Abstract: A system and method for determining the condition of a thermal barrier coating on a base metal component, comprising the use of an induction coil to input into the metallic base layer through the coating layer, a temporally varying heat waveform, and measuring the temperature of the coating surface layer resulting from the input of the heat waveform using a temperature sensor disposed close to the surface of the coating layer. A controller correlates a signal from the temporally varying output of the temperature sensor with a signal corresponding to the temporally varying heat waveform, to determine the phase angle between the signals. The controller uses a mathematical relationship between the phase angle and the frequency of the heat waveform to determine the thermal properties of the non-metallic coating. Both the thermal diffusivity and the barrier coating thickness can be accurately obtained by this method and apparatus.

Abstract: The present invention provides pharmaceutical compositions comprising membrane vesicles, including extracellular vesicles including those referred to as exosomes, loaded with an exogenous Phosphatase and tensin homolog (PTEN) inhibitor. Methods of treating neurological diseases, disorders or conditions using the extracellular vesicles are provided. Isolated extracellular vesicles loaded with an exogenous Phosphatase and tensin homolog (PTEN) inhibitor are provided as well.

Abstract: Provided is an electrode including conductive particles, which sediment under gravitational force and a liquid fluidizing medium flowing through the electrode, in which the conductive particles are suspended and optionally further including conductive particles, which do not sediment under gravitational force when the fluidizing medium flows in the electrode. Further provided are electrochemical devices and energy storage systems including the electrode.

Abstract: A system comprising a protein and a channel. The channel has a domain that binds a membranal component. The channel is configured to carry a liquid sample to an isotachophoresis (ITP) apparatus. The liquid sample comprising or suspected of comprising a cell, a cell membrane or a fraction of a cell membrane. The ITP apparatus comprises a first zone and a second zone. The first zone is configured to contain a solution of high effective mobility leading electrolyte (LE) ion. The second zone is configured to contain a solution of low effective mobility trailing electrolyte (TE) ion. The first zone and the second zone are configured to be operably connected to at least one anode and at least one cathode.

Abstract: A method for sequence-specifically detecting a nucleic acid molecule. The method requires: a) contacting in an absence of an electric field, a mixture of nucleic acid molecules with a base pairing hybridizing molecule (BPHM) having a sequence of interest in a first solution and obtaining a hybrid consisting the nucleic acid molecule and the BPHM; b) introducing the first solution from step (a) into an ITP system, the ITP system comprises a second solution of high effective mobility leading electrolyte (LE) ions and a third solution of low effective mobility trailing electrolyte (TE); and c) applying the electric field across the second solution and the third solution. The hybrid focus at the sharp LE-TE interface in the ITP system. The TE has a higher mobility than the BPHM and the TE has a lower mobility than the hybrid. Sequence-specifically the detecting nucleic acid molecule by a signal from a label.

Abstract: Provided is an electrode including conductive particles, which sediment under gravitational force and a liquid fluidizing medium flowing through the electrode, in which the conductive particles are suspended and optionally further including conductive particles, which do not sediment under gravitational force when the fluidizing medium flows in the electrode. Further provided are electrochemical devices and energy storage systems including the electrode.

Abstract: A system comprising: a handheld mobile device comprising: a projector unit configured to project an image; a camera; and a prism configured to reflect the image projected by the projector such that the camera can capture the projected image.

Abstract: A method that uses at least one hardware processor for receiving a three-dimensional model of an object, receiving an audio sequence embodied as a digital file that comprises a musical composition, generating a video frame sequence, and synthesizing the audio sequence and the video frame sequence into an audiovisual clip. The three-dimensional model is embodied as a digital file that comprises a representation of the object. The generating step comprises computing a caricature of the object by applying a computerized caricaturization algorithm to the three-dimensional model. The computing has scaling gradient fields of surface coordinates of the three-dimensional model by a function of a Gaussian curvature of the surface, and finding a regular surface whose gradient fields fit the scaled gradient fields.

Abstract: The present invention is directed to methods and kits useful for diagnosis and/or prognosis of urothelial cancer in a subject. The present invention further relates to methods of assessing severity of cancer and methods of determining efficacy of a treatment for cancer. The methods and kits of the invention comprise determining the levels of semaphorin 3A in a biological sample of a subject.

Abstract: A multifunctional dielectric gradient metasurface optical device has a layer of nanoscale dielectric gradient metasurface optical antenna elements deposited on a substrate layer, arranged with spatially varying orientations, shapes, or sizes in the plane of the device such that the optical device has a spatially varying optical phase response capable of optical wavefront shaping. The spatially varying optical phase response is a spatial interleaving of multiple distinct phase profiles corresponding to multiple optical sub-elements, thereby providing multifunctional wavefront shaping in the single optical element.

Abstract: The present invention provides a system including: a protein having a domain that binds a membranal component; an inlet for sample flow, an Isotachophoresis (ITP) system and a flow generating means connected or coupled to the aqueous parts of the ITP. The invention also provides a method for detecting and or sorting cells with this system.

Abstract: Computerized, audio-based caricature exaggeration which includes: receiving a three-dimensional model of an object; receiving an audio sequence; generating a video frame sequence, said generating comprising computing a caricature of the object, wherein (a) the computing is with a different exaggeration factor for each of multiple ones of the video frames, and (b) the different exaggeration factor is based on one or more parameters of the audio sequence; and synthesizing the audio sequence and the video frame sequence into an audiovisual clip.

Abstract: The present invention provides a system including: a peptide nucleic acid (PNA) molecule; a DNA molecule, an RNA molecule, or a combination thereof; and an Isotachophoresis (ITP) system. Furthermore, the invention provides a method for sequence-specifically separating and/or identifying a nucleic acid molecule of interest by utilizing the system of the invention to separate and possibly label and/or detect a nucleic acid molecule of interest.

Abstract: A transcutaneous pain reliever which utilizes a plurality of battery powered inductive energy generators, which are sequentially and individually activated, a clocking system which has means for automatically inhibiting pulsing of an energy generator until a previous energy generator has delivered its energy, and an antiadapt system to prevent a patient from becoming acclimated to the sensations. The invention also includes an energy absorption sensor which will indicate the amount of energy not absorbed by the electrodes, a bridged, transformerless battery charger which will permit the use of inexpensive low power diodes and a battery saver which may be used to permit excess energy to charge batteries.