Patents Assigned to Symphar SA
  • Pharmaceutical aminophosphonic acid derivatives
    Patent number: 6303784
    Abstract: Aminophosphonates alpha substituted by phenol groups, of formula (I) have lipoprotein(a) lowering activity.
    Type: Grant
    Filed: June 18, 1999
    Date of Patent: October 16, 2001
    Assignees: SmithKline Beecham p.l.c., Symphar SA
    Inventors: Lan Mong Nguyen, Hieu Trung Phan, Vinh Van Diep, Simon Floret, Raymond Azoulay, Eric Niesor, Craig Leigh Bentzen, Robert John Ife
  • Compounds and pharmaceutical compositions containing them
    Patent number: 6060464
    Abstract: Aminophosphonates alpha substituted by phenol groups of formula (I) have lipoprotein(a) lowering activity.
    Type: Grant
    Filed: April 3, 1998
    Date of Patent: May 9, 2000
    Assignees: SmithKline Beecham p.l.c., Symphar SA
    Inventors: Lan Mong Nguyen, Eric Niesor, Craig Leigh Bentzen, Hieu Trung Phan, Vinh Van Diep, Simon Floret, Raymond Azoulay, Alexandre Bulla, Yves Guyon-Gellin, Robert John Ife
  • Substituted aminophosphonate derivatives, process for their preparation and pharmaceutical compositions containing them
    Patent number: 5424303
    Abstract: The present invention relates to novel aminophosphonate derivatives substituted in .alpha. position by phenol groups, of formula (I): ##STR1## in which: X.sup.1, X.sup.2, X.sup.3, R.sup.1, R.sup.2, A, B, Z and n are defined in claim 1, as well as their preparations and the pharmaceutical compositions comprising them.
    Type: Grant
    Filed: February 26, 1993
    Date of Patent: June 13, 1995
    Assignee: Symphar SA
    Inventors: Hieu T. Phan, Lan M. Nguyen, Eric Niesor, Yves Guyon-Gellin, Craig L. Bentzen