Abstract: Genetically engineered bacteria, pharmaceutical compositions thereof, and methods of modulating and treating diseases associated with hyperphenylalaninemia are disclosed.
Type:
Grant
Filed:
May 13, 2016
Date of Patent:
April 7, 2020
Assignee:
Synlogic Operating Company Inc.
Inventors:
Dean Falb, Vincent M. Isabella, Jonathan W. Kotula, Paul F. Miller, Yves Millet, Sarah Rowe
Abstract: Genetically programmed microorganisms, such as bacteria or virus, pharmaceutical compositions thereof, and methods of modulating and treating cancers are disclosed.
Type:
Application
Filed:
January 5, 2018
Publication date:
November 7, 2019
Applicants:
Synlogic Operating Company, Inc., Synlogic Operating Company, Inc.
Inventors:
Dean Falb, Jonathan W. Kotula, Vincent M. Isabella, Paul F. Miller, Suman Machinani, Saurabh Saha, Adam B. Fisher, Yves Millet, Ning Li, Jose M. Lora
Abstract: Genetically engineered bacteria, pharmaceutical compositions thereof, and methods of treating or preventing autoimmune disorders, inhibiting inflammatory mechanisms in the gut, and/or tightening gut mucosal barrier function are disclosed.
Type:
Grant
Filed:
March 2, 2016
Date of Patent:
April 30, 2019
Assignee:
Synlogic Operating Company, Inc.
Inventors:
Dean Falb, Vincent M. Isabella, Jonathan W. Kotula, Paul F. Miller
Abstract: Genetically engineered bacteria, pharmaceutical compositions thereof, and methods of modulating and treating diseases associated with hyperphenylalaninemia are disclosed.
Type:
Grant
Filed:
May 13, 2016
Date of Patent:
February 5, 2019
Assignee:
Synlogic Operating Company, Inc.
Inventors:
Dean Falb, Vincent M. Isabella, Jonathan W. Kotula, Paul F. Miller, Sarah Rowe, Yves Millet