Patents Assigned to TANDEM DIAGNOSTICS, INC.
  • ASSAY SYSTEMS FOR GENETIC ANALYSIS
    Publication number: 20130004950
    Abstract: The present invention provides assays systems and methods for detection of chromosomal abnormalities and status of single loci associated with monogenic or polygenic traits in a sample containing nucleic acids from a maternal and a fetal source.
    Type: Application
    Filed: November 10, 2011
    Publication date: January 3, 2013
    Applicant: Tandem Diagnostics, Inc.
    Inventors: Andrew Sparks, Arnold Oliphant, Jacob Zahn, Ken Song, John Stuelpnagel
  • ENHANCED RISK PROBABILITIES USING BIOMOLECULE ESTIMATIONS
    Publication number: 20120190018
    Abstract: The present invention provides processes for determining more accurate risk probabilities for medical conditions. The risk probabilities of the presence or absence of a medical condition are calculated using frequency data from selected biomolecules and biomolecule source contribution of at least one source in a mixed sample.
    Type: Application
    Filed: October 15, 2011
    Publication date: July 26, 2012
    Applicant: Tandem Diagnostics, Inc.
    Inventors: Craig Struble, Eric Wang, Andrew Sparks, Arnold Oliphant
  • DETECTION OF GENETIC ABNORMALITIES AND INFECTIOUS DISEASE
    Publication number: 20120077185
    Abstract: The present invention provides assay systems and related methods for detecting genetic abnormalities and infectious agents in maternal samples. Exemplary maternal samples for analysis using the assay systems of the invention include maternal blood, plasma or serum.
    Type: Application
    Filed: September 26, 2011
    Publication date: March 29, 2012
    Applicant: Tandem Diagnostics, Inc.
    Inventors: Arnold Oliphant, Andrew Sparks, Jacob Zahn, John Stuelpnagel, Ken Song
  • ASSAY SYSTEMS FOR GENETIC ANALYSIS
    Publication number: 20120040859
    Abstract: The present invention provides assays systems and methods for detection of chromosomal abnormalities and status of single loci associated with monogenic or polygenic traits in a sample containing nucleic acids from a maternal and a fetal source.
    Type: Application
    Filed: August 8, 2011
    Publication date: February 16, 2012
    Applicant: Tandem Diagnostics, Inc.
    Inventors: Andrew Sparks, Arnold Oliphant, Jacob Zahn, Ken Song, John Stuelpnagel
  • ASSAY SYSTEMS FOR DETERMINATION OF SOURCE CONTRIBUTION IN A SAMPLE
    Publication number: 20120034685
    Abstract: The present invention provides assay systems and methods for detection of copy number variation at one or more loci and polymorphism detection at one or more loci in a mixed sample from an individual.
    Type: Application
    Filed: August 8, 2011
    Publication date: February 9, 2012
    Applicant: TANDEM DIAGNOSTICS, INC.
    Inventors: Andrew Sparks, Craig Struble, Eric Wang, Arnold Oliphant
  • LIGATION-BASED DETECTION OF GENETIC VARIANTS
    Publication number: 20120034603
    Abstract: The present invention provides assays systems and methods for detection of genetic variants in a sample, including copy number variation and single nucleotide polymorphisms. The invention preferably employs the technique of tandem ligation, i.e. the ligation of two or more fixed sequence oligonucleotides and one or more bridging oligonucleotides complementary to a region between the fixed sequence oligonucleotides.
    Type: Application
    Filed: January 25, 2011
    Publication date: February 9, 2012
    Applicant: TANDEM DIAGNOSTICS, INC.
    Inventors: Arnold Oliphant, Andrew Sparks, John Stuelpnagel, Ken Song