Patents Assigned to Tadashi Matsunaga
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Publication number: 20060269961Abstract: The present invention provides a dendrimer-based biochip, wherein a flow channel through which a solution containing biopolymer molecules is flowed is formed in the substrate of the biochip, a plurality of dendrimer molecules one end of each of which is bound to the walls of the flow channel are formed thereon, and probe biopolymer or antibody molecules are bound to the tips of the dendrimer molecules so that, if the probe biopolymer molecules are bound, then target biopolymer molecules can be captured by means of a complementary combination and, if the antibody molecules are bound, then protein can be extracted by means of antigen-antibody reaction, whereby biopolymers can be retrieved in a highly efficient manner.Type: ApplicationFiled: August 10, 2006Publication date: November 30, 2006Applicants: YOKOGAWA ELECTRIC CORPORATION, Tadashi MATSUNAGAInventors: Kazuhisa Fukushima, Saya Satou, Tadashi Matsunaga, Haruko Takeyama
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Publication number: 20050260600Abstract: The present invention relates to a method of extracting nucleic acid or protein, in which multi-layer dendorimers are formed on the surface of fine particles, amino radicals for capturing nucleic acid or protein are formed on the surface of these dendorimers, and nucleic acid or protein is extracted using these amino radicals. The present invention can greatly and easily increase the recovery ratio of nucleic acid or protein.Type: ApplicationFiled: August 26, 2003Publication date: November 24, 2005Applicants: Tadashi MATSUNAGA, YOKOGAWA ELECTRIC CORPORATIONInventors: Tadashi Matsunaga, Haruko Takeyama, Brandon Yoza, Kazuhisa Fukushima, Saya Satou
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Publication number: 20050130191Abstract: The present invention provides a dendrimer-based biochip, wherein a flow channel through which a solution containing biopolymer molecules is flowed is formed in the substrate of the biochip, a plurality of dendrimer molecules one end of each of which is bound to the walls of the flow channel are formed thereon, and probe biopolymer or antibody molecules are bound to the tips of the dendrimer molecules so that, if the probe biopolymer molecules are bound, then target biopolymer molecules can be captured by means of a complementary combination and, if the antibody molecules are bound, then protein can be extracted by means of antigen-antibody reaction, whereby biopolymers can be retrieved in a highly efficient manner.Type: ApplicationFiled: August 30, 2004Publication date: June 16, 2005Applicants: YOKOGAWA ELECTRIC CORPORATION, TADASHI MATSUNAGAInventors: Kazuhisa Fukushima, Saya Satou, Tadashi Matsunaga, Haruko Takeyama
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Patent number: 5958706Abstract: This invention provides a useful protein-bound magnetic particle which includes a magnetic particle produced in the cell of a magnetic bacterium, and a hybrid protein bound to an organic membrane covering the magnetic particle, and of which the hybrid protein comprises a membrane protein which is originally produced in a state of being bound to the organic membrane, and one or more useful proteins bound biologically through fusion or other binding means to the membrane protein. The protein biologically immobilized does not suffer reduced activity. It is possible to obtain a useful protein such as an enzyme, antibody, etc. immobilized on a magnetic particle, only by cultivating a transformed bacterium, and separating a magnetic particle produced in the cell of the bacterium. When a functional protein is immobilized in this way, it is possible to guide the functional protein magnetically, and to move it to a desired location effectively.Type: GrantFiled: February 9, 1998Date of Patent: September 28, 1999Assignees: TDK Corporation, Tadashi MatsunagaInventors: Tadashi Matsunaga, Shinji Kamiya, Kenryo Namba
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Patent number: 5300128Abstract: A method of plant tissue culture which comprises culturing a tissue or an organ of a plant, a part of the same or cultured cells in a medium containing a culture filtrate and/or an extract of a photosynthetic procaryotic microorganism.Such a culturing method effectively proliferates the plant tissues and cultured cells, and also promotes the formation of adventive embryos, regeneration of the plant body and production of useful substances formed by that plant.Strains of cyanobacteria or photosynthetic bacteria are preferably used as the photosynthetic procaryotic microorganism.Type: GrantFiled: February 25, 1993Date of Patent: April 5, 1994Assignees: Pentel Kabushiki Kaisha, Tadashi MatsunagaInventors: Tadashi Matsunaga, Hitoshi Wake, Mayumi Ono, Kiyoshi Hishinuma, Hironori Umetsu
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Patent number: 5217892Abstract: A method of plant tissue culture which comprises culturing a tissue or an organ of a plant, a part of the same or cultured cells in a medium containing a culture filtrate and/or an extract of a photosynthetic procaryotic microorganism.Such a culturing method effectively proliferates the plant tissues and cultured cells, and also promotes the formation of adventive embryos, regeneration of the plant body and production of useful substances formed by that plant.Strains of cyanobacteria or photosynthetic bacteria are preferably used as the photosynthetic procaryotic microorganism.Type: GrantFiled: July 8, 1992Date of Patent: June 8, 1993Assignees: Pentel Kabushiki Kaisha, Tadashi MatsunagaInventors: Tadashi Matsunaga, Hitoshi Wake, Mayumi Ono, Kiyoshi Hishinuma, Hironori Umetsu