Abstract: To provide a medical sheet with which a surface (a portion) subjected to ion bombardment, and a surface (a portion) which has not been subjected to ion bombardment can be distinguished from each other; and a production method therefor. When ?b refers to the difference between value b1, which is the b value of a roughened surface portion 3, and value b2, which is the b value of a second surface 7, this medical sheet has a ?b in the range of 1.5-11 inclusive. A production method for the medical sheet includes: a surface roughening step in which a portion or the entirety of a first surface 5 of a sheet including polytetrafluoroethylene is subjected to surface roughening treatment to form a roughened surface portion 5; and a heating step in which the sheet which includes the polytetrafluoroethylene and which has undergone the surface roughening step is heated to obtain the medical sheet.