Patents Assigned to TaP Pharmaceuticals AG
  • Liquid pharmaceutical formulations of tafamidis
    Patent number: 11980685
    Abstract: Certain embodiments of the present disclosure provide liquid pharmaceutical formulations, suitable for oral administration, that contain an amount of a tafamidis of from 0.5 mg/ml to 20 mg/ml, water, and an amount of an alkaline pH modifier that yields a content of the tafamidis solubilized in the water of from 0.5 mg/ml to 19.8 mg/ml.
    Type: Grant
    Filed: December 23, 2022
    Date of Patent: May 14, 2024
    Assignee: TaP Pharmaceuticals, AG
    Inventors: Nilesh Parikh, William Hite
  • Pharmaceutical formulations of tafamidis
    Patent number: 11878081
    Abstract: Certain embodiments of the present disclosure provide pharmaceutical, unit-dose formulations, suitable for oral administration, that contain from 1% w/w to 20% w/w of a tafamidis-organic acid (such as adipic acid, glutaric acid, or fumaric acid) co-crystal; from 0.25% w/w to 2.5% w/w of an organic acid dissolution enhancer. Such formulations release, within 15 minutes in ¾ strength FeSSIF pH 5.8 or in FaSSIF+0.1% polysorbate 80 pH 6.5, at least 85% of the total tafamidis of the formulation.
    Type: Grant
    Filed: December 23, 2022
    Date of Patent: January 23, 2024
    Assignee: TaP Pharmaceuticals AG
    Inventors: Nilesh Parikh, William Hite
  • Liquid pharmaceutical formulations of apixaban
    Patent number: 11833138
    Abstract: Certain embodiments of the present disclosure provide liquid pharmaceutical formulations, suitable for oral administration, that contain glycerol and an amount of apixaban in the solution phase of the formulations of from 0.5 mg/ml to 6 mg/ml.
    Type: Grant
    Filed: January 30, 2023
    Date of Patent: December 5, 2023
    Assignee: TaP Pharmaceuticals AG
    Inventors: Nilesh Parikh, William Hite