Abstract: A micro-organ specificity maintenance system includes a micro-organ specificity parallel reactor module for storing and culturing vascularized micro-organs; a feeding module for feeding culture solutions to the micro-organ specificity parallel reactor module; an injection module for injecting medical solutions containing traditional Chinese medicine micromolecules into the micro-organ specificity parallel reactor module; a micro-organ circulation coupling module for transmitting venous flow and arterial flow to the micro-organ specificity parallel reactor module; and a micro-organ neural coupling module for transmitting neural network signals to the micro-organ specificity parallel reactor module. The micro-organ specificity maintenance system provided in the disclosure has the advantage that an extracorporeal circulation system and internal vascular systems of complex organs are organically integrated and connected.

Abstract: A transdermal double-layer microneedle based on hydrogen producing probiotics and its preparation method and application thereof are provided. The transdermal double-layer microneedle consists of a needle body and a backing layer. The raw material of the needle body includes hyaluronic acid and hyaluronidase. The raw material of the backing layer includes methacrylate anhydride gelatin and silk fibroin protein. The hydrogen producing bacteria are loaded in the microneedles, and the pore size of the matrix material is lower than the diameter of the probiotics, which will not lead to the leakage of bacteria and has high safety. Treatment of inflammatory skin diseases by gas has low side effects. The needle tip is loaded with hyaluronidase to increase the tissue space and improve the effect of gas treatment. It is expected to be used in psoriasis and other inflammatory skin diseases.

Abstract: A probiotic microcapsule for the treatment of reproductive tract infection and a preparation method and application thereof are provided. The probiotic microcapsule is obtained by coating probiotics with the coating material. The probiotics include one or several of Lactobacillus acidophilus, Lactobacillus rhamnosus, Lactobacillus fermentum, Lactobacillus reuteri, Lactobacillus crimpus, Lactobacillus brevis, Lactobacillus salivary, Lactobacillus plantarum, Lactobacillus acidophilus, and Lactobacillus bulgaricus. As probiotics screened in reproductive tract, it has high safety; It endows probiotics with adhesion function to ensure their effect in the reproductive tract; It overcomes the defects of current antibiotic therapy; It is expected to be used in a variety of reproductive tract infectious diseases.

Abstract: A multi-micro-organ culture and interaction big data analysis system based on cloud native includes a multi-micro-organ culture database, a learning model establishment module, a feature extraction terminal, a multi-micro-organ visualization terminal and a multi-micro-organ learning terminal, the multi-micro-organ culture database is connected to the learning model establishment module by means of a signal line, the learning model establishment module is connected to the feature extraction terminal by means of a signal line, the feature extraction terminal is connected to the multi-micro-organ visualization terminal and the multi-micro-organ learning terminal separately by means of signal lines, and the feature extraction terminal includes a micro-organ function extraction module, a micro-organ interaction extraction module and a medicine response extraction module.

Abstract: A multi-micro-organ system data processing system based on a field programmable gate array includes a data collection module, a programmable processing terminal, a server and a display terminal, the data collection module is connected to the programmable processing terminal by means of a signal line, the programmable processing terminal is connected to the server, the server is connected to the display terminal, and the programmable processing terminal includes a data processing chip, a file management module, a cache module, a high-speed transmission module, a safety protection module and a fault alarm module. According to the disclosure, flow data, temperature data, CO2 concentration data, cell activity data, functional index data and electroencephalogram signals can be synchronously collected, quickly processed, and then cached and transmitted at a high speed, so as to obviously improve data processing efficiency.

Abstract: A multi-micro-organ extracorporeal circulation and neural network maintenance system, includes a plurality of organ specificity maintenance systems, and each independent organ specificity maintenance system is connected to a human brain organ specificity maintenance system and a heart organ specificity maintenance system in a two-way manner by means of a simulated neural network.