Abstract: The present disclosure relates to a Taraxacum Coreanum phytoplacenta cell culture extract that has moisturizing and soothing effects for extremely dry skin such as atopic dermatitis, and skin barrier strengthening effect. The Taraxacum Coreanum phytoplacenta cell culture or an extract thereof according to the present disclosure is non-toxic to skin cells, and has an efficacy of moisturizing, anti-aging, strengthening the skin barrier, improving wrinkles, soothing the skin, protecting the skin from UV rays, and protecting the skin from blue light, etc.