Abstract: An antigen which, as its major immunizing component, comprises a determinant of an adhesin polypeptide or an immunogenically active subsequence thereof or a precursor therefor which is convertible to an immunogenically active form, antibodies against which determinant react with the adhesion polypeptide produced by pathogenic adhesin-forming bacteria which adhere to mammalian tissue, antibodies against such antigen, and DNA expressing, as a principal gene product thereof, such antigen.
Type:
Grant
Filed:
February 19, 1986
Date of Patent:
January 3, 1989
Assignee:
Syn-Tek AB
Inventors:
Frederick C. Lindberg, Bjorn O. Lund, Britt M. Baga, Mari E. Norgren, Mikael Goransson, Bernt E. Uhlin, Jan S. Normark, David L. Lark