Patents Assigned to Sync-Rx, Ltd.
  • Patent number: 8855744
    Abstract: Apparatus and methods are described including, while an endoluminal data-acquisition device is being moved through a subject's lumen, acquiring a plurality of endoluminal data points of the lumen using the endoluminal data-acquisition device. It is determined that respective endoluminal data points correspond to respective locations along the lumen. A display is driven to display at least some of the plurality of endoluminal data points in a stack. While a second endoluminal device is inside the lumen, a current location of at least a portion of the second endoluminal device with respect to the lumen is determined. In response thereto, an image of the second endoluminal device is displayed within the stack, at a location within the stack corresponding to the current location of the second endoluminal device. Other applications are also described.
    Type: Grant
    Filed: December 5, 2013
    Date of Patent: October 7, 2014
    Assignee: Sync-RX, Ltd.
    Inventors: David Tolkowsky, Eldad Klaiman, Alexander Steinberg, Ran Cohen
  • Patent number: 8781193
    Abstract: Apparatus and methods are described for use with an image of blood vessels of a subject. In response to a user designating a single point on the image (a) a target portion of a blood vessel is automatically identified in the vicinity of the designated point, and (b) quantitative vessel analysis is performed on the target portion of the blood vessel. An output is generated based upon the quantitative vessel analysis. Other embodiments are also described.
    Type: Grant
    Filed: November 18, 2009
    Date of Patent: July 15, 2014
    Assignee: Sync-RX, Ltd.
    Inventors: Alexander Steinberg, Sagiv Philipp, David Tolkowsky, Ran Cohen
  • Publication number: 20140161331
    Abstract: Apparatus and methods are described including designating within an image of blood vessels of a subject, a target portion of the blood vessels. In response to a first input from a user that designates a single point on the image, a first location within the blood vessels in a vicinity of the designated point is designated. In response to second and third inputs from the user, proximal and distal locations within the target portion are designated. The target portion is designated such that the target portion passes from the proximal location of the target portion to the distal location of the target portion, and such that the target portion includes the first location. Quantitative vessel analysis is performed on the target portion of the blood vessels, and an output is generated based upon the quantitative vessel analysis. Other applications are also described.
    Type: Application
    Filed: December 31, 2013
    Publication date: June 12, 2014
    Applicant: SYNC-RX, LTD.
    Inventors: Ran COHEN, Eldad KLAIMAN, Alexander STEINBERG, Yoav STEIN, Sagiv PHILIPP, David TOLKOWSKY
  • Publication number: 20140140597
    Abstract: Apparatus and methods are described for use with an input angiogram image of a device inserted inside a portion of subject's body, the angiogram image being acquired in the presence of contrast agent. At least one processor (11) includes background-image-generation functionality (13) configured to generate a background image in which a relative value is assigned to a first pixel with respect to a second pixel, at least partially based upon relative values of surroundings of the first pixel and the surroundings of the second pixel in the input image. Cleaned-image-generation functionality (14) generates a cleaned image in which visibility of the radiopaque portions of the device is increased relative to the input image, by dividing the input image by the background image. Output-generation functionality (15) drives a display (16) to display an output based upon the cleaned image. Other applications are also described.
    Type: Application
    Filed: June 21, 2012
    Publication date: May 22, 2014
    Applicant: SYNC-RX, LTD.
    Inventors: Zohar Barzelay, Ran Cohen, David Tolkowsky
  • Publication number: 20140121513
    Abstract: Apparatus and methods are described for use with a plurality of angiographic image frames of a moving lumen of a subject, including aligning the image frames with each other. Using the aligned image frames, a time it takes a contrast agent to travel a known distance through the lumen is determined. At least partially in response thereto, a characteristic of the lumen is determined, and, in response to the determined characteristic, an output is generated on a display. Other applications are also described.
    Type: Application
    Filed: December 27, 2013
    Publication date: May 1, 2014
    Applicant: SYNC-RX, LTD.
    Inventors: David TOLKOWSKY, Alexander STEINBERG, Eldad KLAIMAN, Ran COHEN
  • Publication number: 20140114308
    Abstract: Apparatus and methods are described for use with a portion of a subject's body that moves as a result of cyclic activity, including sensing a phase of the cyclic activity. In a first cycle of the activity, in response to sensing that the activity is at a given phase, a therapeutic tool is actuated to apply a treatment to the portion by applying energy to the portion. Following the given phase in the first cycle and prior to an occurrence of the given phase in a subsequent cycle, the tool is inhibited from applying energy to the portion. In a second cycle of the activity, subsequent to the inhibiting of the application of energy to the portion, and in response to sensing that the second cycle is at the given phase, the tool is actuated to apply energy to the portion. Other applications are also described.
    Type: Application
    Filed: December 30, 2013
    Publication date: April 24, 2014
    Applicant: SYNC-RX, LTD.
    Inventors: David TOLKOWSKY, Gavriel IDDAN
  • Publication number: 20140114185
    Abstract: Apparatus and methods for use with a set of angiographic images of a lumen of a subject's body are described. Temporal changes in a density of a contrast agent at a given location within the lumen are analyzed via image processing. In response to the analysis, a characteristic of the lumen at the location is determined, and, in response thereto, an output is generated. Other applications are also described.
    Type: Application
    Filed: December 27, 2013
    Publication date: April 24, 2014
    Applicant: SYNC-RX, LTD.
    Inventors: David TOLKOWSKY, Alexander STEINBERG, Eldad KLAIMAN, Ran COHEN
  • Publication number: 20140112566
    Abstract: Apparatus and methods are described including acquiring a plurality of image frames of a blood vessel of a subject, acquisition of the image frames commencing prior to injection of a contrast agent into the blood vessel. A first image frame is identified as being the image frame in which an angiographic sequence commenced by calculating a vesselness descriptor for each one of the image frames, by determining an extent to which pixels within the image frame are likely to correspond to the blood vessel, and by determining that, in the first image frame, there was an increase in the vesselness descriptor relative to at least one image frame acquired prior to the first image frame. An output is generated at least partially in response to identifying the first image frame. Other applications are also described.
    Type: Application
    Filed: December 30, 2013
    Publication date: April 24, 2014
    Applicant: SYNC-RX, LTD.
    Inventors: Alexander STEINBERG, Ran COHEN, Sagiv PHILIPP, David TOLKOWSKY, Eldad KLAIMAN
  • Publication number: 20140111541
    Abstract: Apparatus and methods are described for use with a portion of a body of a subject including acquiring a plurality of images of the portion, and displaying one of the images. In response to receiving an input that is indicative of a given location within the image, an indication of a region within the portion is generated on the image. In response to receiving a further input, a dimension of the region that is indicated within the image is modified. In response thereto, at least one tool that is suitable for being placed at the region is identified, and/or a dimension of at least one tool that is suitable for being placed at the region is identified. An output is generated is response to the identification. Other applications are also described.
    Type: Application
    Filed: December 30, 2013
    Publication date: April 24, 2014
    Applicant: SYNC-RX, LTD.
    Inventors: David TOLKOWSKY, Gavriel IDDAN, Ran COHEN
  • Publication number: 20140114184
    Abstract: Apparatus and methods are described for use with an imaging device (12) configured to acquire a set of angiographic images of a lumen. At least one processor (10) determines blood velocity within the lumen, via image processing. The processor determines a value of a flow-related parameter at the location based upon the determined blood velocity. The processor additionally receives an indication of a value of a second flow-related parameter of the subject, and determines a value of a luminal-flow-related index of the subject at the location, by determining a relationship between the value of the current flow-related parameter and the value of the second flow-related parameter. Other applications are also described.
    Type: Application
    Filed: December 27, 2013
    Publication date: April 24, 2014
    Applicant: SYNC-RX, LTD.
    Inventors: Eldad KLAIMAN, Ran COHEN, David TOLKOWSKY, Alexander STEINBERG
  • Publication number: 20140112539
    Abstract: Apparatus and methods are described for imaging a portion of a body of a subject that undergoes a motion cycle, including acquiring a plurality of image frames of the portion of the subject's body. A given feature is identified in at least some of the image frames. At least some image frames are image tracked with respect to the feature, and the image frames that have been image tracked with respect to the given feature are displayed as a stream of image frames. Visibility of a periphery of the displayed stream of image frames is at least partially reduced. Other applications are also described.
    Type: Application
    Filed: December 30, 2013
    Publication date: April 24, 2014
    Applicant: SYNC-RX, LTD.
    Inventors: David TOLKOWSKY, Ran COHEN, Alexander STEINBERG, Sagiv PHILIPP, Eldad KLAIMAN
  • Publication number: 20140114333
    Abstract: Apparatus and methods are described including sensing a phase of a cyclic activity of a subject. In a first cycle of the cyclic activity, at a given phase of the cycle, movement of a distal portion of a tool toward an occlusion in the subject's blood vessel is allowed. Following the given phase in the first cycle, and prior to an occurrence of the given phase in a subsequent cycle, movement of the tool is inhibited. In a second cycle of the cyclic activity, at the given phase of the cycle, the occlusion is at least partially penetrated by the tool, by allowing movement of the distal portion of the tool through at least a portion of the occlusion. Other applications are also described.
    Type: Application
    Filed: December 30, 2013
    Publication date: April 24, 2014
    Applicant: SYNC-RX, LTD.
    Inventors: David TOLKOWSKY, Gavriel IDDAN
  • Publication number: 20140107479
    Abstract: Apparatus and methods are described for use with a lumen including, without generating a virtual three-dimensional model of the lumen, and by performing image processing on two-dimensional angiographic images, determining blood velocity within the lumen, and determining geometry of the lumen at a given location. A value of a current flow-related parameter at the location is determined based upon the determined blood velocity and the geometry of the lumen at the location. An indication of a value of a second flow-related parameter of the subject is received, and a value of a luminal-flow-related index of the subject at the location is determined, by determining a relationship between the value of the current flow-related parameter and the value of the second flow-related parameter. Other applications are also described.
    Type: Application
    Filed: December 17, 2013
    Publication date: April 17, 2014
    Applicant: SYNC-RX, LTD.
    Inventors: Eldad KLAIMAN, Alexander STEINBERG, Ran COHEN, David TOLKOWSKY
  • Patent number: 8700130
    Abstract: Apparatus is provided, including a sensor for sensing a phase of cyclic activity of a subject's body system. A tool modulator includes a gate configured: in a first cycle of the cyclic activity, to allow movement of a tool, in response to the cyclic activity being at a first given phase thereof, following the given phase in the first cycle and prior to an occurrence of the given phase in a subsequent cycle of the cyclic activity, to inhibit the movement of the tool, and in a second cycle of the cyclic activity, subsequent to the inhibiting of the movement, to allow movement of the tool, in response to the second cycle of the cyclic activity being at the given phase thereof. An accumulation facilitator facilitates an accumulation of the tool in the tool modulator, and/or an accumulation of energy in the tool.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: April 15, 2014
    Assignee: Sync-RX, Ltd.
    Inventors: Gavriel Iddan, David Tolkowsky, Ran Cohen, Jacob Blank
  • Publication number: 20140100451
    Abstract: Apparatus and methods are described for use with an endoluminal data-acquisition device configured to be moved through a lumen of a subject's body, and a two-dimensional angiographic image of the lumen. A value of a luminal-flow-related index of the subject is determined non-invasively at a plurality of locations along the lumen, at least partially by performing image processing on the angiographic image. While the endoluminal data-acquisition device is being moved through the lumen, a set of endoluminal data points of the lumen at a plurality of locations within the lumen is acquired, using the endoluminal data-acquisition device. It is determined that respective endoluminal data points correspond to respective locations along the lumen, and, in response thereto, it is determined that respective endoluminal data points correspond to respective values of the luminal flow-related index. Other applications are also described.
    Type: Application
    Filed: December 17, 2013
    Publication date: April 10, 2014
    Applicant: SYNC-RX, LTD.
    Inventors: David TOLKOWSKY, Ran COHEN, Alexander STEINBERG, Eldad KLAIMAN
  • Patent number: 8693756
    Abstract: Apparatus and methods are described for imaging a portion of a body of a subject that undergoes a motion cycle. A plurality of image frames of the portion are acquired. The image frames are enhanced with respect to a first given feature of the image frames, by (a) image tracking the image frames with respect to the first given feature, (b) identifying a second given feature in each of the image frames, and (c) in response to the identifying, reducing visibility of the second given feature in the image frames. The image frames that (a) have been image tracked with respect to the first given feature, and (b) have had reduced therein the visibility of the second given feature, are displayed as a stream of image frames. Other embodiments are also described.
    Type: Grant
    Filed: August 13, 2013
    Date of Patent: April 8, 2014
    Assignee: Sync-Rx, Ltd.
    Inventors: David Tolkowsky, Ran Cohen, Alexander Steinberg, Sagiv Philipp, Eldad Klaiman
  • Publication number: 20140094660
    Abstract: Apparatus and methods are provided including, while an endoluminal data-acquisition device is being moved through a lumen of a subject, acquiring a plurality of endoluminal data points of the lumen using the endoluminal data-acquisition device. At at least one location it is determined that an event occurred, the event causing the endoluminal data-acquisition device not to acquire a single endoluminal data point at the location. The endoluminal data points are displayed in a stack, in which the endoluminal data points are positioned at locations corresponding to relative locations within the lumen at which the endoluminal data points were acquired, and in which the event is accounted for. Other applications are also described.
    Type: Application
    Filed: December 5, 2013
    Publication date: April 3, 2014
    Applicant: SYNC-RX, LTD.
    Inventors: David TOLKOWSKY, Ran COHEN, Eldad KLAIMAN, Alexander STEINBERG, Zohar BARZELAY
  • Publication number: 20140094689
    Abstract: Apparatus and methods are described including acquiring a first set of extraluminal images of a lumen, using an extraluminal imaging device. At least one of the first set of images is designated as a roadmap image. While an endoluminal device is being moved through the lumen, a second set of extraluminal images is acquired. A plurality of features that are visible within images belonging to the second set of extraluminal images are identified. In response to the identified features in the images belonging to the second set of extraluminal images, a plurality of local calibration factors associated with respective portions of the roadmap image are determined. Other applications are also described.
    Type: Application
    Filed: December 4, 2013
    Publication date: April 3, 2014
    Applicant: SYNC-RX, LTD.
    Inventors: Ran COHEN, Eldad KLAIMAN, Alexander STEINBERG, David TOLKOWSKY
  • Publication number: 20140094693
    Abstract: Apparatus and methods are described including, while an endoluminal data-acquisition device is being moved through a lumen of a subject, acquiring a plurality of endoluminal data points of the lumen using the endoluminal data-acquisition device. It is determined that, at at least one location, no endoluminal data point was acquired. An output is generated using at least a portion of the plurality of endoluminal data points of the lumen acquired using the endoluminal data-acquisition device, the output including an indication that no endoluminal data point was acquired at the location. Other applications are also described.
    Type: Application
    Filed: December 5, 2013
    Publication date: April 3, 2014
    Applicant: SYNC-RX, LTD.
    Inventors: Ran COHEN, Eldad KLAIMAN, Alexander STEINBERG, David TOLKOWSKY
  • Publication number: 20140094691
    Abstract: Apparatus and methods are described including a processor (20) configured to receive first and second sets of extraluminal images of a lumen, the second set being acquired while an endoluminal device is being moved through the lumen. The processor designates at least one of the first set of images as a roadmap image, and designates, within the lumen in the roadmap image, a roadmap pathway (42). A plurality of features (44, 46, 48, 50) that are visible within at least some of the second set of extraluminal images are identified, and an arrangement of three or more of the features within the image are compared to a shape of at least a portion of the roadmap pathway. Based upon the comparing, the identified features are mapped to locations along the roadmap pathway within the roadmap image. Other applications are also described.
    Type: Application
    Filed: December 5, 2013
    Publication date: April 3, 2014
    Applicant: SYNC-RX, LTD.
    Inventors: Alexander STEINBERG, Eldad KLAIMAN, Zohar BARZELAY, Ran COHEN, David TOLKOWSKY