Abstract: The present invention refers to biochemistry, namely to new peptide compounds having the ability to selectively block the muscle-type nicotinic acetylcholine receptor. The claimed compounds have common formula (I): X1-X2-X3-Pro-X4-Pro-X5 (SEQ ID NO: 54), where X1 is chosen within H, Ac—, Palm-; X2 is chosen within Trp, Tyr; X3 is chosen within Trp, Tyr; X4 is chosen within Lys, Orn, Dbu, Dpr, Arg; X5 is chosen within —OH, —NH2, —OCH3, —OC2H5, —NH—C6H5. The invention can be applied in cosmetics for smoothing mimic and age-related Wrinkles.
Type:
Grant
Filed:
January 20, 2014
Date of Patent:
January 24, 2017
Assignee:
Syneuro LLC
Inventors:
Maxim Nurgayanovich Zhmak, Yury Nikolaevich Utkin, Tatyana Viktorovna Andreeva, Denis Sergeevich Kudryavtsev, Elena Viktorovna Kryukova, Viktor Ionovich Tsetlin, Igor Evgen'evich Kasheverov, Vladislav Gennad'evich Starkov, Irina Valer'evna Shelukhina