Abstract: Provided herein is a fungicidal composition, comprising a pharmaceutically effective amount of a phosphorylcholine-tuftsin conjugate, and optionally comprising a pharmaceutically acceptable carrier. A method of using the fungicidal composition such as for treating or preventing a disease or disorder associated with fungal infection in a subject in need thereof is also provided. Furthermore, method of using the fungicidal composition such as for enhancing shelf-life and/or preventing fungal contamination of food-products is also provided.