Patents Assigned to Syqe Medical Ltd.
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Patent number: 11071712Abstract: There is provided in accordance with an exemplary embodiment of the invention, a device and a method for controlled extraction of at least one active substance from at least one type of plant matter by application of heat, the device comprising: a heating element adapted to apply heat to an area of the plant matter to extract the substance; and a mechanism adapted for moving the plant matter relative to the heating element. Optionally, the active substance is a restricted substance. There is also provided in accordance with an exemplary embodiment of the invention, a method of monitoring and controlling inhalation of a restricted substance. There is provided in accordance with an exemplary embodiment of the invention, a method of manufacturing a tape of plant matter comprising an active substance.Type: GrantFiled: August 30, 2017Date of Patent: July 27, 2021Assignee: Syqe Medical Ltd.Inventors: Perry Davidson, Aaron Schorr, Arie Holtz, Will Pong, Binyamin Schwartz
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Patent number: 11033488Abstract: There is provided in accordance with an exemplary embodiment of the invention, a device and a method for controlled extraction of at least one active substance from at least one type of plant matter by application of heat, the device comprising: a heating element adapted to apply heat to an area of the plant matter to extract the substance; and a mechanism adapted for moving the plant matter relative to the heating element. Optionally, the active substance is a restricted substance. There is also provided in accordance with an exemplary embodiment of the invention, a method of monitoring and controlling inhalation of a restricted substance. There is provided in accordance with an exemplary embodiment of the invention, a method of manufacturing a tape of plant matter comprising an active substance.Type: GrantFiled: August 30, 2017Date of Patent: June 15, 2021Assignee: Syqe Medical Ltd.Inventors: Perry Davidson, Aaron Schorr, Arie Holtz, Will Pong, Binyamin Schwartz
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Publication number: 20210023316Abstract: Some embodiments relate to a method for providing, during a single inhalation from an inhaler, a controllable ratio between at least a first active substance and a second active substance provided from the same source material, comprising: defining a ratio between the first and second active substances to be delivered to a user; setting operation parameters in accordance with the ratio, the operation parameters including at least one of a heating profile of the source material and an airflow profile through the source material; and operating the inhaler according to the operation parameters to deliver to the user, during a single inhalation, at least the first and second active substances at the defined ratio.Type: ApplicationFiled: February 14, 2019Publication date: January 28, 2021Applicant: Syqe Medical Ltd.Inventors: Aaron SCHORR, Tal LUPO, Asaf KROLL, Binyamin SCHWARTZ, Nimrod RESHEF, Daniella ATZMONY
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Publication number: 20200121868Abstract: According to some embodiments there is provided a replaceable flow tract for use with an inhaler device which delivers at least one substance to a user, the inhaler device comprising a housing shaped to receive the flow tract and to further receive a construct comprising source material from which the at least one substance is released; the replaceable flow tract comprising: a conduit comprising: a first opening; a second opening configured for being in fluid communication with a mouthpiece; and a third opening having an elastic sealing member extending therefrom, the elastic sealing member shaped and sized for pressing against the construct when the construct is within the housing.Type: ApplicationFiled: April 18, 2018Publication date: April 23, 2020Applicant: Syqe Medical Ltd.Inventors: Nimrod RESHEF, Itay KURGAN, Avishay DENIZEL, Geva ROSENTHAL KAPLAN, Roee LIFSHITZ, Abraham MEYER, Binyamin SCHWARTZ, Aaron SCHORR
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Publication number: 20190290862Abstract: An inhaler device for pulmonary delivery of at least one substance from a drug dose cartridge to an inhaling user, including: a first conduit for conducting a carrier airflow to a proximal opening of a mouthpiece for use by the user; a holder configured to position the dose cartridge within the carrier airflow; and a second conduit for conducting a shunting airflow to the mouthpiece without passing through the dose cartridge position. In some embodiments, a controller connected to a valve controls a rate of carrier airflow, for example by controlling the shunting airflow, based on a sensor indication of airflow rate and a target airflow profile.Type: ApplicationFiled: June 11, 2019Publication date: September 26, 2019Applicant: Syqe Medical Ltd.Inventors: Perry DAVIDSON, Aaron SCHORR, Binyamin SCHWARTZ
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Patent number: 10369304Abstract: An inhaler device for pulmonary delivery of at least one substance from a drug dose cartridge to an inhaling user, including: a first conduit for conducting a carrier airflow to a proximal opening of a mouthpiece for use by the user; a holder configured to position the dose cartridge within the carrier airflow; and a second conduit for conducting a shunting airflow to the mouthpiece without passing through the dose cartridge position. In some embodiments, a controller connected to a valve controls a rate of carrier airflow, for example by controlling the shunting airflow, based on a sensor indication of airflow rate and a target airflow profile.Type: GrantFiled: November 29, 2016Date of Patent: August 6, 2019Assignee: Syqe Medical Ltd.Inventors: Perry Davidson, Aaron Schorr, Binyamin Schwartz
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Publication number: 20190009039Abstract: Devices and methods are described for preparing, managing, and/or administering metered doses of substances for vaporized administration. In some embodiments, dose cartridges comprising at least one botanical substance include a heating element integrated into the cartridge in close contact with the botanical substance. In some embodiments, cartridge-mounted doses are stored in a magazine, optionally in carousel form, before use. Transport of a cartridge from a magazine to an electrically operated vaporizing chamber which activates the heating element is provided by a mechanical pickup means.Type: ApplicationFiled: September 14, 2018Publication date: January 10, 2019Applicant: Syqe Medical Ltd.Inventors: Perry DAVIDSON, Aaron SCHORR, Binyamin SCHWARTZ, Roee LIFSHITZ
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Patent number: 10166349Abstract: Some embodiments of the invention relate to an inhaler device for pulmonary delivery of at least one substance from a drug dose cartridge to an inhaling user, comprising: a first conduit for conducting a carrier airflow to a proximal opening of a mouthpiece for use by the user; a holder configured to position the dose cartridge within the carrier airflow; and a second conduit for conducting a shunting airflow to the mouthpiece without passing through the dose cartridge position. In some embodiments, a controller connected to a valve controls a rate of carrier airflow, for example by controlling the shunting airflow, based on a sensor indication of airflow rate and a target airflow profile.Type: GrantFiled: December 28, 2016Date of Patent: January 1, 2019Assignee: Syqe Medical Ltd.Inventors: Perry Davidson, Aaron Schorr, Binyamin Schwartz
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Publication number: 20180344954Abstract: A dose unit including at least one isolated bioactive agent applied on a carrier material in thermal contact with an electrically heating element configured to vaporize a pre-determined amount of the agent for pulmonary delivery thereof is provided herein, as well as devices for effecting vaporization and pulmonary delivery of the isolated agent, and methods for preparing the dose unit, controllably releasing the agent therefrom, methods for pulmonary delivery thereof and methods of treatment of medical conditions treatable by pulmonary delivery of the isolated bioactive agent.Type: ApplicationFiled: August 6, 2018Publication date: December 6, 2018Applicant: Syqe Medical Ltd.Inventors: Perry DAVIDSON, Aaron SCHORR, Asaf KROLL, Binyamin SCHWARTZ
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Publication number: 20180318529Abstract: Provided herein is a method of pulmonary delivering to a subject at least one pharmacologically active agent being in a plant material, which is effected by pulmonary delivering the agent to the subject using a metered dose inhaler device that is configured to vaporize at least one pre-determined vaporized amount of the agent upon controllably heating the plant material, wherein the pre-determined vaporized amount is selected so as to achieve at least one pre-determined pharmacokinetic effect and/or at least one pre-determined pharmacodynamic effect induced by the agent in the subject.Type: ApplicationFiled: July 10, 2018Publication date: November 8, 2018Applicant: Syqe Medical Ltd.Inventors: Perry DAVIDSON, Shlomo ALMOG, Seth KINDLER
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Patent number: 10118006Abstract: Provided herein is a method of pulmonary delivering to a subject at least one pharmacologically active agent being in a plant material, which is effected by pulmonary delivering the agent to the subject using a metered dose inhaler device that is configured to vaporize at least one pre-determined vaporized amount of the agent upon controllably heating the plant material, wherein the pre-determined vaporized amount is selected so as to achieve at least one pre-determined pharmacokinetic effect and/or at least one pre-determined pharmacodynamic effect induced by the agent in the subject.Type: GrantFiled: December 11, 2016Date of Patent: November 6, 2018Assignee: Syqe Medical Ltd.Inventors: Perry Davidson, Shlomo Almog, Seth Kindler
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Patent number: 10099020Abstract: Devices and methods are described for preparing, managing, and/or administering metered doses of substances for vaporized administration. In some embodiments, dose cartridges comprising at least one botanical substance include a heating element integrated into the cartridge in close contact with the botanical substance. In some embodiments, cartridge-mounted doses are stored in a magazine, optionally in carousel form, before use. Transport of a cartridge from a magazine to an electrically operated vaporizing chamber which activates the heating element is provided by a mechanical pickup means.Type: GrantFiled: June 30, 2015Date of Patent: October 16, 2018Assignee: Syqe Medical Ltd.Inventors: Perry Davidson, Aaron Schorr, Binyamin Schwartz, Roee Lifshitz
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Patent number: 10080851Abstract: A dose unit including at least one isolated bioactive agent applied on a carrier material in thermal contact with an electrically heating element configured to vaporize a pre-determined amount of the agent for pulmonary delivery thereof is provided herein, as well as devices for effecting vaporization and pulmonary delivery of the isolated agent, and methods for preparing the dose unit, controllably releasing the agent therefrom, methods for pulmonary delivery thereof and methods of treatment of medical conditions treatable by pulmonary delivery of the isolated bioactive agent.Type: GrantFiled: December 19, 2016Date of Patent: September 25, 2018Assignee: Syqe Medical Ltd.Inventors: Perry Davidson, Aaron Schorr, Asaf Kroll, Binyamin Schwartz
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Patent number: 9993602Abstract: An inhaler device for pulmonary delivery of at least one substance from a drug dose cartridge to an inhaling user, including: a first conduit for conducting a carrier airflow to a proximal opening of a mouthpiece for use by the user; a holder configured to position the dose cartridge within the carrier airflow; and a second conduit for conducting a shunting airflow to the mouthpiece without passing through the dose cartridge position. A controller connected to a valve controls a rate of carrier airflow, for example by controlling the shunting airflow, based on a sensor indication of airflow rate and a target airflow profile.Type: GrantFiled: June 30, 2015Date of Patent: June 12, 2018Assignee: Syqe Medical Ltd.Inventors: Perry Davidson, Aaron Schorr, Binyamin Schwartz
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Publication number: 20170360089Abstract: There is provided in accordance with an exemplary embodiment of the invention, a device and a method for controlled extraction of at least one active substance from at least one type of plant matter by application of heat, the device comprising: a heating element adapted to apply heat to an area of the plant matter to extract the substance; and a mechanism adapted for moving the plant matter relative to the heating element. Optionally, the active substance is a restricted substance. There is also provided in accordance with an exemplary embodiment of the invention, a method of monitoring and controlling inhalation of a restricted substance. There is provided in accordance with an exemplary embodiment of the invention, a method of manufacturing a tape of plant matter comprising an active substance.Type: ApplicationFiled: August 30, 2017Publication date: December 21, 2017Applicant: Syqe Medical Ltd.Inventors: Perry DAVIDSON, Aaron SCHORR, Arie HOLTZ, Will PONG, Binyamin SCHWARTZ
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Patent number: 9839241Abstract: Provided herein is a system that includes a metered dose inhaler device for pulmonary delivering to a subject at least one pre-determined vaporized amount of at least one pharmacologically active agent being in a plant material, wherein vaporization is effected by controllably heating the plant material so as to vaporize a pre-determined vaporized amount of the agent; the system further includes a controller in communication with the inhaler device, configured to control the pre-determined vaporized amount based on data indicative of at least one pharmacodynamic effect induced by the agent in the subject.Type: GrantFiled: December 21, 2016Date of Patent: December 12, 2017Assignee: Syqe Medical Ltd.Inventors: Perry Davidson, Shlomo Almog, Seth Kindler
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Patent number: 9802011Abstract: Devices and methods are described for preparing, managing, and/or administering metered doses of substances for vaporized administration. In some embodiments, dose cartridges including at least one botanical substance include a heating element integrated into the cartridge in close contact with the botanical substance. In some embodiments, cartridge-mounted doses are stored in a magazine, optionally in carousel form, before use. Transport of a cartridge from a magazine to an electrically operated vaporizing chamber which activates the heating element is provided by a mechanical pickup means.Type: GrantFiled: November 29, 2016Date of Patent: October 31, 2017Assignee: Syqe Medical Ltd.Inventors: Perry Davidson, Aaron Schorr, Binyamin Schwartz, Roee Lifshitz
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Patent number: 9775379Abstract: There is provided in accordance with an exemplary embodiment of the invention, a device and a method for controlled extraction of at least one active substance from at least one type of plant matter by application of heat, the device comprising: a heating element adapted to apply heat to an area of the plant matter to extract the substance; and a mechanism adapted for moving the plant matter relative to the heating element. Optionally, the active substance is a restricted substance. There is also provided in accordance with an exemplary embodiment of the invention, a method of monitoring and controlling inhalation of a restricted substance. There is provided in accordance with an exemplary embodiment of the invention, a method of manufacturing a tape of plant matter comprising an active substance.Type: GrantFiled: December 22, 2011Date of Patent: October 3, 2017Assignee: Syqe Medical Ltd.Inventors: Perry Davidson, Aaron Schorr, Arie Holtz, Will Pong, Binyamin Schwartz
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Patent number: D857879Type: GrantFiled: December 6, 2016Date of Patent: August 27, 2019Assignee: Syqe Medical Ltd.Inventors: Itay Kurgan, Shay Landa, Geva Rosenthal
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Patent number: D858745Type: GrantFiled: June 4, 2017Date of Patent: September 3, 2019Assignee: Syqe Medical Ltd.Inventors: Itay Kurgan, Avishay Denizel, Geva Rosenthal