Patents Assigned to TAE Life Sciences, LLC
  • Borylated amino acid compositions comprising BTS and BTS(OMe) for use in boron neutron capture therapy and methods thereof
    Patent number: 11884688
    Abstract: Borylated Amino Acid compositions comprising tyrosine derivatives BTS and BTS(OMe) and novel methods of making BTS and BTS(OMe) are disclosed herein. Consequently, the BTS and/or BTS(OMe) can be scaled up to commercial scale and administered to patients as a Neutron Capture Agent and provide a method of treating cancer, immunological disorders, and other disease by utilizing a Neutron Capture Therapy modality.
    Type: Grant
    Filed: August 1, 2022
    Date of Patent: January 30, 2024
    Assignee: TAE Life Sciences, LLC
    Inventors: Michael Y. Torgov, Tioga J. Martin
  • Borylated amino acid compositions for use in boron neutron capture therapy and methods thereof
    Patent number: 11566031
    Abstract: Borylated Amino Acid (“BAA”) compositions and methods of making BAAs are disclosed herein. Consequently, the BAAs can be administered to patients as a Neutron Capture Agent and provide a method of treating cancer, immunological disorders and other disease by utilizing a Neutron Capture Therapy modality.
    Type: Grant
    Filed: March 4, 2020
    Date of Patent: January 31, 2023
    Assignee: TAE Life Sciences, LLC
    Inventors: Michael Y. Torgov, Tioga J. Martin, Arthur B. Raitano
  • Boron enriched linker (“BEL”) compositions for boron neutron capture therapy and methods thereof
    Patent number: 11219689
    Abstract: Boron Enriched Linker (“BEL”) compositions and methods of making BELs are disclosed herein. Consequently, the BELs can be conjugated to antibodies or antibody fragments to create Antibody Boron Conjugates (“ABCs”) to provide a method of treating cancer, immunological disorders and other disease by utilizing a Neutron Capture Therapy modality.
    Type: Grant
    Filed: October 10, 2019
    Date of Patent: January 11, 2022
    Assignee: TAE Life Sciences, LLC
    Inventors: Michael Y. Torgov, Tioga J. Martin
  • Biodegradable nanocarrier(s) (BPMOs) for neutron capture therapy and methods thereof
    Patent number: 11191836
    Abstract: Biodegradable Periodic Mesoporous Organosilica (BPMO) nanomaterials and methods of making BPMOs loaded with Neutron Capture Agents are disclosed herein. Consequently, the BPMOs loaded with Neutron Capture Agents provide a method of treating cancer, immunological disorders and other disease by utilizing a Neutron Capture Therapy modality.
    Type: Grant
    Filed: May 31, 2019
    Date of Patent: December 7, 2021
    Assignee: TAE Life Sciences, LLC
    Inventor: Fuhuhiko Tamanoi