Patents Assigned to Tadashi Matsunaga
  • Publication number: 20060269961
    Abstract: The present invention provides a dendrimer-based biochip, wherein a flow channel through which a solution containing biopolymer molecules is flowed is formed in the substrate of the biochip, a plurality of dendrimer molecules one end of each of which is bound to the walls of the flow channel are formed thereon, and probe biopolymer or antibody molecules are bound to the tips of the dendrimer molecules so that, if the probe biopolymer molecules are bound, then target biopolymer molecules can be captured by means of a complementary combination and, if the antibody molecules are bound, then protein can be extracted by means of antigen-antibody reaction, whereby biopolymers can be retrieved in a highly efficient manner.
    Type: Application
    Filed: August 10, 2006
    Publication date: November 30, 2006
    Applicants: YOKOGAWA ELECTRIC CORPORATION, Tadashi MATSUNAGA
    Inventors: Kazuhisa Fukushima, Saya Satou, Tadashi Matsunaga, Haruko Takeyama
  • Publication number: 20050260600
    Abstract: The present invention relates to a method of extracting nucleic acid or protein, in which multi-layer dendorimers are formed on the surface of fine particles, amino radicals for capturing nucleic acid or protein are formed on the surface of these dendorimers, and nucleic acid or protein is extracted using these amino radicals. The present invention can greatly and easily increase the recovery ratio of nucleic acid or protein.
    Type: Application
    Filed: August 26, 2003
    Publication date: November 24, 2005
    Applicants: Tadashi MATSUNAGA, YOKOGAWA ELECTRIC CORPORATION
    Inventors: Tadashi Matsunaga, Haruko Takeyama, Brandon Yoza, Kazuhisa Fukushima, Saya Satou
  • Publication number: 20050130191
    Abstract: The present invention provides a dendrimer-based biochip, wherein a flow channel through which a solution containing biopolymer molecules is flowed is formed in the substrate of the biochip, a plurality of dendrimer molecules one end of each of which is bound to the walls of the flow channel are formed thereon, and probe biopolymer or antibody molecules are bound to the tips of the dendrimer molecules so that, if the probe biopolymer molecules are bound, then target biopolymer molecules can be captured by means of a complementary combination and, if the antibody molecules are bound, then protein can be extracted by means of antigen-antibody reaction, whereby biopolymers can be retrieved in a highly efficient manner.
    Type: Application
    Filed: August 30, 2004
    Publication date: June 16, 2005
    Applicants: YOKOGAWA ELECTRIC CORPORATION, TADASHI MATSUNAGA
    Inventors: Kazuhisa Fukushima, Saya Satou, Tadashi Matsunaga, Haruko Takeyama
  • Patent number: 5958706
    Abstract: This invention provides a useful protein-bound magnetic particle which includes a magnetic particle produced in the cell of a magnetic bacterium, and a hybrid protein bound to an organic membrane covering the magnetic particle, and of which the hybrid protein comprises a membrane protein which is originally produced in a state of being bound to the organic membrane, and one or more useful proteins bound biologically through fusion or other binding means to the membrane protein. The protein biologically immobilized does not suffer reduced activity. It is possible to obtain a useful protein such as an enzyme, antibody, etc. immobilized on a magnetic particle, only by cultivating a transformed bacterium, and separating a magnetic particle produced in the cell of the bacterium. When a functional protein is immobilized in this way, it is possible to guide the functional protein magnetically, and to move it to a desired location effectively.
    Type: Grant
    Filed: February 9, 1998
    Date of Patent: September 28, 1999
    Assignees: TDK Corporation, Tadashi Matsunaga
    Inventors: Tadashi Matsunaga, Shinji Kamiya, Kenryo Namba
  • Patent number: 5300128
    Abstract: A method of plant tissue culture which comprises culturing a tissue or an organ of a plant, a part of the same or cultured cells in a medium containing a culture filtrate and/or an extract of a photosynthetic procaryotic microorganism.Such a culturing method effectively proliferates the plant tissues and cultured cells, and also promotes the formation of adventive embryos, regeneration of the plant body and production of useful substances formed by that plant.Strains of cyanobacteria or photosynthetic bacteria are preferably used as the photosynthetic procaryotic microorganism.
    Type: Grant
    Filed: February 25, 1993
    Date of Patent: April 5, 1994
    Assignees: Pentel Kabushiki Kaisha, Tadashi Matsunaga
    Inventors: Tadashi Matsunaga, Hitoshi Wake, Mayumi Ono, Kiyoshi Hishinuma, Hironori Umetsu
  • Patent number: 5217892
    Abstract: A method of plant tissue culture which comprises culturing a tissue or an organ of a plant, a part of the same or cultured cells in a medium containing a culture filtrate and/or an extract of a photosynthetic procaryotic microorganism.Such a culturing method effectively proliferates the plant tissues and cultured cells, and also promotes the formation of adventive embryos, regeneration of the plant body and production of useful substances formed by that plant.Strains of cyanobacteria or photosynthetic bacteria are preferably used as the photosynthetic procaryotic microorganism.
    Type: Grant
    Filed: July 8, 1992
    Date of Patent: June 8, 1993
    Assignees: Pentel Kabushiki Kaisha, Tadashi Matsunaga
    Inventors: Tadashi Matsunaga, Hitoshi Wake, Mayumi Ono, Kiyoshi Hishinuma, Hironori Umetsu