Abstract: A method for reconstruction of a resectioned portion of a bone includes connecting a first link to a second link through a flexible connection to form an elongated linkage that extends along a substantially longitudinal direction, providing a flexible connector configured to work in tandem with the flexible connection to adjust the first and second links relative to each other to adapt to a shape of the bone in at least one of a directional orientation about an axis that extends in the vertical direction and an angular orientation about an axis that extends in the longitudinal direction, and providing a locking member configured for insertion through the aperture, wherein the locking member is configured to apply a biasing force to the connector and inhibit adjustment of the at least one of the directional orientation and the angular orientation of the first link relative to the second link.

Abstract: An orthopedic prosthesis for use in a hip replacement surgery. The orthopedic prosthesis includes a metallic foam shell and a metallic core. The metallic core includes a neck configured to receive a femoral head component and a stem extending through the metallic foam shell.

Abstract: An alloy and an implant having a three-dimensional structure based on such alloy. The alloy comprises a monophasic MgZn alloy containing from 2.0 wt. % Zn to 6 wt. % Zn, having less than 0.001 wt. % of one or more other elements with the remainder being Mg. In some embodiments, the alloy is substantially free of microgalvanic elements. In some embodiments, the alloy includes a MgZnCa alloy containing nanosized precipitates being less noble than the Mg matrix alloy and having a Zn content ranging from 3.0 wt. % Zn to 6 wt. % Zn and a calcium content ranging from 0.0005 wt. % to 1.0 wt. %, having less than 0.001 wt. % of one or more other elements with the remainder being Mg. In other embodiments, the alloy includes a MgZnCa alloy containing nanosized precipitates being less noble than the Mg matrix alloy, a plurality of nanosized precipitates being more noble than the Mg matrix and having a Zn content ranging from 3.0 wt. % Zn to 6 wt. % Zn, a calcium content ranging from 0.0005 wt. % to 1.0 wt.

Abstract: This invention encompasses methods, pharmaceutical compositions, and kits for modulating (e.g. reducing) the production of pro-inflammatory mediators involved in the pathology of a lung disease, disorder, and/or injury in a patient having the lung disease, disorder, and/or injury. The invention also encompasses methods, pharmaceutical compositions, and kits for inhibiting the production of pro-inflammatory mediators involved in the pathology of a lung disease, disorder, and/or injury in a patient having the lung disease, disorder, and/or injury. In one embodiment, the umbilical cord tissue-derived cells are isolated from human umbilical cord tissue substantially free of blood, are capable of self-renewal and expansion in culture, lack the production of CD117 or CD45, and do not express hTERT or telomerase.

Abstract: The disclosure relates and extends to a light source having a strobing or pulsing sequence suitable for use with a CMOS sensor that does not require, have, or use a global shutter. Instead, the CMOS sensor synchronizes the strobing input with the blanking portion of the sensor readout pattern and disables the strobing during sensor readout, or when the strobing would otherwise leave artifacts in the image. The CMOS sensor freezes its readout during the strobing.

Abstract: Insertion and expansion devices for use in inserting motion discs, and associated methods of use.

Abstract: A method of revising a patient having a fusion cage implanted within a spinal column, involving percutaneously delivering a first end of a tube to the spinal column, fluidly connecting the first end of the tube to the fusion cage, and delivering a bone growth agent into the fusion cage through the tube.

Abstract: A spinal distractor for distracting opposed vertebrae in which a pair of elements are threadably connected by a screw having opposing threads, wherein actuating the screw spreads the elements apart and pushes the vertebrae apart.

Abstract: The disclosure extends to methods, systems, and computer program products for producing an image in light deficient environments and associated structures, methods and features. The features of the systems and methods described herein may include providing improved resolution and color reproduction.

Abstract: An alloy and an implant having a three-dimensional structure based on such alloy. The alloy comprises a MgZnCa alloy containing nanosized precipitates being less noble than the Mg matrix alloy and having a Zn content ranging 0.1 wt. % Zn to 2 wt. % Zn and a calcium content ranging from 0.2 wt. % to 0.5 wt. %, and having less than 0.04 wt. % of one or more other elements with the remainder being Mg. For these micro-alloys, any second phase generated during the solidification process can be completely dissolved by a solution heat treatment. Finely dispersed nanosized precipitates can then be generated by a subsequent aging heat treatment step. These precipitates are used to “pin” the grain boundaries and to prevent the coarsening of the grain structure during further processing to achieve grain sizes below 5 ?m.

Abstract: An intervertebral implant includes an insertion end, an opposing engagement end, and first and second opposed main surfaces configured to contact respective adjacent vertebral endplates. Each of the first and second main surfaces has an anterior edge, a posterior edge, and extends between the insertion and engagement ends. Anterior and posterior walls are formed between the first and second main surfaces and along the respective anterior and posterior edges and converge at the insertion and engagement ends. A slot is formed at the engagement end and extends continuously between and at least partially along the anterior and posterior walls. A post is positioned within the slot, spaced from at least one of the anterior and posterior walls and extending at least partially between the first and second main surfaces. The post includes a plurality of exposed facets and is configured for engagement with a pivotable insertion instrument.

Abstract: An electrical insulator is applied to a bone anchor, for instance of a bone implant, such as an external fixation frame, so as to prevent undesirable temperature increases in the bone anchor and surrounding anatomical tissue when subjected magnetic resonance imaging.

Abstract: A surgical apparatus having a locking mechanism that receives a cutting burr and that may include a loading and running position. The locking mechanism may include a motor driven spindle that carries a locking pawl and a detent pawl that lock the cutting burr in place an prevent the cutting burr from inadvertently falling out of the surgical drill instrument when in its load position. A diamond-shaped portion of the cutting burr may be formed in a six-sided diamond configuration and a perpendicular back end surface. The end of the cutting burr may include another diamond-shaped portion formed in a six-sided diamond shape surface that mates with a complementary surface formed in the receiving end of the spindle of the motor/locking mechanism. In an aspect, the attachment of the cutting burr is such that the cutting burr has substantially zero axial movement and runs true in the running condition.

Abstract: A torque limiting instrument is disclosed configured to drive a shaft to rotate in a select direction in response to an applied torque until the applied torque reaches a predetermined threshold. Thus, when the torque limiting instrument drives a bone screw into bone, the bone screw is advanced into the bone until the torque applied to the torque limiting instrument reaches the predetermined threshold, at which point the torque limiting instrument will no longer communicate the applied torque to the bone screw.

Abstract: Cells derived from postpartum placenta and methods for their isolation are provided by the invention. The invention further provides cultures and compositions of the placenta-derived cells. The placenta-derived cells of the invention have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications.

Abstract: An anatomical implant application, such as a bone implant application for instance, can receive an anatomical image that is representative of an anatomical structure. The anatomical implant application can generate an implant image that is associated with the anatomical structure. The generated implant image can define an inner surface that faces the anatomical image. A plurality of distances can be determined from respective locations of the inner surface of the implant image to the anatomical image in respective straight lines. The distances may represent a superimposition of the implant image over the anatomical image. The distances may be compared to a tolerance. The inner surface may be repositioned so as to change at least the select one of the distances. An implant, such as a bone implant for instance, may be fabricated in accordance with data that is associated with the implant image.

Abstract: A modular bone fixation linkage includes a plurality of interconnected links that can angulate with respect to an adjacent one of the links about at least one axis, such as three axes. The links can further include fixation holes that are configured to receive bone anchors that secure the links to an underlying anatomical structure.

Abstract: The disclosure extends to devices, systems and methods for connecting one or more sensors to one or more printed circuit boards (PCB) in the distal end or tip of a scope. The disclosure also extends to a connector assembly for an image sensor for protecting the sensor and conveying information from the sensor to the PCB.

Abstract: An intervertebral fusion device having a cage having an opening or window in its front wall that allows for the insertion of bone graft therethrough after the cage has been placed into the disc space. The device further has a faceplate that covers the front wall of the cage and provides features for securing bone screws to the adjacent vertebral bodies.

Abstract: An intracranial, light-emitting implant for providing therapy to a patient having Alzheimer's Disease.