Patents Assigned to Symyx Therapeutics, Inc.
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Publication number: 20050220890Abstract: The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides core-shell compositions and pharmaceutical compositions thereof. Methods of use of the core-shell compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of phosphate imbalance disorders, hypertension, chronic heart failure, end stage renal disease, liver cirrhosis, chronic renal insufficiency, fluid overload, or sodium overload.Type: ApplicationFiled: March 30, 2004Publication date: October 6, 2005Applicant: Symyx Therapeutics, Inc.Inventors: Dominique Charmot, John Fordtran, Han Chang, Eric Connor, Mingjun Liu, Gerrit Klaerner
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Publication number: 20050220889Abstract: The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides core-shell compositions and pharmaceutical compositions thereof. Methods of use of the core-shell compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of phosphate imbalance disorders, hypertension, chronic heart failure, end stage renal disease, liver cirrhosis, chronic renal insufficiency, fluid overload, or sodium overload.Type: ApplicationFiled: March 30, 2004Publication date: October 6, 2005Applicant: Symyx Therapeutics, Inc.Inventors: Dominique Charmot, John Fordtran, Han Chang, Eric Connor, Mingjun Liu, Gerrit Klaerner
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Publication number: 20050220750Abstract: The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides compositions comprising sodium-binding polymers and pharmaceutical compositions thereof. Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of hypertension, chronic heart failure, end stage renal disease, liver cirrhosis, chronic renal insufficiency, fluid overload, or sodium overload.Type: ApplicationFiled: March 30, 2004Publication date: October 6, 2005Applicant: Symyx Therapeutics, Inc.Inventors: Alpern Robert, Jerry Buysse, Han Chang, Dominique Charmot, Michael Cope, John Fordtran, Gerrit Klaerner
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Publication number: 20050209423Abstract: The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides polymeric and pharmaceutical compositions comprising crosslinked amine polymers. Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of renal diseases and hyperphosphatemia.Type: ApplicationFiled: March 22, 2004Publication date: September 22, 2005Applicant: Symyx Therapeutics, Inc.Inventors: Han Chang, Dominique Charmot, Eric Connor, Florence Roger
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Publication number: 20050165190Abstract: The present invention provides polymeric and pharmaceutical compositions comprising a polymer that contains vicinal amine moieties, referred to as polyvicinalamine polymers. The polyvicinalamines can be copolymers or homopolymers. Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of renal diseases, hyperphosphatemia, and the removal of bile acids; oxalates and iron from the gastrointestinal tract.Type: ApplicationFiled: November 3, 2004Publication date: July 28, 2005Applicant: Symyx Therapeutics, Inc.Inventors: Han Ting Chang, Dominique Charmot, Samir Zard
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Publication number: 20050096438Abstract: The present invention provides polymeric and pharmaceutical compositions comprising a polymer that contains vicinal amine moieties, referred to as polyvicinalamine polymers. The polyvicinalamines can be copolymers or homopolymers. Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of renal diseases, hyperphosphatemia, and the removal of bile acids, oxalates and iron from the gastrointestinal tract.Type: ApplicationFiled: November 3, 2003Publication date: May 5, 2005Applicant: Symyx Therapeutics, Inc.Inventors: Han Chang, Dominique Charmot, Samir Zard