Patents Assigned to SYNAPDX CORPORATION
  • Methods and systems for determining autism spectrum disorder risk
    Patent number: 9176113
    Abstract: In certain embodiments, the invention stems from the discovery that analysis of population distribution curves of metabolite levels in blood can be used to facilitate predicting risk of autism spectrum disorder (ASD) and/or to differentiate between ASD and non-ASD developmental delay (DD) in a subject. In certain aspects, information from assessment of the presence, absence, and/or direction (upper or lower) of a tail effect in a metabolite distribution curve is utilized to predict risk of ASD and/or to differentiate between ASD and DD.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: November 3, 2015
    Assignee: SynapDx Corporation
    Inventors: Ute Geigenmuller, Doris Damian, Maciej Pacula, Mark A. DePristo
  • SYSTEMS AND METHODS FOR DISTINGUISHING BETWEEN AUTISM SPECTRUM DISORDERS (ASD) AND NON-ASD DEVELOPMENT DELAY
    Publication number: 20140045702
    Abstract: Methods and systems are presented herein to distinguish children with Autism Spectrum Disorders (ASD) from those with other forms of developmental delay (DD) based on patterns of gene expression levels in blood.
    Type: Application
    Filed: March 15, 2013
    Publication date: February 13, 2014
    Applicant: SynapDx Corporation
    Inventor: SynapDx Corporation
  • SYSTEMS AND METHODS FOR NORMALIZING GENE EXPRESSION PROFILES OF BIOLOGICAL SAMPLES HAVING A MIXED CELL POPULATION
    Publication number: 20140024546
    Abstract: The present disclosure generally provides methods for normalizing gene expression profiles against a cellular repertoire, i.e., the different proportions of various cell types in a sample containing multiple cell types. More specifically, the present disclosure encompasses a method for normalizing the gene expression profile against a mixed cell population.
    Type: Application
    Filed: May 1, 2013
    Publication date: January 23, 2014
    Applicant: SYNAPDX CORPORATION
    Inventor: SYNAPDX CORPORATION