Patents Assigned to Tambo, Inc.
  • Processes for preparing functionalized cyclooctenes
    Patent number: 12194100
    Abstract: The present disclosure relates to processes for preparing functionalized cyclooctenes and the synthetic intermediates prepared thereby.
    Type: Grant
    Filed: October 10, 2019
    Date of Patent: January 14, 2025
    Assignees: Tambo, Inc., The Research Foundation of the State University of New York
    Inventors: Jose M. Mejia Oneto, Nathan Yee, Jochem Theodoor Van Herpt, Chun-Min Zeng, Da-Ming Gou, Maksim Royzen
  • Bioorthogonal compositions
    Patent number: 11253600
    Abstract: Cyclooctene conjugates of therapeutic or diagnostic agents have improved aqueous solubility and can release the agents upon contact with a tetrazine-containing biomaterial. The cyclooctene conjugates provide site-selective delivery of agents at the location of the tetrazine-containing biomaterial in a subject. The compositions and methods have applications in the treatment of various diseases or conditions including cancer, tumor growths, and bacterial infections.
    Type: Grant
    Filed: April 6, 2018
    Date of Patent: February 22, 2022
    Assignees: TAMBO, INC., THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: Jose Manuel Mejia Oneto, Nathan Yee, Maksim Royzen, Sangeetha Srinivasan, Ethan Miller
  • Bioorthogonal compositions
    Patent number: 10828373
    Abstract: The present disclosure provides bioorthogonal compositions for delivering agents in a subject. The disclosure also provides methods of producing the compositions, as well as methods of using the same.
    Type: Grant
    Filed: September 12, 2016
    Date of Patent: November 10, 2020
    Assignee: Tambo, Inc.
    Inventors: Jose Mejia Oneto, Robert Galemmo, Jr.