Patents Assigned to Taiwan University
  • Publication number: 20250130211
    Abstract: A method of screening new psychoactive substance is provided, including providing a sample; placing the sample on chromatographic paper; ionizing the sample on the chromatographic paper by a direct analysis in real time (DART); performing a mass spectrometry analysis on the ionized sample to obtain a sample mass spectrum; and comparing a known standard mass spectrum with the sample mass spectrum, in which when a profile of the known standard mass spectrum is the same as a profile of the sample mass spectrum and the known standard mass spectrum is not exactly the same as the sample mass spectrum, the sample is determined to be the new psychoactive substance. A platform for screening new psychoactive substance is also provided to quickly screen out the new psychoactive substance.
    Type: Application
    Filed: February 8, 2024
    Publication date: April 24, 2025
    Applicant: National Taiwan University
    Inventors: Cheng-Chih Hsu, Wei-Hsin Hsu, Kai-Wen Cheng, Hsin-Bai Zou, Tzu-Hsuan Feng
  • Patent number: 12276029
    Abstract: Present invention is related to a metallic particle-deposition substrate having a metal substrate and multiple metallic particles attached thereon. The metallic particles are nano-particles with at least 90% of these nano-particles as single layer being evenly dispersed on the metal substrate. Each of the metallic particle is isolated without toughing or overlapping. The metal substrate has different material than the metallic particles in each preferred embodiment in the present invention. More preferably, at least 80% of the metallic particles have the distance between each metallic particle is at a range of 2-6 nm for better generation of hotspot effects. The present invention provides a fast production method for producing the substrate with heterogeneous interface. The metallic particles are evenly attached to the surface of the metal substrate to obtain better surface enhanced Raman effect as to apply for sensors in all kinds of field.
    Type: Grant
    Filed: May 11, 2022
    Date of Patent: April 15, 2025
    Assignee: National Taiwan University of Science and Technology
    Inventors: Bing-Joe Hwang, Wei-Nien Su, Meng-Che Tsai, Sheng-Chiang Yang
  • Patent number: 12272734
    Abstract: A semiconductor device includes a substrate, a semiconductor strip, an isolation dielectric, a plurality of channel layers, a gate structure, a plurality of source/drain structures, and an isolation layer. The semiconductor strip extends upwardly from the substrate and has a length extending along a first direction. The isolation dielectric laterally surrounds the semiconductor strip. The channel layers extend in the first direction above the semiconductor strip and arrange in a second direction substantially perpendicular to the substrate. The gate structure surrounds each of the channel layers. The source/drain structures are above the semiconductor strip and on either side of the channel layers. The isolation layer is interposed between the semiconductor strip and the gate structure and further interposed between the semiconductor strip and each of the plurality of source/drain structures.
    Type: Grant
    Filed: August 30, 2021
    Date of Patent: April 8, 2025
    Assignees: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD., National Taiwan University
    Inventors: Yu-Shiang Huang, Chee-Wee Liu
  • Publication number: 20250110133
    Abstract: Provided is a method for predicting drug efficacy of lung cancer, including providing a biological sample of a subject with lung cancer; analyzing an expression level of Leucine Zipper Down-regulated in Cancer 1; and predicting the drug efficacy based on the expression level of the Leucine Zipper Down-regulated in Cancer 1. Also provided is kit for predicting drug efficacy of lung cancer in a subject in need thereof, including an antibody against Leucine Zipper Down-regulated in Cancer 1 or a Leucine Zipper Down-regulated in Cancer 1-specific primer. Further provided is a method for treating lung cancer, including enhancing expression of Leucine Zipper Down-regulated in Cancer 1 encoded by Ldoc1 gene in a subject in need thereof.
    Type: Application
    Filed: September 26, 2024
    Publication date: April 3, 2025
    Applicants: National Health Research Institutes, National Taiwan University Hospital Hsin-Chu Branch
    Inventors: Chia-Huei Lee, Hsien-Neng Huang
  • Patent number: 12257812
    Abstract: The metallic crystal structures inspired edge-to-edge tessellations and a tessellation based lattice structures are disclosed. In accordance with an exemplary embodiment of the invention, basic unit lattice cells are stacked and connected to constitute a three-dimensional tessellations, wherein each of the basic unit lattice cells comprises a multiple flat connecting portions formed on a surface of the basic unit lattice cell and intersecting with a multiple of axes intersecting in a center of the basic unit lattice cell, and the flat connecting portions of one of the basic unit lattice cell is connected to the flat connecting portions of the adjacent basic unit lattice cell to constitute a connection structure of edge-to-edge tessellation. The formed tessellations are periodically tessellated in a design domain to form different tessellated lattice structures. The Functionally Tessellated (FT) lattice structures composed of different tessellations by interlocking into each other are also disclosed.
    Type: Grant
    Filed: February 18, 2022
    Date of Patent: March 25, 2025
    Assignee: National Taiwan University of Science and Technology
    Inventors: Chinmai Bhat, Ajeet Kumar, Jeng-Ywan Jeng
  • Patent number: 12246753
    Abstract: Various embodiments for systems and methods for cooperative driving of connected autonomous vehicles using responsibility-sensitive safety (RSS) rules are disclosed herein. The CAV system integrates proposed RSS rules with CAV's motion planning algorithm to enable cooperative driving of CAVs. The CAV system further integrates a deadlock detection and resolution system for resolving traffic deadlocks between CAVs. The CAV system reduces redundant calculation of dependency graphs.
    Type: Grant
    Filed: March 16, 2022
    Date of Patent: March 11, 2025
    Assignees: Arizona Board of Regents on Behalf of Arizona State University, National Taiwan University
    Inventors: Mohammad Khayatian, Mohammadreza Mehrabian, Harshith Allamsetti, Kai-Wei Liu, Po-Yu Huang, Chung-Wei Lin, Aviral Shrivastava
  • Patent number: 12247916
    Abstract: Provided is an identification method of plastic microparticles, including: performing an infrared analysis on plastic microparticles to identify whether the plastic microparticles include polyethylene terephthalate, polyethylene, polypropylene, or nylon 66, wherein the identification is to determine whether the plastic microparticles have a characteristic peak of each plastic, and the characteristic peak is selected from signals that do not overlap and interfere with each other in the infrared spectrum signals of each plastic.
    Type: Grant
    Filed: June 7, 2022
    Date of Patent: March 11, 2025
    Assignee: National Taiwan University
    Inventors: Chihhao Fan, Jhen-Nan Lin, Jun-Wei Li, Ya-Zhen Huang
  • Publication number: 20250076301
    Abstract: Provided is a method of accurate and sensitive characterization and prognosis of prostate cancer in a subject. The method includes obtaining a biological sample from the subject and determining the level of identified biomarkers.
    Type: Application
    Filed: September 5, 2024
    Publication date: March 6, 2025
    Applicant: National Taiwan University
    Inventors: Yeong-Shiau PU, Chung-Hsin CHEN, Pei-Wen HSIAO, Ming-Shyue LEE, Hsiang-Po HUANG, Kai-Hsiung CHANG
  • Patent number: 12237376
    Abstract: The current disclosure describes a new vertical tunnel field-effect transistor (TFET). The TFET includes a source layer over a substrate. A first channel layer is formed over the source layer. A drain layer is stacked over the first channel layer with a second channel layer stacked therebetween. The drain layer and the second channel layer overlap a first surface portion of the first channel layer. A gate structure is positioned over the channel layer by a second surface portion of the channel layer and contacts a sidewall of the second channel layer.
    Type: Grant
    Filed: December 29, 2021
    Date of Patent: February 25, 2025
    Assignees: Taiwan Semiconductor Manufacturing Co., Ltd., National Taiwan University
    Inventors: Jiun-Yun Li, Pao-chuan Shih, Wei-Chih Hou
  • Patent number: 12220436
    Abstract: An isolated bacterial strain of Lactiplantibacillus plantarum subsp. plantarum MFM 30-3 deposited under the DSMZ Accession No. DSM 34213 is provided; a probiotic composition including an Lactiplantibacillus plantarum subsp. plantarum MFM 30-3 and optionally, one or more additional probiotic organisms that enhance the probiotic activity of the Lactiplantibacillus plantarum subsp. plantarum MFM 30-3 is also provided; and a method for preventing or treating chronic kidney disease in a subject in need thereof including: administering to the subject a pharmaceutically effective amount of the probiotic composition including an isolated bacterial strain of Lactiplantibacillus plantarum subsp. plantarum MFM 30-3, and optionally, one or more additional probiotic organisms that enhance the probiotic activity of the Lactiplantibacillus plantarum subsp. plantarum MFM 30-3 is further provided.
    Type: Grant
    Filed: November 6, 2023
    Date of Patent: February 11, 2025
    Assignee: National Taiwan University
    Inventors: Ming-Ju Chen, Hsiao-Wen Huang
  • Patent number: 12217134
    Abstract: A quantum charge-coupled device including a first ion, a second ion, a fixed ion trap, an adjustable ion trap, and an excitation light source is provided. The fixed ion trap is configured to stationarily trap the first ion. The adjustable ion trap works as an ion rail disposed beside the fixed ion trap, wherein the ion rail is configured to make the second ion move at a constant velocity along the ion rail. The excitation light source is configured to irradiate an incident light beam. The incident light beam includes a series of light pulses and covers the first ion and the second ion when a distance between them becomes less than or equal to a proximity range, such that a quantum entangled state is directly built between the first ion and the second ion in uniform motion.
    Type: Grant
    Filed: November 24, 2022
    Date of Patent: February 4, 2025
    Assignee: National Taiwan University
    Inventors: Guin-Dar Lin, Wen-Han Png
  • Publication number: 20250032015
    Abstract: A blood physiological parameter sensing device includes a housing, a flow channel structure, a control unit and a sensing unit. The flow channel structure is disposed in the housing and forms a channel for a liquid to be measured to pass. The control unit is disposed in the housing. The sensing unit is disposed in the housing, is electrically connected to the control unit, and has a sensing end. The sensing end passes through the flow channel structure, is configured in the channel, and has an electrochemical sensing material. The electrochemical sensing material is used to exchange electrons with the blood physiological parameter in the liquid to be measured to produce redox reactions to generate current or voltage change parameters. The sensing unit transmits the current or voltage change parameters to the control unit, which obtains a blood physiological parameter concentration value to achieve instantaneous and continuous monitor the patients.
    Type: Application
    Filed: July 22, 2024
    Publication date: January 30, 2025
    Applicants: National Taiwan University, National Taiwan University Hospital Hsin-Chu Branch, National Yang Ming Chiao Tung University
    Inventors: Yih-Sharng CHEN, Hsiao-En TSAI, Yu-Ting CHENG
  • Publication number: 20250030162
    Abstract: The present invention is a reconfigurable antenna, which includes a total reflection part, a partial reflection part, a partial transmission part, and a radiation part stacked in sequence. A resonant cavity is formed between the partial reflection part and the total reflection part. The radiation part is arranged in the resonant cavity. So that the electromagnetic wave radiated by the radiation part is reflected in the resonant cavity. The electromagnetic wave forms constructive interference during the reflection of the resonant cavity. The resonant cavity makes the electromagnetic wave form the same phase electromagnetic wave and radiation penetrating the reflection part. The partial transmission part is regulated to form beam reconstruction conditions, and the same-phase electromagnetic waves are formed into beams and radiated into space by the beam control conditions.
    Type: Application
    Filed: July 19, 2023
    Publication date: January 23, 2025
    Applicant: National Taiwan University
    Inventors: Yi-Cheng LIN, Ching-Mei WANG, Chang-Kai LAI
  • Patent number: 12206148
    Abstract: The invention discloses a filter device. The filter device comprises a substrate, at least one transmission conductor, and a reference conductor having a slotted structure. The substrate is provided at a first surface thereof with the transmission conductor, and provided at a second surface thereof with the reference conductor. The slotted structure comprises a frame portion, a slotted portion, and a hollow portion. The slotted portion surrounds the frame portion, and the hollow portion is formed in the frame portion. At least one impedance unit is configured on the frame portion. The equivalent filter circuit of the filter device is formed between the transmission conductor, the slotted structure, the reference conductor, and the impedance unit. Thereby, the equivalent filter circuit absorbs at least one noise at at least one specific frequency by the impedance unit to avoid the noise reflected to affect the transmission quality of signal.
    Type: Grant
    Filed: December 10, 2021
    Date of Patent: January 21, 2025
    Assignee: National Taiwan University
    Inventors: Tzong-Lin Wu, Hsu-Wei Liu, Chi-Hsuan Cheng, Po-Jui Li
  • Patent number: 12198305
    Abstract: The present disclosure relates to a data processing method, and more specifically, to a digital image processing method to enable a rapid noise-suppressed contrast enhancement in an optical linear or nonlinear microscopy imaging application. The disclosed method digitally mimics a hardware-based feedback-driven adaptive or controlled illumination technique by means of digitally resembling selective laser-on and laser-off states so as to selectively optimize the signal strength and hence the visibility of the weak-intensity morphologies while mostly preventing saturation of the brightest structures.
    Type: Grant
    Filed: May 30, 2022
    Date of Patent: January 14, 2025
    Assignee: National Taiwan University
    Inventors: Chi-Kuang Sun, Bhaskar Jyoti Borah
  • Patent number: 12188862
    Abstract: A microscope is provided to measure HbA1c fraction. The microscope measures the HbA1c fraction of a single red blood cell (RBC) in a trace blood sample. The HbA1c fraction can be measured through a non-invasive way while the RBC flows in a human epidermal microvessel, too. The microscope comprises a laser device, an upright microscope, a light splitter, a light detector, and a mainframe. Unlike traditional methods, the HbA1c fraction can be measured in vitro or in vivo at the level of a single RBC. Accurate measurement is achieved. Misdiagnosis rate is reduced. The microscope provides HbA1c fractions from hundreds of RBCs, instead of averaging HbA1c fractions obtained from a large number of blood samples. Hence, the present invention is a method of detecting a HbA1c fraction of a single RBC, and is a microscope supporting blood-drawing measurement and non-invasive measurement simultaneously.
    Type: Grant
    Filed: February 24, 2023
    Date of Patent: January 7, 2025
    Assignee: National Taiwan University
    Inventors: Chi-Kuang Sun, Xu-hao Ye
  • Publication number: 20250007179
    Abstract: Disclosed are a dual-polarization cavity-backed antenna, a package module and an array package module. The antenna includes a substrate, a magnetic current feeding structure, an electric current feeding structure, and a cavity-backed structure that is arranged between two surfaces of the substrate. The magnetic current feeding structure and the electric current feeding structure transfer energy into the cavity-backed structure, respectively radiating the orthogonally polarized electromagnetic wave. The electric field direction of the first electromagnetic wave and the magnetic field direction of the second electromagnetic wave occur on the same plane. The package module includes the dual-polarization cavity-backed antenna, a radio frequency control chip, and a control circuit unit. The array package module includes a plurality of the dual-polarization cavity-backed antennas, a radio frequency control unit including a single RF chip or chip set, and a control circuit unit.
    Type: Application
    Filed: June 29, 2023
    Publication date: January 2, 2025
    Applicant: National Taiwan University
    Inventors: Yi-Cheng LIN, Tzu-Ming HUANG
  • Patent number: 12160998
    Abstract: The disclosure is directed to spin-orbit torque MRAM structures and methods. A SOT channel of the SOT-MRAM includes multiple heavy metal layers and one or more dielectric dusting layers each sandwiched between two adjacent heavy metal layers. The dielectric dusting layers each include discrete molecules or discrete molecule clusters of a dielectric material scattered in or adjacent to an interface between two adjacent heavy metal layers.
    Type: Grant
    Filed: July 22, 2022
    Date of Patent: December 3, 2024
    Assignees: Taiwan Semiconductor Manufacturing Co., Ltd., National Taiwan University
    Inventors: Zong-You Luo, Ya-Jui Tsou, I-Cheng Tung, CheeWee Liu
  • Patent number: 12157267
    Abstract: A large area deposition type additive manufacturing equipment is disclosed. The large area deposition type additive manufacturing equipment includes a light source module, a dynamic photomask module, a raw material tank and a deposition module. The light source module includes a plurality of light emitting members, a light diffusion member, a light enhancement member and a light emitting angle limiter. Light emitted from the light emitting members passes through the light diffusion member, the light enhancement member and the light emitting angle limiter to become a collimated curing light. The collimated curing light travels through a transparent member of the raw material tank and a dynamic photomask module to reach liquid photocurable material in the raw material tank, thereby curing the liquid photocurable material. The angle of emitted light ranges within ±30° with respect to a normal line of an incident plane of the light source module.
    Type: Grant
    Filed: May 29, 2022
    Date of Patent: December 3, 2024
    Assignee: National Taiwan University of Science and Technology
    Inventors: Jeng-Ywan Jeng, Ding-Zheng Lin, Ping-Hung Yu, Yu-Cheng Chen
  • Publication number: 20240397621
    Abstract: A circuit board device includes a transition region that includes a first conductive layer at a first level, a second conductive layer at a second level, and conductive vias. The first conductive layer includes a pad connected to the solderless connector, a transmission line, and a first reference layer. The transmission line includes first and second segments. A second width of the second segment is the same as or less than a first width of the first segment. The first reference layer has a first anti-pad region for the pad and the transmission line disposed therein. In a plan view, the first anti-pad region surrounding the pad is completely located within a second anti-pad region of a second reference layer of the second conductive layer. The conductive vias are disposed between the first and second conductive layers and surround the pad.
    Type: Application
    Filed: June 30, 2023
    Publication date: November 28, 2024
    Applicants: UNIMICRON TECHNOLOGY CORP., National Taiwan University
    Inventors: Chin-Hsun WANG, Ruey-Beei WU, Chun-Jui HUANG, Wei-Yu LIAO, Ching-Sheng CHEN, Chi-Min CHANG