Patents Assigned to Synchronicity
  • Carbazole-containing sulfonamides as cryptochrome modulators
    Patent number: 10383880
    Abstract: The subject matter herein is directed to carbazole-containing sulfonamide derivatives and pharmaceutically acceptable salts or hydrates thereof of structural formula I wherein the variable R1, R2, R3, R4, R5, R6, R7, A, B, C?, D, E, F, G, H?, a, and b are accordingly described. Also provided are pharmaceutical compositions comprising the compounds of formula I to treat a Cry-mediated disease or disorder, such as diabetes, obesity, metabolic syndrome, Cushing's syndrome, and glaucoma.
    Type: Grant
    Filed: September 22, 2017
    Date of Patent: August 20, 2019
    Assignee: Synchronicity
    Inventors: Ross Bersot, Paul Humphries