Abstract: The invention concerns the use of a linear peptide paired with an active substance for diagnosing or treating a CNS pathology by preparing a medicine capable of crossing the blood brain barrier to be used for diagnosis or treatment of a pathology localized in the CNS.
Type:
Grant
Filed:
November 26, 1999
Date of Patent:
July 15, 2008
Assignee:
SYNT:EM
Inventors:
Philippe Clair, Michel Kaczorek, Jamal Temsamani
Abstract: A peptide molecule that interferes with an HLH domain of TAL-1 including at least 10 successive amino acids from the HLH domain of TAL-1 of sequence: QQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLA (SEQ ID No. 1) or an equivalent sequence; and a pharmaceutical composition comprising at least one peptide molecule as an active ingredient, and an acceptable vehicle.
Type:
Application
Filed:
February 2, 2005
Publication date:
July 12, 2007
Applicant:
SYNT:EM
Inventors:
Daniele Mathieu, Jamal Temsamani, Michel Kaczorek