Patents Assigned to Synchronicity Pharma, Inc.
  • Carbazole-containing amides, carbamates, and ureas as cryptochrome modulators
    Patent number: 10759777
    Abstract: The subject matter herein is directed to carbazole-containing amide, carbamate, and urea derivatives and pharmaceutically acceptable salts or hydrates thereof of structural formula I wherein the variable R1, R2, R3, R4, R5, R6, R7, A, D, E, G, J, L, M, Q, a, and b are accordingly described. Also provided are pharmaceutical compositions containing the compounds of formula I to treat a Cry-mediated disease or disorder, such as diabetes, complications associated with diabetes, Cushing's syndrome, NASH, NAFLD, asthma, and COPD.
    Type: Grant
    Filed: December 27, 2018
    Date of Patent: September 1, 2020
    Assignee: Synchronicity Pharma, Inc.
    Inventors: Ross Bersot, Paul Humphries