Abstract: Provided herein are methods and dose packs for the monitoring of medication adherence. In one aspect, the dose pack comprises comprise a multiplicity of doses of an agent and a multiplicity of doses of a marker and be configured to isolate a pair of at least one of the multiplicity of doses of the agent and at least one of the multiplicity of doses of the marker for co-administration of the pair to the subject according to the dosing schedule. In another aspect, the method comprises obtaining a sample from the subject subsequent to the conclusion of a monitoring window and analyzing the sample for the presence or absence of a marker or a degradation product thereof.
Type:
Grant
Filed:
October 23, 2018
Date of Patent:
January 12, 2021
Assignee:
Synapse Biosciences, LLC
Inventors:
Robert Anthony Millet, Jr., Philip T. Radford, Ashwin Anand Patkar
Abstract: Provided herein are methods and dose packs for the monitoring of medication adherence. In one aspect, the dose pack comprises comprise a multiplicity of doses of an agent and a multiplicity of doses of a marker and be configured to isolate a pair of at least one of the multiplicity of doses of the agent and at least one of the multiplicity of doses of the marker for co-administration of the pair to the subject according to the dosing schedule. In another aspect, the method comprises obtaining a sample from the subject subsequent to the conclusion of a monitoring window and analyzing the sample for the presence or absence of a marker or a degradation product thereof.
Type:
Application
Filed:
October 23, 2018
Publication date:
February 21, 2019
Applicant:
Synapse Biosciences, LLC
Inventors:
Robert Anthony Millet, JR., Philip T. Radford, Ashwin Anand Patkar
Abstract: Provided herein are methods and dose packs for the monitoring of medication adherence. In one aspect, the dose pack comprises comprise a multiplicity of doses of an agent and a multiplicity of doses of a marker and be configured to isolate a pair of at least one of the multiplicity of doses of the agent and at least one of the multiplicity of doses of the marker for co-administration of the pair to the subject according to the dosing schedule. In another aspect, the method comprises obtaining a sample from the subject subsequent to the conclusion of a monitoring window and analyzing the sample for the presence or absence of a marker or a degradation product thereof.
Type:
Grant
Filed:
May 3, 2017
Date of Patent:
December 4, 2018
Assignee:
Synapse Biosciences, LLC
Inventors:
Robert Anthony Millet, Jr., Philip T. Radford, Ashwin Anand Patkar
Abstract: Provided herein are methods and dose packs for the monitoring of medication adherence. In one aspect, the dose pack comprises comprise a multiplicity of doses of an agent and a multiplicity of doses of a marker and be configured to isolate a pair of at least one of the multiplicity of doses of the agent and at least one of the multiplicity of doses of the marker for co-administration of the pair to the subject according to the dosing schedule. In another aspect, the method comprises obtaining a sample from the subject subsequent to the conclusion of a monitoring window and analyzing the sample for the presence or absence of a marker or a degradation product thereof.
Type:
Application
Filed:
May 3, 2017
Publication date:
November 9, 2017
Applicant:
Synapse Biosciences, LLC
Inventors:
Robert Anthony Millet, JR., Philip T. Radford, Ashwin Anand Patkar