Abstract: The invention provides polypeptides, polysaccharide-polypeptide conjugates, and expression vectors for treating or preventing pneumococcal infection. The compositions induce an anti-pneumococcal immune response when administered to a mammal. The compositions can be used prophylactically to vaccinate an individual and/or therapeutically to induce a therapeutic immune response in an infected individual.
Type:
Grant
Filed:
May 14, 2007
Date of Patent:
September 8, 2009
Assignee:
Synergy America, Inc.
Inventors:
Michael C. Chen, Chuang-Jiun Chiou, Zhongming Li, Dong-Sheng Chen
Abstract: The invention provides polypeptides, polysaccharide-polypeptide conjugates, and expression vectors for treating or preventing pneumococcal infection. The compositions induce an anti-pneumococcal immune response when administered to a mammal. The compositions can be used prophylactically to vaccinate an individual and/or therapeutically to induce a therapeutic immune response in an infected individual.
Type:
Application
Filed:
May 14, 2007
Publication date:
August 21, 2008
Applicant:
Synergy America, Inc.
Inventors:
Michael C. Chen, Chuang-Jiun Chiou, Zhongming Li, Dong-Sheng Chen
Abstract: The invention provides polypeptides, polysaccharide-polypeptide conjugates, and expression vectors for treating or preventing pneumococcal infection. The compositions induce an anti-pneumococcal immune response when administered to a mammal. The compositions can be used prophylactically to vaccinate an individual and/or therapeutically to induce a therapeutic immune response in an infected individual.
Type:
Grant
Filed:
November 6, 2003
Date of Patent:
May 15, 2007
Assignee:
Synergy America, Inc.
Inventors:
Michael C. Chen, Chuang-Jiun Chiou, Zhongming Li, Dong-Sheng Chen