Abstract: In order to improve the detection sensitivity of MUSTag, the present invention provides an antibody complex including a nucleic acid chain as a label, an antibody to specifically recognize the antigen and an adaptor moiety linking the nucleic acid chain and the antibody, wherein the adaptor moiety includes an immunoglobulin binding domain of Protein G, Protein A or Protein L for binding with the antibody, and the adaptor moiety and the antibody are chemically cross-linked to form a cross-linked antibody complex.
Type:
Application
Filed:
June 30, 2009
Publication date:
August 4, 2011
Applicants:
TOKYO METROPOLITAN ORGANIZATION FOR MEDICAL RESEARCH, SYNTHERA TECHNOLOGIES CO., LTD.
Abstract: The present invention provides a method for identifying and detecting multiple types of target substances contained in a specimen, comprising the steps of: contacting the target substances immobilized and/or nonimmobilized on a support with labeled binders capable of identifying corresponding types of target substances so as to form complexes between the target substances and the binders; and detecting the labels in the binders forming the complexes.
Type:
Application
Filed:
November 1, 2005
Publication date:
December 25, 2008
Applicants:
TOKYO METROPOLITAN ORGANIZATION FOR MEDICAL RESEAR, SYNTHERA TECHNOLOGIES CO., LTD.