Abstract: Provided are methods for extracting one or more target compounds, such as diterpenes, diterpenoids, triterpenes, and triterpenoids, from a natural biomass using beta-caryophyllene as an extraction solvent. Also provided are compositions comprising beta-caryophyllene, and optionally black cumin seed oil, each independently as a carrier, a delivery adjuvant, a pharmaceutical active ingredient, or any combination thereof; and a diterpene, a diterpenoid, a triterpene, a triterpenoid, or any combination thereof terpenes or triterpenes, including such compositions prepared by the methods herein. Optionally, the compositions further comprise a flavouring agent and/or one or more cannabinoids. Also provided are uses of the pharmaceutical compositions in the treatment of a disease, a disorder or a condition.