Patents Assigned to Synthemed, Inc.
  • Polymeric compositions
    Patent number: 7879356
    Abstract: The present invention relates to novel bioabsorbable polymeric compositions based upon AB polyester polyether or related diblocks and triblocks. Compositions according to the present invention may be used in medical applications, for example, for reducing or preventing adhesion formation subsequent to medical procedures such as surgery, for producing surgical articles including stents and grafts, as coatings, sealants, lubricants, as transient barriers in the body, for materials which control the release of bioactive agents in the body, for wound and burn dressings and producing biodegradable articles, among numerous others.
    Type: Grant
    Filed: March 13, 2001
    Date of Patent: February 1, 2011
    Assignee: Synthemed, Inc.
    Inventors: Daniel Cohn, Theodor Stern, Avraham Levi
  • Reverse thermal gellation polymer of chain-extended optional polyester-terminated PEO-PPO-PEO
    Patent number: 7569643
    Abstract: The present invention relates to novel polymeric compositions based upon An(BCB)An polyester/polyether multi-blocks. Compositions according to the present invention exhibit unexpectedly exceptional reverse thermal gellation properties and in certain cases, relatively low viscosities at approximately room temperature and extremely high viscosities at temperatures above room temperature (preferably at approximately physiological or body temperature, i.e., within a temperature range of about 32-40° C.). Compositions according to the present invention may be used advantageously in applications which make use of their reverse thermal gellation properties. Preferred applications for use of the present compositions include, for example, medical applications which make advantageous use of the inherent composition characteristic of being of relatively low viscosity at room temperature and much higher viscosity at elevated temperatures, especially body temperature.
    Type: Grant
    Filed: December 2, 2004
    Date of Patent: August 4, 2009
    Assignee: Synthemed, Inc.
    Inventors: Daniel Cohn, Avraham Levi
  • Methods and compositions for reducing or eliminating post-surgical adhesion formation
    Patent number: 7202281
    Abstract: The present invention relates to a method for reducing adhesions associated with post-operative surgery. The present method comprises administering or affixing a polymeric composition preferably comprising chain extended, coupled or crosslinked polyester/poly(oxyalkylene) ABA triblocks or AB diblocks having favorable EO/LA ratios to a site in the body which has been subjected to trauma, e.g. by surgery, excision or inflammatory disease. In the present invention, the polymeric material provides a barrier to prevent or reduce the extent of adhesions forming.
    Type: Grant
    Filed: December 31, 2003
    Date of Patent: April 10, 2007
    Assignee: Synthemed, Inc.
    Inventors: Daniel Cohn, Eli Pines, Anna Hotovely