minimally-invasive surgery, and guide-wire compatible closure devices for sealing access orifices are provided.Type: ApplicationFiled: May 21, 2019Publication date: October 10, 2019Applicant: Symetis SAInventors: LUDWIG K. VON SEGESSER, STEPHANE DELALOYE
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Publication number: 20190290427Abstract: Apparatus (40) for compressing a transcatheter cardiac stent-valve (10) comprises: a first compressor stage (100) including a hollow channel (42) with a tapered interior surface configured for compressing a stent-valve in response to longitudinal advancement of the stent-valve within the channel; and a second compressor stage (102) comprising a crimper for compressing a portion of the stent-valve without longitudinal advancement.Type: ApplicationFiled: April 1, 2019Publication date: September 26, 2019Applicant: Symetis SAInventors: Luc Mantanus, Fabien Lombardi, Pierre Simonin, Youssef Biadillah, Jean-Luc Hefti, Stephane Delaloye
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Patent number: 10420658Abstract: Embodiments of the present disclosure are related to devices and techniques for para-valve sealing of an expandable stent-valve implanted using a catheter. In some embodiments, a stent-valve is provided which comprises a seal sleeve/cuff containing material that swells when contacted by blood. A piercing tool may be included and used to permit a user to puncture the sleeve/cuff prior to introduction into a patient's body. In some embodiments, the sleeve/cuff has an integral tubular structure configured to withstand balloon expansion of the stent-valve during or after implantation. In some embodiments, the seal is provided as a separate component from the stent-valve.Type: GrantFiled: March 13, 2014Date of Patent: September 24, 2019Assignee: SYMETIS SAInventors: Stéphane Delaloye, Jacques Essinger, Jean-Luc Hefti, Youssef Biadillah, Luc Mantanus, Fabien Lombardi, Lionel Flaction, Yutit Wanakoht
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Patent number: 10376359Abstract: Embodiments of the present disclosure are directed to stents, valved-stents, and associated methods and systems for their delivery via minimally-invasive surgery.Type: GrantFiled: September 10, 2010Date of Patent: August 13, 2019Assignee: SYMETIS SAInventors: Jacques Essinger, Youssef Biadillah, Stephane Delaloye, Jean-Luc Hefti, Luc Mantanus, Reynald Passerini
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Publication number: 20190231523Abstract: A delivery catheter for a prosthetic heart valve, the valve expandable from a collapsed condition for delivery to an expanded condition for implantation, the delivery catheter comprising: a holder for engaging the valve in the collapsed state of the valve, the holder configured such that (i) in response to a radial compression force exerted thereon, the holder has a first shape defining an exposed engagement region for engaging at least a portion of the collapsed prosthetic heart valve for restraining axial displacement of the prosthetic valve in at least one axial direction of the catheter, and (ii) in response to removal of the radial compression force upon expansion of the valve, at least a portion of the holder transitions to a second shapeType: ApplicationFiled: April 13, 2019Publication date: August 1, 2019Applicant: Symetis SAInventors: Fabien Lombardi, Youssef Biadillah, Jean-Luc Hefti, Luc Mantanus, Stephane Delaoye
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Publication number: 20190216598Abstract: Stent-valves (e.g., single-stent-valves and double-stent-valves), associated methods and systems for their delivery via minimally-invasive surgery, and guide-wire compatible closure devices for sealing access orifices are provided.Type: ApplicationFiled: March 23, 2019Publication date: July 18, 2019Applicant: Symetis SAInventors: LUDWIG K. VON SEGESSER, STEPHANE DELALOYE
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Publication number: 20190201193Abstract: A stent-valve for transcatheter implantation to replace a cardiac valve, the stent valve being compressible to a compressed state for delivery, and expandable to an operative state for implantation, the stent-valve comprising a stent, a plurality of leaflets for defining a prosthetic valve, an inner skirt, an outer skirt, and a paravalve seal for sealing against surrounding tissue. In some embodiments, the paravalve seal comprises material that swells in response to contact with blood. In some embodiments, the seal comprises a flap or pocket that is distensible in response to backpressure and/or paravalve back-flow of blood.Type: ApplicationFiled: March 7, 2019Publication date: July 4, 2019Applicant: Symetis SAInventors: Stephane Delaloye, Jacques Essinger, Jean-Luc Hefti, Youssef Biadillah, Luc Mantanus, Fabien Lombardi
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Patent number: 10335270Abstract: Apparatus (40) for compressing a transcatheter cardiac stent-valve (10) comprises: a hollow channel (42) having an interior surface (50) shaped for progressively compressing the stent-valve in response to longitudinal advancement of the stent-valve within the channel; a driver (46) threadedly engaged on the exterior of the channel for generating a longitudinal driving force in response to rotation; a mover (44) having limbs (56) that project through slots (58) in the channel wall to transmit the driving force to the stent-valve within the channel; and a channel extension (48) removably attachable at the exit (54) to provide a generally cylindrical containment bore (66).Type: GrantFiled: May 3, 2012Date of Patent: July 2, 2019Assignee: SYMETIS SAInventors: Jacques Essinger, Stephane Delaloye, Jean-Luc Hefti, Luc Mantanus, Michael Paris
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Publication number: 20190192291Abstract: Embodiments of the present disclosure are directed to stents, valved-stents, (e.g., single-stent-valves and double stent/valved-stent systems) and associated methods and systems for their delivery via minimally-invasive surgery. The stent component comprises a first stent section (102) a second stent section (104) a third stent section (106) and a fourth stent section (108).Type: ApplicationFiled: February 27, 2019Publication date: June 27, 2019Applicant: Symetis SAInventors: Jacques Essinger, Serge Delaloye, Jean-Luc Hefti, Stephane Delaloye