Abstract: Aspects of the invention relate to a novel mesenchymal stem cell line (hb-MSC), a culture medium conditioned by the hb-MSC line, and various hb-MSC compositions. The hb-MSC compositions may include a plurality of hb-MSCs, the hb-MSC conditioned medium, or a combination thereof. The hb-MSC compositions may also include one or more of an antimicrobial agent, a film-forming agent, an appropriate carrier, as well as other additives as determined by the application. Also described are methods of use for the hb-MSC cells, the conditioned medium, and the compositions, including methods of treating or preventing bovine mastitis.
Type:
Grant
Filed:
May 31, 2017
Date of Patent:
July 5, 2022
Assignee:
T-Helper Cell Technologies, LLC
Inventors:
Anatoliy Andreevich Sokolov, Antonina Ivanovna Kolesnikova, Andrei Igorevich Dovgii, Artem Andreevich Sokolov, Nikolay Vladimirovich Adrianov
Abstract: Aspects of the invention relate to a novel mesenchymal stem cell line (hb-MSC), a culture medium conditioned by the hb-MSC line, and various hb-MSC compositions. The hb-MSC compositions may include a plurality of hb-MSCs, the hb-MSC conditioned medium, or a combination thereof. The hb-MSC compositions may also include one or more of an antimicrobial agent, a film-forming agent, an appropriate carrier, as well as other additives as determined by the application. Also described are methods of use for the hb-MSC cells, the conditioned medium, and the compositions, including methods of treating or preventing bovine mastitis.
Type:
Application
Filed:
May 31, 2017
Publication date:
November 19, 2020
Applicant:
T-HELPER CELL TECHNOLOGIES, LLC
Inventors:
Anatoliy Andreevich SOKOLOV, Antonina Ivanovna KOLESNIKOVA, Andrei Igorevich DOVGII, Artem Andreevich SOKOLOV, Nikolay Vladimirovich ADRIANOV
Abstract: Aspects of the invention relate to a novel mesenchymal stem cell line (hb-MSC), a culture medium conditioned by the hb-MSC line, and various hb-MSC compositions. The hb-MSC composition may include a plurality of hb-MSCs, an hb-MSC conditioned medium, or a combination thereof. The hb-MSC composition may also include an appropriate carrier. Also described are methods of use for the hb-MSC cells, the conditioned medium and compositions thereof.
Type:
Grant
Filed:
November 30, 2015
Date of Patent:
August 18, 2020
Assignee:
T-Helper Cell Technologies, LLC
Inventors:
Anatoliy Sokolov, Antonina Ivanovna Kolesnikova, Andrei Igorevich Dovgii
Abstract: Aspects of the invention relate to a novel mesenchymal stem cell line (hb-MSC), a culture medium conditioned by the hb-MSC line, and various hb-MSC compositions. The hb-MSC composition may include a plurality of hb-MSCs, an hb-MSC conditioned medium, or a combination thereof. The hb-MSC composition may also include an appropriate carrier. Also described are methods of use for the hb-MSC cells, the conditioned medium and compositions thereof.
Type:
Application
Filed:
November 30, 2015
Publication date:
November 16, 2017
Applicant:
T-HELPER CELL TECHNOLOGIES, LLC
Inventors:
Anatoliy SOKOLOV, Antonina Ivanovna KOLESNIKOVA, Andrei Igorevich DOVGII