Abstract: Disclosed are immunogens and peptides based on the binding site of gClq-R for HIV-1 gp120, and immunogens and peptides based on the binding site of HIV-1 gp120 for gClq-R. The sequence of the gClq-R binding site for gp120 is shown in SEQ ID NO.: 2. The sequence of the HIV-1 gp120 binding site for gClq-R is shown in SEQ ID NO.: 3. Also disclosed are antibodies and binding molecules to all such immunogens and peptides, and inducing the endogenous production of such antibodies.
Type:
Grant
Filed:
September 6, 1996
Date of Patent:
March 24, 1998
Assignee:
Tanux Biosystems, Inc.
Inventors:
Michael S. C. Fung, Bill N. C. Sun, Cecily R. Y. Sun, Young Woo Kim, Liming Yu