Patents Assigned to Syn-Nat Products Enterprise LLC
  • Pharmaceutical co-crystal composition and use thereof
    Patent number: 11685757
    Abstract: The current invention relates to series of co-crystals of platinum analogues and their pharmaceutical use. The co-crystals of the subject invention may be used in the treatment or prevention of cancers and virus infections.
    Type: Grant
    Filed: December 15, 2020
    Date of Patent: June 27, 2023
    Assignee: SYN-NAT PRODUCTS ENTERPRISE LLC
    Inventor: Xiaozhong Liu
  • Composition containing carboplatin and use
    Patent number: 10980768
    Abstract: This invention discloses pharmaceutical use of a dicycloplatin (DCP) for the prophylaxis or treatment of leukemia, renal adenocarcinoma or melanoma. Methods using DCP, either alone or in combination with at least one additional therapeutic agent or adjuvant therapy agent, are also disclosed.
    Type: Grant
    Filed: June 20, 2016
    Date of Patent: April 20, 2021
    Assignee: SYN-NAT PRODUCTS ENTERPRISE LLC
    Inventor: Xiaozhong Liu
  • Pharmaceutical co-crystal and use thereof
    Patent number: 10751318
    Abstract: The current invention relates to a co-crystal of carboplatin with 1,2-cis-cyclobutane dicarboxylate and its pharmaceutical use. The co-crystal of the current invention can be used in the treatment and/or prevention of cancer, as well as the treatment and/or prevention of a virus infection.
    Type: Grant
    Filed: May 17, 2016
    Date of Patent: August 25, 2020
    Assignee: SYN-NAT PRODUCTS ENTERPRISE LLC
    Inventor: Xiaozhong Liu
  • Pharmaceutical co-crystal composition and use thereof
    Patent number: 10428099
    Abstract: The current invention relates to series of co-crystals of platinum analogs and their pharmaceutical use. The co-crystals of the subject invention may be used in the treatment or prevention of cancers and virus infections.
    Type: Grant
    Filed: June 27, 2016
    Date of Patent: October 1, 2019
    Assignee: SYN-NAT PRODUCTS ENTERPRISE LLC
    Inventor: Xiaozhong Liu
  • Pharmaceutical composition of carboplatin based co-crystals and use thereof
    Patent number: 10421770
    Abstract: The current invention relates to series of co-crystals of carboplatin with cyclic amides as co-formers and their pharmaceutical use. The co-crystals of the current invention may be used in the treatment or prevention of cancers.
    Type: Grant
    Filed: June 20, 2016
    Date of Patent: September 24, 2019
    Assignee: SYN-NAT PRODUCTS ENTERPRISE LLC
    Inventor: Xiaozhong Liu
  • Process for the Preparation of Dicycloplatin
    Publication number: 20160297842
    Abstract: The present invention relates to a process to prepare dicycloplatin under mild reactive conditions and at fast reaction rates. The process is reproducible and easy to scale up for industrial application.
    Type: Application
    Filed: April 12, 2016
    Publication date: October 13, 2016
    Applicants: Syn-Nat Products Enterprise LLC, Medoc Pharmaceutical Co., Ltd
    Inventors: Xiaozhong Liu, Jirui Xi, Ye Zhao, Liang Zhang
  • Process for the preparation of dicycloplatin
    Patent number: 9447130
    Abstract: The present invention relates to a process to prepare dicycloplatin under mild reactive conditions and at fast reaction rates. The process is reproducible and easy to scale up for industrial application.
    Type: Grant
    Filed: April 12, 2016
    Date of Patent: September 20, 2016
    Assignees: Syn-Nat Product Enterprise LLC, Medoc Pharmaceutical Co., Ltd.
    Inventors: Xiaozhong Liu, Jirui Xi, Ye Zhao, Liang Zhang