Patents Assigned to Target Therapeutics, Inc.
  • Patent number: 8317772
    Abstract: A catheter comprising an elongate tubular member having a proximal end, a distal end, and a passageway defining a lumen extending between the proximal and distal ends. The elongate tubular member comprises a relatively stiff proximal section and a relatively flexible distal section. The proximal section includes an inner tubular liner, a first stiffener comprising a metal alloy, and a second stiffener comprising a non-metal alloy. The first and second stiffeners are coaxially wound exterior to the proximal inner liner. The distal section includes a distal inner tubular liner and the second stiffener coaxially wound exterior to the distal inner liner. The first stiffener terminates before reaching the distal section.
    Type: Grant
    Filed: March 10, 2011
    Date of Patent: November 27, 2012
    Assignee: Target Therapeutics, Inc.
    Inventors: Lex P. Jansen, Thomas Yung-Hui Chien, Perry Alvin Fukui, Jeffrey A. Sarge, Lawrence Charles Alpert
  • Patent number: 8181324
    Abstract: A catheter section comprising an elongate tubular member having a proximal end, a distal end, and a passageway defining a lumen extending between the proximal and distal ends. The elongate tubular member includes a knit tubular member and an inner tubular liner in coaxial relationship with the knit tubular member. The catheter section is for use as a distal section in a catheter having a relatively stiff proximal section.
    Type: Grant
    Filed: October 18, 2010
    Date of Patent: May 22, 2012
    Assignee: Target Therapeutics, Inc.
    Inventors: Jill M. McFadden, Earl Bardsley, Robert Garabedian
  • Publication number: 20110172643
    Abstract: A catheter comprising an elongate tubular member having a proximal end, a distal end, and a passageway defining a lumen extending between the proximal and distal ends. The elongate tubular member comprises a relatively stiff proximal section and a relatively flexible distal section. The proximal section includes an inner tubular liner, a first stiffener comprising a metal alloy, and a second stiffener comprising a non-metal alloy. The first and second stiffeners are coaxially wound exterior to the proximal inner liner. The distal section includes a distal inner tubular liner and the second stiffener coaxially wound exterior to the distal inner liner. The first stiffener terminates before reaching the distal section.
    Type: Application
    Filed: March 10, 2011
    Publication date: July 14, 2011
    Applicant: TARGET THERAPEUTICS, INC.
    Inventors: Lex P. Jansen, Thomas Yung-Hui Chien, Perry Alvin Fukui, Jeffrey A. Sarge, Lawrence Charles Alpert
  • Publication number: 20110144625
    Abstract: This is a composite guidewire for use with a catheter for accessing a targeted site in a lumen system of a patient's body. The guidewire core or guidewire section may be of a stainless steel or a high elasticity metal alloy, preferably a Ni—Ti alloy, also preferably having specified physical parameters. The composite guidewire assembly is especially useful for accessing peripheral or soft tissue targets. The invention includes multi-section guidewire assemblies having super-elastic alloy or stainless steel ribbon braided reinforcements along a least a portion of the core. A variation of the inventive guidewire includes a braid and a tie layer (and one or more lubricious polymers on the tie layer exterior) to enhance the guidewire's suitability for use within catheters and within the interior of vascular lumen.
    Type: Application
    Filed: February 7, 2011
    Publication date: June 16, 2011
    Applicant: TARGET THERAPEUTICS, INC.
    Inventors: Gregory E. Mirigian, Harold F. Carrison, Laurent Schaller, Erik T. Engelson
  • Publication number: 20110082493
    Abstract: This is a surgical device usually delivered through an intravascular catheter. It may be used in several ways. It may, for instance, be used to open a clear passageway adjacent thrombus to allow both blood and medication to bypass the clot. It may be used to pierce and to remove thrombus. These thrombus are often found in tortuous vasculature. The device includes several sections. The device has a core element, typically a core wire. Placed around the distal end of the core element is a collapsible but preferably self expanding proximal cage assembly and a distal filter, preferably a self-expanding cage assembly or other filter component. The various portions of those components are preferably radio-opaque. The proximal end of the proximal cage is typically is affixed to an actuator in such a way as to allow expansion of the cage after deployment.
    Type: Application
    Filed: December 13, 2010
    Publication date: April 7, 2011
    Applicant: TARGET THERAPEUTICS, INC.
    Inventors: Gene Samson, Harold F. Carrison
  • Patent number: 7909812
    Abstract: A catheter comprising an elongate tubular member having a proximal end, a distal end, and a passageway defining a lumen extending between the proximal and distal ends. The elongate tubular member comprises a relatively stiff proximal section and a relatively flexible distal section. The proximal section includes an inner tubular liner, a first stiffener comprising a metal alloy, and a second stiffener comprising a non-metal alloy. The first and second stiffeners are coaxially wound exterior to the proximal inner liner. The distal section includes a distal inner tubular liner and the second stiffener coaxially wound exterior to the distal inner liner. The first stiffener terminates before reaching the distal section.
    Type: Grant
    Filed: September 6, 2006
    Date of Patent: March 22, 2011
    Assignee: Target Therapeutics, Inc.
    Inventors: Lex P. Jansen, Thomas Yung-Hui Chien, Perry Alvin Fukui, Jeffrey A. Sarge, Lawrence Charles Alpert
  • Patent number: 7883474
    Abstract: This is a composite guidewire for use with a catheter for accessing a targeted site in a lumen system of a patient's body. The guidewire core or guidewire section may be of a stainless steel or a high elasticity metal alloy, preferably a Ni—Ti alloy, also preferably having specified physical parameters. The composite guidewire assembly is especially useful for accessing peripheral or soft tissue targets. The invention includes multi-section guidewire assemblies having super-elastic alloy or stainless steel ribbon braided reinforcements along a least a portion of the core. A variation of the inventive guidewire includes a braid and a tie layer (and one or more lubricious polymers on the tie layer exterior) to enhance the guidewire's suitability for use within catheters and within the interior of vascular lumen.
    Type: Grant
    Filed: April 30, 1996
    Date of Patent: February 8, 2011
    Assignee: Target Therapeutics, Inc.
    Inventors: Gregory E. Mirigian, Harold E. Carrison, Laurent Schaller, Erik T. Engelson
  • Publication number: 20110024025
    Abstract: A catheter section comprising an elongate tubular member having a proximal end, a distal end, and a passageway defining a lumen extending between the proximal and distal ends. The elongate tubular member includes a knit tubular member and an inner tubular liner in coaxial relationship with the knit tubular member. The catheter section is for use as a distal section in a catheter having a relatively stiff proximal section.
    Type: Application
    Filed: October 18, 2010
    Publication date: February 3, 2011
    Applicant: TARGET THERAPEUTICS, INC.
    Inventors: Jill M. McFadden, Earl Bardsley, Robert Garabedian
  • Patent number: 7875050
    Abstract: An embolism treatment device includes an elongated core wire having a coil tip coupled to the distal end of the core wire and a cage assembly substantially coaxial to the core wire, having a first deployment shape and a second expanded shape. The core wire is freely moveable axially through the cage assembly. The device additionally includes an inner coil surrounding the core wire within the cage assembly and an actuator element, having a first position and a second position, located proximally to the cage assembly, wherein when the actuator element is in the first position, the cage assembly is in the first deployment shape and when the actuator element is in the second position, the cage assembly is in the second expanded shape.
    Type: Grant
    Filed: February 22, 2002
    Date of Patent: January 25, 2011
    Assignee: Target Therapeutics, Inc.
    Inventors: Gene Samson, Harold F Carrison
  • Patent number: 7815626
    Abstract: A catheter section comprising an elongate tubular member having a proximal end, a distal end, and a passageway defining a lumen extending between the proximal and distal ends. The elongate tubular member includes a knit tubular member and an inner tubular liner in coaxial relationship with the knit tubular member. The catheter section is for use as a distal section in a catheter having a relatively stiff proximal section.
    Type: Grant
    Filed: June 12, 1998
    Date of Patent: October 19, 2010
    Assignee: Target Therapeutics, Inc.
    Inventors: Jill M. McFadden, Earl Bardsley, Robert Garabedian
  • Patent number: 7104979
    Abstract: A catheter comprising an elongate tubular member having a proximal end, a distal end, and a passageway defining a lumen extending between the proximal and distal ends. The elongate tubular member comprises a relatively stiff proximal section and a relatively flexible distal section. The proximal section includes an inner tubular liner, a first stiffener comprising a metal alloy, and a second stiffener comprising a non-metal alloy. The first and second stiffeners are coaxially wound exterior to the proximal inner liner. The distal section includes a distal inner tubular liner and the second stiffener coaxially wound exterior to the distal inner liner. The first stiffener terminates before reaching the distal section.
    Type: Grant
    Filed: February 19, 2002
    Date of Patent: September 12, 2006
    Assignee: Target Therapeutics, Inc.
    Inventors: Lex P. Jansen, Thomas Yung-Hui Chien, Perry Alvin Fukui, Jeffrey A. Sarge, Lawrence Charles Alpert
  • Patent number: 6984240
    Abstract: A vasoocclusive helical coil having a proximal end that carries a coupling member for attaching the coil to the distal end of a wire and a proximal winding that has a smaller diameter than adjacent windings whereby the proximal end of the coil is positioned radially inwardly of the main body of the coil.
    Type: Grant
    Filed: October 25, 1996
    Date of Patent: January 10, 2006
    Assignee: Target Therapeutics, Inc.
    Inventors: Christopher G. M. Ken, Abhijit Acharya
  • Publication number: 20050033350
    Abstract: A vasoocclusive helical coil having a proximal end that carries a coupling member for attaching the coil to the distal end of a wire and a proximal winding that has a smaller diameter than adjacent windings whereby the proximal end of the coil is positioned radially inwardly of the main body of the coil.
    Type: Application
    Filed: August 31, 2004
    Publication date: February 10, 2005
    Applicant: Target Therapeutics, Inc.
    Inventors: Christopher Ken, Abhijit Acharya
  • Patent number: 6824553
    Abstract: This is a catheter assembly and a section of that catheter assembly. That catheter assembly may be used in accessing a tissue target within the body, typically a target which is accessible through the vascular system. Central to the invention is the use of a braided metallic reinforcing member, typically of super-elastic alloy ribbon, situated within the catheter body in such a way to create a catheter having an exceptionally thin wall, controlled stiffness, high resistance to kinking, and complete recovery in vivo from kinking situations. The braid may have a single pitch or may vary in pitch along the axis of the catheter or catheter section. The braided ribbon reinforcing member typically is placed between a flexible outer tubing member and an inner tubing member to produce a catheter section which is very flexible but highly kink resistant.
    Type: Grant
    Filed: August 25, 2000
    Date of Patent: November 30, 2004
    Assignee: Target Therapeutics, Inc.
    Inventors: Gene Samson, Uriel Hiram Chee, Kim Nguyen, Edward J. Snyder, Erik T. Engelson
  • Patent number: 6706025
    Abstract: This invention is in the general field of surgical instruments. It relates specifically to catheters which may be used in cardiovascular and endovascular procedures to deliver diagnostic, therapeutic, or vaso-occlusive agents to a target site within a human or animal body which is accessible by a system of natural passageways within that body. The catheters are coated in such a way that they are exceptionally slippery and the coating is very durable. The invention also relates to methods of coating the catheters and to methods of applying lubricious coatings.
    Type: Grant
    Filed: February 28, 2001
    Date of Patent: March 16, 2004
    Assignee: Target Therapeutics, Inc.
    Inventors: Erik T. Engelson, Robert Hergenrother, Joseph Eder
  • Patent number: 6660020
    Abstract: This is an implantable vaso-occlusive coil which is implanted using minimally invasive surgical techniques. It is a complex, helically wound coil made up of a primary helically wound coil which is then wound into a specific secondary shape. The secondary shape is itself a series of helical turns. At least a portion of the turns in the secondary shape form a cylindrical region and adjacent that region on at least one end is a conical region which tapers from a diameter approximating that of the central cylindrical region to a smaller diameter. The device is desirably self-forming upon exit from the distal end of a delivery catheter. Also, the conical tipped vaso-occlusive device may also utilize thrombus-enhancing filamentary material.
    Type: Grant
    Filed: November 4, 1999
    Date of Patent: December 9, 2003
    Assignee: Target Therapeutics, Inc.
    Inventors: Michael P. Wallace, Francisco S. Villar, Nga Thi Van, Nestor Aganon, Delilah Yin Hui
  • Patent number: 6638243
    Abstract: This is a medical catheter made up of a body having on its distal end portion an expandable balloon and, proximal of the balloon, a delivery lumen ending in a port through which therapeutic or diagnostic agents may be delivered. In one variation, a single inflation/wire lumen extends from the catheter proximal end to the catheter distal end, through which the balloon is inflated with pressurized fluid and through which a guide wire extends. The guide wire may have a valve plug for selectively seating against a valve seat of the catheter distal end to seal the inflation/wire lumen for balloon inflations. In another variation, a vaso-occlusive agent is disposable within a delivery lumen in a catheter coupled with a steerable guidewire. The delivery lumen ends in a delivery port near to and proximal of an expandable balloon located at the catheter's end. A single inflation/wire lumen may also be provided for facilitating both balloon inflation and guide wire tracking.
    Type: Grant
    Filed: August 2, 2002
    Date of Patent: October 28, 2003
    Assignee: Target Therapeutics, Inc.
    Inventor: David Kupiecki
  • Patent number: 6623493
    Abstract: This device is an apparatus for endovascular occlusion through the formation of thrombi in arteries, veins, aneurysms, vascular malformations, and arteriovenous fistulas. In particular, the device includes multiple vaso-occlusive members connected by electrolytically disintegratible links. Each link connects to the vaso-occlusive member by electrically insulative and conductive joints on opposite ends of the link. The vaso-occlusive members are delivered through a delivery catheter having on its distal end an electrode for electrical contact with the vaso-occlusive member. Upon application of an electrical current through the electrode to the vaso-occlusive member and its conductive joint to the electrolytically disintegratible link, the link disintegrates, selectively detaching the desired number of vaso-occlusive members into the target thrombus formation site.
    Type: Grant
    Filed: August 24, 2001
    Date of Patent: September 23, 2003
    Assignee: Target Therapeutics, Inc.
    Inventors: Michael P. Wallace, Chad C. Roue
  • Publication number: 20030130689
    Abstract: This device is an apparatus for endovascular occlusion through the formation of thrombi in arteries, veins, aneurysms, vascular malformations, and arteriovenous fistulas. In particular, the device includes multiple vaso-occlusive members connected by electrolytically disintegratible links. Each link connects to the vaso-occlusive member by electrically insulative and conductive joints on opposite ends of the link. The vaso-occlusive members are delivered through a delivery catheter having on its distal end an electrode for electrical contact with the vaso-occlusive member. Upon application of an electrical current through the electrode to the vaso-occlusive member and its conductive joint to the electrolytically disintegratible link, the link disintegrates, selectively detaching the desired number of vaso-occlusive members into the target thrombus formation site.
    Type: Application
    Filed: February 18, 2003
    Publication date: July 10, 2003
    Applicant: Target Therapeutics, Inc.
    Inventors: Michael P. Wallace, Chad C. Roue
  • Patent number: 6589230
    Abstract: A solderless sacrificial link between a detachable member which is placed at and is intended to remain at a desired site within the mammalian body and the core wire used to introduce the detachable member. The detachable member device may be one used to create emboli in the vascular system or may be of any other type deliverable into the human body and detached into an ionic aqueous environment, either for later removal or permanent placement.
    Type: Grant
    Filed: October 27, 1999
    Date of Patent: July 8, 2003
    Assignee: Target Therapeutics, Inc.
    Inventors: Son Gia, Hong Doan, Pete Phong Pham, Ivan Sepetka, U. Hiram Chee, Michael Mariant, David Kupiecki