Abstract: Apparatus (10) for the production of radioisotopes that has a connection element (9) that may be connected to a radiation source, a foil holder block (8) connected to this connection element (9) and a first foil (80a) secured by the foil holder block (8) in a beam channel (11) delimited by the connection element (9), the foil holder block (8) and a cooling connection block (7) connected to this, a target holder (4) connected to the cooling connection block (7) and a target holder actuator (2) driving this, a dissolution chamber (5) that may be connected to the target holder (4), characterised by that the target holder (4) has two or more cavities (41), which cavities (41) are adapted for accommodating a target (42) and a dissolution chamber actuator (3) is connected to the dissolution chamber (5), and a method for producing radioisotopes in such an apparatus.