Abstract: A method of enhancing an immune response to an antigen is provided. The method involves augmenting the level of a TAP molecule in a target cell bearing the antigen. Preferably, the TAP molecules enhanced by administering a nucleic acid sequence encoding a TAP-1 and/or TAP-2 molecule. The method is useful in treating infectious diseases and cancer.
Type:
Application
Filed:
February 11, 2008
Publication date:
April 1, 2010
Applicant:
Taplmmune, Inc.
Inventors:
Wilfred Arthur Jefferies, Qian-Jin Zhang, Susan Shu-Ping Chen, Judie Barbara Alimonti