Abstract: Novel peptides are disclosed which correspond to epitopes of the HIV-1 gp120 protein. These antigenic peptides induce antibody-dependent cellular cytotoxicity against HIV, and thus are useful in immunization against HIV infection and induction of a heightened immune response to HIV.
Type:
Grant
Filed:
June 20, 1995
Date of Patent:
November 24, 1998
Assignee:
Syntello Vaccine Development KB
Inventors:
Anders Vahlne, Bo Syennerholm, Lars Rymo, Stig Jeansson, Peter Horal
Abstract: In accordance with the present invention, novel peptides corresponding to epitopes of human immunodeficiency virus-1 gp120 protein and analogues and homologs thereof are provided. These peptides can be utilized alone or in combination, uncoupled or coupled to other molecules or substrates. The peptides are useful in immunization against human immunodeficiency virus infection and in production of polyclonal and monoclonal antibodies.
Type:
Grant
Filed:
March 27, 1995
Date of Patent:
December 31, 1996
Assignee:
Syntello Vaccine Development KB
Inventors:
Anders Vahlne, Bo Svennerholm, Lars Rymo, Stig Jeansson, Peter Horal