Abstract: A suction and removal apparatus which removes highly active pharmacological substances attached to the garments that can re-scatter when changing the clothes and prevents the leakage of such powder to the external environment. The suction and removal apparatus is for sucking and removing in a closed room powder attached to the garments of a person, and includes a suction device, a suction head containing a high efficiency particulate air (HEPA) filter and having a suction port, and a flexible tube connected between the suction device and the suction head. The suction port of the suction head has a cap that closes the suction port, the connection between the suction head and the flexible tube is attachable and detachable, and the suction device is installed outside or inside the room and the suction head and part of the flexible tube are installed inside the room.

Abstract: A sampling vessel which can prevent the operator from being exposed to a powder. A metal sampling vessel (1) for sampling powder has a cylindrical body (2) having a closed first end (2a), an opposite second end (2b) including an opening and a cavity (3), and a connector (6a, 6b) for connecting the cylindrical body (2) to a hanging line. The cylindrical body (2) satisfies a relationship M1>M2, wherein M1 represents the mass between the first end (2a) and a bottom (3c) of the cavity and M2 represents the mass between the opening (5) at the second end and the bottom (3c) of the cavity.

Abstract: A virus inactivation and sampling apparatus for use in a process of purifying a liquid drug substance. A closed circulation line is formed by an outlet port 11 of a bag 10 containing a liquid drug substance, a first line 41, sampling means 20, a second line 42 (pH meter 30) and an inlet port 12 of the bag 10, and an acidic aqueous solution is fed through an acidic aqueous solution line 45 and circulated to inactivate viruses in the liquid drug substance.