Abstract: An automatic nucleic acid detection system and a method thereof are disclosed. The automatic nucleic acid detection method includes: performing, by an automatic control subsystem, on a nucleic acid extraction machine platform, a nucleic acid extraction on one or more specimens in a sample tray to generate one or more corresponding nucleic acids in the sample tray; distributing, by the automatic control subsystem, on a nucleic acid distribution machine platform, the nucleic acid in each hole of the sample tray and a first reagent into a plurality of holes of a detection tray, wherein the number of holes of the detection tray is greater than that of the sample tray; and performing, by the automatic control subsystem, on a nucleic acid detection machine platform, a nucleic acid detection on the detection tray.
Abstract: Provided is Lactobacillus paracasei TCI727, deposited in the Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ) with a deposit number of DSM 33756. A method for improving calcium absorption of a subject in need thereof by using the Lactobacillus paracasei TCI727 or metabolites thereof is also provided. The method includes administering to the subject an effective amount of a composition comprising the Lactobacillus paracasei TCI727 or the metabolites thereof.
Abstract: Provided is a method for skin conditioning comprising administering to a subject in need thereof a composition comprising a Dan Feng peony extract, where the Dan Feng peony extract is extracted from flowers of Dan Feng peony. The Dan Feng peony extract is used to increase the production of hyaluronic acid, maintain the structure of skin keratinocytes, and regulate the moisture content of skin cells.
Abstract: A system for increasing the extraction of an active ingredient includes a vacuum quick-dissolving tank, a mixer, a solid-liquid separator, and a homogenizer. The vacuum quick-dissolving tank receives a sample. The mixer is connected to the vacuum quick-dissolving tank, and provides an aqueous solvent to be mixed with the sample. Heating, cooling, stirring, and vacuuming in the vacuum quick-dissolving tank make the sample dissolve and emulsify repeatedly between the vacuum quick-dissolving tank and the mixer to produce a mixture, which is output by the vacuum quick-dissolving tank. The solid-liquid separator receives the mixture output from the vacuum quick-dissolving tank for solid-liquid separation, and outputs an isolated sample liquid. The homogenizer receives the sample liquid output from the solid-liquid separator, performs high-pressure homogenization to obtain an extract liquid containing an active ingredient, and outputs the extract liquid.
Type:
Grant
Filed:
February 8, 2021
Date of Patent:
February 20, 2024
Assignee:
TCI CO., LTD.
Inventors:
Yung-Hsiang Lin, Chien-Yu Lu, Jin-Jia Wang
Abstract: A peptide composition and methods for slimming and/or for promoting the growth of probiotics using early harvested rice prebiotics are provided. The peptide composition or the early harvested rice prebiotics includes at least one peptide as set forth in: SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7 and SEQ, ID NO: 8.
Abstract: Provided is a Lactiplantibacillus plantarum TCI837, deposited in the Leibniz Institute DSMZ under an accession number of DSM 33843. Based on this, the Lactiplantibacillis plantarum TCI837 can be used to prepare a composition for supplementing iron and/or promoting the absorption of iron in a subject, and to prepare a composition for improving the gut microbiota in a subject. In addition, the composition may be an iron supplement composition containing the Lactiplantibacillus plantarum TCI837 and an iron supplement.
Abstract: Prebiotic composition including grape ferment, a first component, and a second component is provided. The first component is lactitol or xylooligosaccharide, and the second component is fructooligosaccharide, xylooligosaccharide, or inulin. The first component is different from the second component, and a weight ratio of the grape ferment, the first component and the second component falls within the range of 1-2:1-2:1-2. Based on this, the prebiotic composition prepared by grape ferment can be used to promote intestinal health of a subject in need thereof and enhance antioxidation in the subject.
Abstract: A method for enhancing skin moisture of a subject in need thereof includes administering to the subject a composition including a white roselle (Hibiscus sabdariffa cv.) extract. The white roselle extract is obtained by lysing a cell wall of a white roselle calyx by ice crystals and extracting the lysed white roselle calyx with a solvent.
Type:
Grant
Filed:
January 28, 2022
Date of Patent:
December 5, 2023
Assignee:
TCI CO., LTD.
Inventors:
Yung-Hsiang Lin, Margaret Lai, Yin-Di Su
Abstract: A method for improving body shape and improving skin condition using a noni fruit ferment is provided, and the method includes: administrating a composition to a subject in need thereof. The composition includes an effective amount of noni fruit ferment. The noni fruit ferment is prepared by (a) mixing glucose and noni fruit with water for extraction, to obtain a noni fruit broth, and (b) fermenting the noni fruit broth with a plurality of bacteria strains. The bacteria strains include yeast, lactic acid bacteria, and acetic acid bacteria. In step (b), the noni fruit broth and the bacteria strains are irradiated with a red light source with a wavelength of 620 nm to 750 nm. In addition, the noni fruit ferment also has at least one of the following functions: removing free radicals, improving defecation status, and improving gastrointestinal motility.
Abstract: The present invention discloses yeast powder rich in nicotinamide mononucleotide, a preparation method and uses thereof. The preparation method includes: preparing a first medium, a second medium, and a third medium; inoculating the first medium with yeast for fermentation to obtain a first fermentation broth; inoculating the second medium with the first fermentation broth for fermentation to obtain a second fermentation broth; inoculating the third medium with the second fermentation broth for fermentation to obtain a third fermentation broth; centrifuging the third fermentation broth to obtain a fermented product; and drying the fermented product to obtain the yeast powder. Components of the first medium, the second medium and the third medium include nicotinamide, tryptophan and niacin. The content of nicotinamide mononucleotide in the yeast powder is at least 5000 ppm.
Abstract: A composition comprising a grape seed extract and a black tea extract. The composition can increase testosterone secretion more effectively than a single component, and can be used for preparing pharmaceutical compositions, foods, health foods, dietary supplements or drinks used for promoting testosterone secretion.
Abstract: The present disclosure provides a method for regulating expression of IL-1? gene, MMP1a gene and TIMP1 gene of chondrocytes using a Lactobacillus plantarum strain TCI227.
Type:
Grant
Filed:
December 7, 2021
Date of Patent:
October 24, 2023
Assignee:
TCI CO., LTD.
Inventors:
Yung-Hsiang Lin, Chu-Han Huang, Cheng-Yu Ho
Abstract: Provided is a plant extract-containing composition for reducing skin damage caused by ultraviolet radiation. The composition includes a combination of extracts of spinach, black tea, green tea, Pu-erh tea, Four Seasons Spring tea, red wine, blueberry, grape seeds, citrus, or green coffee beans.
Abstract: The present disclosure provides peptides comprising a motif having four amino acids, wherein each of the amino acids at N-terminus and C-terminus of the sequence independently has a same or different positively charged side chain, and each of the amino acids between the N-terminal and C-terminal of the motif independently has a same or different uncharged side chain. The present disclosure surprisingly found that these peptides have advantageous effects in inhibiting or decreasing collagen breakdown, increasing production of collagen, elastin and/or hyaluronic acid, retarding aging, improving skin and inhibiting inflammation.
Abstract: A Halobacillus trueperi TCI66207 strain, deposited in the Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures (Accession number DSM 33381). The H. trueperi TCI66207 strain has one or more of the following function: improving skin cell mitochondrion activity, promoting skin cell proliferation, maintaining skin corneum layer completeness, increasing expression of keratin (Keratin14) and/or hyaluronic acid synthase (HAS3) genes and promoting hyaluronic acid production.
Abstract: The present invention provides an Actinidia chinensis Planch ferment and the use thereof in a composition for increasing the antioxidant activity, increasing the anti-glycation activity, increasing the activity of proteolytic enzymes, improving the gastrointestinal dyspepsia, and increasing the gastrointestinal flora diversity. The Actinidia chinensis Planch ferment is prepared by fermenting Actinidia chinensis Planch extract with yeast, lactic acid bacteria and acetic acid bacteria in a three-staged fermentation.
Abstract: The present disclosure provides an extract of early-harvested Citrus reticulata fruit, and a method for reducing lipid accumulation by using the extract of early-harvested Citrus reticulata fruit. The extract of early-harvested Citrus reticulata fruit includes tetramethylisoscutellarein.
Abstract: The present invention relates to a container, a package, a production system, and a distribution system. The container comprises a first identification and a second identification. The first identification is unique for identifying the container and is not exposed. The second identification is unique for identifying the container and is accessible. The second identification is different from the first identification. The second identification is associated with the first identification. The distribution system comprises a processor and a memory. The memory includes instructions causing the processor to perform operations.
Type:
Grant
Filed:
December 2, 2020
Date of Patent:
December 6, 2022
Assignee:
TCI CO., LTD.
Inventors:
Yung-Hsiang Lin, Min Yue, Hsing-I Wang, Tsung Jung Chen
Abstract: A preparation method for a liposome having the ability to stably encapsulate an active ingredient is provided. The preparation method includes providing a mixture and homogenizing the mixture at 300 bar-400 bar to form a liposome suspension. The mixture includes 0.1 wt % of lecithin, 2 wt %-5 wt % of Arabic gum and 63.9125 wt %-97.9 wt % of a solvent. The liposome suspension includes a plurality of liposomes.
Abstract: Provided is a method of promoting the growth of Akkermansia muciniphila, including contacting A. muciniphila with an effective amount of a prebiotic composition including a Musa ferment. Also provided is a prebiotic composition including a Musa ferment. The prebiotic composition promotes the growth of A. muciniphila in the intestine, and reduces the body weight, fat percentage, waist circumference, and hip circumference of obese individuals.
Type:
Grant
Filed:
December 26, 2019
Date of Patent:
October 25, 2022
Assignee:
TCI CO., LTD.
Inventors:
Yung-Hsiang Lin, Chu-Han Huang, Cheng-Yu Ho