Patents Assigned to Symvivo Corporation
  • Hybrid proteins and uses thereof
    Patent number: 11236363
    Abstract: There are disclosed hybrid proteins comprising at least one signal sequence; at least one DNA binding domain; and at least one cell penetrating peptide (CPP) domain. In embodiments the CPP domain is a TAT domain, and the DNA binding domain is a HU domain. There is also disclosed the use of the hybrid proteins to introduce exogenous DNA into target cells, and methods for introducing exogenous DNA into target cells using the hybrid proteins.
    Type: Grant
    Filed: August 28, 2019
    Date of Patent: February 1, 2022
    Assignee: Symvivo Corporation
    Inventors: Herbert Alexander Graves, Mark Andrew Fox
  • Hybrid proteins and uses thereof
    Patent number: 10435716
    Abstract: There are disclosed hybrid proteins comprising at least one signal sequence; at least one DNA binding domain; and at least one cell penetrating peptide (CPP) domain. In embodiments the CPP domain is a TAT domain, and the DNA binding domain is a HU domain. There is also disclosed the use of the hybrid proteins to introduce exogenous DNA into target cells, and methods for introducing exogenous DNA into target cells using the hybrid proteins.
    Type: Grant
    Filed: October 20, 2016
    Date of Patent: October 8, 2019
    Assignee: Symvivo Corporation
    Inventors: Herbert Alexander Graves, Mark Andrew Fox
  • Nucleic acid vectors and uses thereof
    Patent number: 10066240
    Abstract: There are disclosed nucleic acid vectors for use in both gram positive and gram negative bacteria. In embodiments the vectors comprise a prokaryotic expression cassette and in embodiments comprise a eukaryotic expression cassette. In embodiments the vectors encode a hybrid protein comprising a DNA binding domain, a CPP domain and a signal sequence.
    Type: Grant
    Filed: February 12, 2015
    Date of Patent: September 4, 2018
    Assignee: Symvivo Corporation
    Inventors: Herbert Alexander Graves, Mark Andrew Fox, Sheetal Raithatha, Umesh Ramachandran