Abstract: A novel method and compositions for the local treatment of Meniere's disease, tinnitus and hearing loss are described. The treatment is based on the administration of a therapeutically effective amount of a prostaglandin of the F-type to the inner ear. The treatment can be either continuous or intermittent and may involve the use of pumps, gels, or slow release drug inserts.
Type:
Grant
Filed:
January 15, 2002
Date of Patent:
March 3, 2009
Assignee:
Synphora AB
Inventors:
Helge Rask-Andersen, Johan Stjernschantz
Abstract: A selective EP2 or EP4 prostanoid receptor agonist can be used to treat female sexual dysfunction. Salts and esters of the agonists can also be used. Formulations comprising such agonists, salts, or esters can be in the form of a cream, gel, ointment, or solid, useful for topical administration.
Abstract: This invention is related to a method whereby scar formation in the drainage fistula and subconjunctival bleb created during and after glaucoma surgery using a prostaglandin subtype A or J.
Abstract: Compositions and methods for treatment of impotence or erectile dysfunction employ prostaglandins that are selective EP2 or EP4 prostanoid receptor agonists. The compositions can be formulated for intracavernous injection, or for transurethral or transdermal application.