Patents Assigned to Synthetic Genetics
  • Novel amphiphilic nucleic acid conjugates
    Patent number: 4904582
    Abstract: Novel oligonucleotide conjugates are provided, where oligonucleotides are joined through a linking arm to a hydrophobic moiety. The resulting conjugates are more efficient in membrane transport, so as to be capable of crossing the membrane and effectively modulating a transcriptional system. In this way, the compositions can be used in vitro and in vivo, for studying cellular processes, protecting mammalian hosts from pathogens, and the like.
    Type: Grant
    Filed: June 11, 1987
    Date of Patent: February 27, 1990
    Assignee: Synthetic Genetics
    Inventor: Richard H. Tullis