Patents Assigned to SyneCor, LLC
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Patent number: 7840282Abstract: A retention device for anchoring a medical device within the vasculature is described. The device may include expandable member coupled to an intravascular medical device and proportioned for receipt within a vessel. At least a portion of the expandable member is expandable to radially engage a vessel wall and to thereby retain the medical device within the vessel. The system is suitable for a variety of intravascular devices, including but not limited to ICD's, pacemakers, and intravascular drug delivery systems.Type: GrantFiled: July 20, 2009Date of Patent: November 23, 2010Assignee: Synecor LLCInventors: Michael S. Williams, Terrance Ransbury, Richard A. Glenn, Kevin Holbrook
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Patent number: 7747335Abstract: Methods and apparatus for implanting a medical device within a living body. The apparatus includes an elongate sleeve positionable with a living body, such as within a blood vessel, and a medical device insertable into the sleeve. During use, the sleeve is retained within the body, and the medical device is sealed within the sleeve. The sleeve substantially avoids biological growth onto the medical device, and thus permits removal of the medical device independently of the sleeve.Type: GrantFiled: December 10, 2004Date of Patent: June 29, 2010Assignee: Synecor LLCInventor: Michael S. Williams
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Patent number: 7734343Abstract: The present application describes an intravascular implantable pacing and/or defibrillation system. The described system includes a pulse generator that is implantable within a blood vessel and proportioned to blood flow through the blood vessel, and at least one lead attachable to the pulse generator. During implantation, the pulse generator is introduced into a patient's vasculature, advanced to a desired vessel and anchored in place within the vessel. The lead or leads are placed within the heart or surrounding vessels as needed to deliver electrical pulses to the appropriate location.Type: GrantFiled: May 31, 2006Date of Patent: June 8, 2010Assignee: Synecor, LLCInventors: Terrance Ransbury, Michael S. Williams
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Patent number: 7704276Abstract: A woven tubular endoprosthesis comprising means for locking the endoprosthesis in a deployed configuration is disclosed. The means for locking the endoprosthesis may comprise locking protrusions, notches, a chemical bond, a curable bond, or other mechanism. The woven fibers comprising the endoprosthesis may be hollow and comprise circumferentially oriented polymeric chains, and may be filled with a curable material. A method of treatment using an endoprosthesis according to the invention is also disclosed.Type: GrantFiled: September 30, 2006Date of Patent: April 27, 2010Assignee: SyneCor, LLCInventors: Michael S. Williams, Richard A. Glenn, Jeffrey A. Smith, Kevin D. Holbrook, Joseph M. DeSimone
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Patent number: 7617007Abstract: The present application describes a retention device for anchoring a medical device within the vasculature. The device may include expandable member coupled to an intravascular medical device and proportioned for receipt within a vessel. At least a portion of the expandable member is expandable to radially engage a vessel wall and to thereby retain the medical device within the vessel. The system is suitable for a variety of intravascular devices, including but not limited to ICD's, pacemakers, and intravascular drug delivery systems.Type: GrantFiled: October 29, 2004Date of Patent: November 10, 2009Assignee: Synecor LLCInventors: Michael S. Williams, Terrance Ransbury, Richard A. Glenn, Kevin Holbrook
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Patent number: 7529589Abstract: The present application describes an intravascular implantable pacing and/or defibrillation system. The described system includes a pulse generator that is implantable within a blood vessel and proportioned to blood flow through the blood vessel, and at least one electrode attachable to the pulse generator. During implantation, the pulse generator is introduced into a patient's vasculature, advanced to a desired vessel and anchored in place within the vessel. The electrode or electrodes are placed within the heart or surrounding vessels as needed to deliver electrical pulses to the appropriate location.Type: GrantFiled: June 4, 2004Date of Patent: May 5, 2009Assignee: Synecor LLCInventors: Michael S. Williams, Terrance Ransbury, Richard A. Glenn, Daniel W. Fifer, Kevin Holbrook
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Publication number: 20090105823Abstract: Devices and methods for manufacturing devices for treating degenerated and/or traumatized intervertebral discs are disclosed. Artificial discs and components of discs may include an artificial nucleus and/or an artificial annulus and may be comprised of shape memory materials synthesized to achieve desired mechanical and physical properties. An artificial nucleus and/or annulus according to the invention may comprise a filler retention membrane that may be filled with a curable material for deployment. A filler retention membrane according to the invention may comprise one or more partitions to define one or more chambers and may comprise one or more valves for selectively permitting the flow of material within the nuclear region and annular region of the filler retention membrane.Type: ApplicationFiled: September 30, 2005Publication date: April 23, 2009Applicant: SYNECOR, LLCInventors: Michael S. Williams, Jeffrey A. Smith
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Patent number: 7431725Abstract: Various methods and devices are described for retaining a medical implant within a body cavity. According to one aspect, one or more plications are formed and the medical device is coupled to or seated against the plication(s). A patch may be positioned between tissue layers forming the plication so as to reinforce the tissue adhesion forming between the tissue layers.Type: GrantFiled: July 23, 2004Date of Patent: October 7, 2008Assignee: Synecor, LLCInventors: Richard S. Stack, Dan Balbierz, John Lunsford, Kevin van Bladel, William S. Eubanks, Jr., William L. Athas, Richard A. Glenn, Richard Kouri
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Patent number: 7377939Abstract: Endolumenal prostheses that readily and extensively convert from a delivery configuration to a deployed configuration are disclosed. Endolumenal prostheses may be fabricated from one or more shape memory polymers, a high modulus elastomer, a polymer that is both elastomeric and exhibits shape memory behavior, a hydrogel, or some combination thereof. Polymers used to fabricate the prostheses are selectively synthesized to exhibit desired characteristics such as crystallinity, strain fixity rate, strain recovery rate, elasticity, tensile strength, mechanical strength, cross-linking density, extent physical cross-linking, extent of covalent cross-linking, extent of interpenetrating networks, rate of erosion, heat of fusion, crystallization temperature, and acidity during erosion. The endolumenal prostheses convert to the deployed configuration following delivery to a treatment site, upon exposure to an initiator either present within the body naturally or introduced into the body.Type: GrantFiled: November 15, 2004Date of Patent: May 27, 2008Assignee: SyneCor, LLCInventors: Michael S. Williams, Robert S. Langer, Yadong Wang
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Patent number: 7363082Abstract: A flexible, hermetically sealed enclosure device allows for the controlled insertion of an implantable device into the body of a patient. A series of bellows can be used to interconnect a number of rigid containers, each containing electronic or other components necessary for the implantable device. The bellows provide flexibility, columnar strength, and torqueability (for steering), while protecting the internal components. The bellows also can be welded to the containers to form a hermetic seal that can be electrically continous, whereby standard wiring and components can be used without fear of corrosion or contamination. Such an enclosure can be used with systems such as an intravascular implantable pacing, drug delivery, or defibrillation system.Type: GrantFiled: March 24, 2005Date of Patent: April 22, 2008Assignee: Synecor LLCInventors: Terrance Ransbury, William L. Athas, Arthur Gwerder
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Patent number: 7354454Abstract: A device for inducing weight loss in a patient includes a tubular prosthesis self-expandable from a collapsed position in which the prosthesis has a first diameter to an expanded position in which the prosthesis has a second, larger, diameter. In a method for inducing weight loss, the prosthesis is placed in the collapsed position and inserted into a stomach of a patient. The prosthesis is allowed to self-expand from the collapsed position to the expanded position and into contact with the walls of the stomach, where it induces feelings of satiety and/or inhibits modulation of satiety-controlling factors such as Ghrelin.Type: GrantFiled: July 16, 2004Date of Patent: April 8, 2008Assignee: Synecor, LLCInventors: Richard S. Stack, Richard A. Glenn, Trevor J. Moody, Fred E. Silverstein, Nathan Every, William S. Eubanks, Jr.
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Patent number: 7285287Abstract: Methods of producing biocompatible intraluminal prostheses are provided and include immersing polymeric material of an intraluminal prosthesis in a densified carbon dioxide composition under controlled conditions such that toxic materials are absorbed by the densified carbon dioxide composition.Type: GrantFiled: September 15, 2003Date of Patent: October 23, 2007Assignee: SyneCor, LLCInventors: Michael S. Williams, Joseph M. DeSimone
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Patent number: 7163554Abstract: A woven tubular endoprosthesis comprising means for locking the endoprosthesis in a deployed configuration is disclosed. The means for locking the endoprosthesis may comprise locking protrusions, notches, a chemical bond, a curable bond, or other mechanism. The woven fibers comprising the endoprosthesis may be hollow and comprise circumferentially oriented polymeric chains, and may be filled with a curable material. A method of treatment using an endoprosthesis according to the invention is also disclosed.Type: GrantFiled: November 8, 2004Date of Patent: January 16, 2007Assignee: SyneCor, LLCInventors: Michael S. Williams, Richard A. Glenn, Jeffrey A. Smith, Kevin D. Holbrook, Joseph M. DeSimone
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Patent number: 7146984Abstract: A prosthetic device is described that is positionable within the gastro-esophageal junction region of a patient. The prosthetic device includes a proximal opening and a distal orifice that is adjustable in size prior to and/or following implantation. During use, the prosthetic device is attached to tissue of the gastro-esophageal junction region of the patient, with the device positioned such that food ingested by the patient passes from the esophagus through the proximal opening into the interior of the prosthetic device, and eventually exits the prosthetic device via the distal opening.Type: GrantFiled: March 12, 2003Date of Patent: December 12, 2006Assignee: Synecor, LLCInventors: Richard S. Stack, Fred E. Silverstein, Nathan Every, William L. Athas, Michael S. Williams, Richard A. Glenn, John Lunsford, Dan Balbierz
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Patent number: 7141061Abstract: Novel endoprostheses comprising one or more photocurable materials are disclosed. Said endoprostheses may comprise regions wherein said photocurable materials are selectively disposed about said endoprosthesis and are cured according to desired parameters to achieve varying desired properties. Said properties may include but are not limited to cross-linking density, material density, modulus of elasticity, rate of erosion, extensibility, compressibility, mechanical strength, tensile strength, crystallinity, diffusion coefficient, and permeability.Type: GrantFiled: January 15, 2003Date of Patent: November 28, 2006Assignee: SyneCor, LLCInventors: Michael S. Williams, Kevin D. Holbrook, Richard A. Glenn, Jeffrey A. Smith, Joseph M. DeSimone
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Patent number: 7121283Abstract: A device for inducing weight loss in a patient includes a tubular prosthesis self-expandable from a collapsed position in which the prosthesis has a first diameter to an expanded position in which the prosthesis has a second, larger, diameter. In a method for inducing weight loss, the prosthesis is placed in the collapsed position and inserted into a stomach of a patient. The prosthesis is allowed to self-expand from the collapsed position to the expanded position and into contact with the walls of the stomach, where it induces feelings of satiety and/or inhibits modulation of satiety-controlling factors such as Ghrelin.Type: GrantFiled: March 4, 2004Date of Patent: October 17, 2006Assignee: Synecor, LLCInventors: Richard S. Stack, Richard A. Glenn, Trevor J. Moody, Fred E. Silverstein, Nathan Every, William S. Eubanks, Jr.
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Patent number: 7111627Abstract: A device for inducing weight loss in a patient includes a tubular prosthesis self-expandable from a collapsed position in which the prosthesis has a first diameter to an expanded position in which the prosthesis has a second, larger, diameter. In a method for inducing weight loss, the prosthesis is placed in the collapsed position and inserted into a stomach of a patient. The prosthesis is allowed to self-expand from the collapsed position to the expanded position and into contact with the walls of the stomach, where it induces feelings of satiety and/or inhibits modulation of satiety-controlling factors such as Ghrelin.Type: GrantFiled: June 9, 2003Date of Patent: September 26, 2006Assignee: Synecor, LLCInventors: Richard S. Stack, Richard A. Glenn, Trevor J. Moody, Fred E. Silverstein, Nathan Every, William S. Eubanks, Jr.
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Patent number: 7097665Abstract: Described herein is a positioning tool having an elongate portion for carrying a medical implant. Also described is a method of positioning a medical implant using an elongate positioning tool. One form of the method includes positioning a medical implant on a distal portion of an elongate positioning tool, inserting the positioning tool with the implant thereon into a body cavity, manipulating the positioning tool to position the implant into contact with tissue at an attachment location, attaching the implant to surrounding tissue at the attachment location, separating the implant from the positioning tool, and withdrawing the positioning tool from the body. In a preferred embodiment, the position of the implant is visually confirmed using an endoscope before the implant is attached to surrounding tissue. In one embodiment, the implant is a satiation device and the body cavity is the esophagus and/or stomach.Type: GrantFiled: January 16, 2003Date of Patent: August 29, 2006Assignee: Synecor, LLCInventors: Richard S. Stack, Richard A. Glenn, Dan Balbierz, John Lunsford, William L. Athas
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Patent number: 7082336Abstract: The present application describes an intravascular implantable pacing and/or defibrillation system. The described system includes a pulse generator that is implantable within a blood vessel and proportioned to blood flow through the blood vessel, and at least one lead attachable to the pulse generator. During implantation, the pulse generator is introduced into a patient's vasculature, advanced to a desired vessel and anchored in place within the vessel. The lead or leads are placed within the heart or surrounding vessels as needed to deliver electrical pulses to the appropriate location.Type: GrantFiled: June 4, 2003Date of Patent: July 25, 2006Assignee: Synecor, LLCInventors: Terrance Ransbury, Michael S. Williams
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Patent number: 6932930Abstract: Methods of manufacturing polymeric intraluminal prostheses include annealing the polymeric material to selectively modify the crystallinity thereof. Annealing may be utilized to selectively modify various properties of the polymeric material of an intraluminal prosthesis, including: selectively increasing the modulus of the polymeric material; selectively increasing the hoop strength of the intraluminal prosthesis; selectively modifying the elution rate (increase or decrease) of a pharmacological agent subsequently disposed on or within the annealed polymeric material; selectively increasing/decreasing stress in the intraluminal prosthesis; and selectively modifying the polymeric material such that it erodes at a different rate.Type: GrantFiled: November 4, 2003Date of Patent: August 23, 2005Assignee: Synecor, LLCInventors: Joseph M. DeSimone, Michael S. Williams