Patents Assigned to Technion Research & Development Foundation Ltd.
  • IMMUNO-MOLECULES CONTAINING VIRAL PROTEINS, COMPOSITIONS THEREOF AND METHODS OF USING
    Publication number: 20120003249
    Abstract: An immuno-molecule which comprises a soluble human MHC class I effector domain; and an antibody targeting domain which is linked to the soluble human MHC class I effector domain, methods of making same and uses thereof.
    Type: Application
    Filed: September 19, 2011
    Publication date: January 5, 2012
    Applicants: Teva Pharmaceutical Industries Ltd., Technion Research & Development Foundation Ltd.
    Inventors: Yoram REITER, Avital Lev
  • LOGIC CIRCUIT AND METHOD OF LOGIC CIRCUIT DESIGN
    Publication number: 20120005639
    Abstract: A complementary logic circuit contains a first logic input, a second logic input, a first dedicated logic terminal, a second dedicated logic terminal, a high-voltage terminal configured for connection to a high constant voltage a low-voltage terminal configured for connection to a low constant voltage, a p-type transistor, and an n-type transistor. The p-type transistor has an outer diffusion connection, a gate connection, an inner diffusion connection, and a bulk connection. The n-type transistor has an outer diffusion connection, a gate connection, an inner diffusion connection, and a bulk connection.
    Type: Application
    Filed: July 7, 2011
    Publication date: January 5, 2012
    Applicant: Technion Research & Development Foundation Ltd.
    Inventors: Alexander Fish, Arkadíy Morgenshtein
  • Integrated system and method for multichannel neuronal recording with spike/LFP separation, integrated A/D conversion and threshold detection
    Patent number: 8090674
    Abstract: A CMOS integrated circuit for multi-channel neuronal recording with twelve true-differential channels, band separation and digital offset calibration. The recorded signal is separated into 2 bands: a low-frequency, local field potential (LFP); and high-frequency spike data. Digitally programmable gains for the LFP and spike bands are provided. A mixed-signal front-end processor for multi-channel neuronal recording is also described. It receives twelve differential-input channels of implanted recording electrodes. A programmable cutoff HPF blocks DC and low frequency input drift at about 1 Hz. The signals are band-split at about 200 Hz to low-frequency local field potential (LFP) and high-frequency spike data (SPK), which is band limited by a programmable-cutoff LPF. The analog signals are converted into digital form, and streamed out over a serial digital bus at up to 8 Mbps.
    Type: Grant
    Filed: July 6, 2005
    Date of Patent: January 3, 2012
    Assignee: Technion Research and Development Foundation, Ltd.
    Inventors: Ran Ginosar, Yevgeny Perelman
  • METHODS AND FORMULATIONS FOR INCREASING INTESTINAL FUNCTION
    Publication number: 20110306544
    Abstract: A method for increasing intestinal function is provided. The method comprising orally and/or enterally administering to a subject in need thereof a therapeutically effective amount of insulin, thereby increasing intestinal function.
    Type: Application
    Filed: August 19, 2011
    Publication date: December 15, 2011
    Applicant: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD.
    Inventors: Igor Sukhotnik, Naim Shehadeh, Raanan Shamir
  • EFFICIENT SAMPLING AND RECONSTRUCTION OF SPARSE MULTI-BAND SIGNALS
    Publication number: 20110294453
    Abstract: A method for signal processing includes distributing an analog input signal to a plurality of processing channels. In each processing channel, the input signal is mixed with a respective periodic waveform including multiple spectral lines, so as to produce a respective baseband signal in which multiple spectral slices of the input signal are superimposed on one another. The baseband signal produced in each of the processing channels is digitized, to produce a set of digital sample sequences that represent the input signal.
    Type: Application
    Filed: February 15, 2010
    Publication date: December 1, 2011
    Applicant: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD.
    Inventors: Moshe Mishali, Yonina Eldar
  • Antigen-presenting complex-binding compositions and uses thereof
    Publication number: 20110293616
    Abstract: A composition-of-matter comprising an antibody or antibody fragment including an antigen-binding region capable of specifically binding an antigen-presenting portion of a complex composed of a human antigen-presenting molecule and an antigen derived from a pathogen is disclosed.
    Type: Application
    Filed: November 19, 2009
    Publication date: December 1, 2011
    Applicant: Technion Research & Development Foundation Ltd.
    Inventors: Yoram Reiter, Cyril Cohen
  • Probe and system for electron spin resonance imaging
    Patent number: 8067937
    Abstract: ESR imaging probe, system, and method are described. The probe is an ex-situ probe, the system comprises the probe and configured for operating the probe, and the method comprises detecting ESR from outside a resonator of the probe. An exemplary embodiment of a probe according to the invention comprises a cooled dielectric resonator, and one sided gradient coils. An exemplary embodiment of the system comprises source current that is configured to supply to the gradient coils currents of up to 100 A in pulses shorter than 1 ?sec.
    Type: Grant
    Filed: June 14, 2007
    Date of Patent: November 29, 2011
    Assignee: Technion Research & Development Foundation Ltd.
    Inventors: Aharon Blank, Lazar Shtirberg
  • METHODS AND SYSTEMS FOR MANAGING A MULTI PARTICIPANT EVENT
    Publication number: 20110289149
    Abstract: A method for managing communication among a plurality of social network members. The method comprises defining a multi participant task, setting at least one forward rule limiting the distribution an invitation message for participating in the multi participant task, forwarding the invitation message to at least one addressee from a plurality of social network members, allowing the at least one addressee to forward the invitation message to at least one additional addressee from the plurality of social network members under the at least one forward rule, monitoring a plurality of feedbacks to the invitation message to determine whether the multi participant task is achieved, and updating a status of the multi participant task according to the determination.
    Type: Application
    Filed: May 19, 2011
    Publication date: November 24, 2011
    Applicant: Technion Research & Development Foundation Ltd.
    Inventors: Oded SHMUELI, Royi Ronen
  • Volatile Organic Compounds as Diagnostic Markers in the Breath for Lung Cancer
    Publication number: 20110277538
    Abstract: A set of volatile organic compounds is provided, comprising at least butylated hydroxy toluene or 4,6-di(1,1-dimethylethyl)-2-methyl-phenol for breath analysis. Methods of use thereof in diagnosing, monitoring or prognosing lung cancer are also disclosed.
    Type: Application
    Filed: January 10, 2010
    Publication date: November 17, 2011
    Applicant: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
    Inventor: Hossam Haick
  • Neuroprotective iron chelators and pharmaceutical compositions comprising them
    Patent number: 8058442
    Abstract: Novel iron chelators exhibiting neuroprotective and good transport properties are useful in iron chelation therapy for treatment of a disease, disorder or condition associated with iron overload and oxidative stress, eg. a neurodegenerative or cerebrovascular disease or disorder, a neoplastic disease, hemochromatosis, thalassemia, a cardiovascular disease, diabetes, a inflammatory disorder, anthracycline cardiotoxicity, a viral infection, a protozoal infection, a yeast infection, retarding ageing, and prevention and/or treatment of skin ageing and skin protection against sunlight and/or UV light. The iron chelator function is provided by a 8-hydroxyquinoline, a hydroxypyridinone or a hydroxamate moiety, the neuroprotective function is imparted to the compound e.g. by a neuroprotective peptide, and a combined antiapoptotic and neuroprotective function by a propargyl group.
    Type: Grant
    Filed: November 7, 2003
    Date of Patent: November 15, 2011
    Assignees: Technion Research and Development Foundation Ltd., Yeda Research and Development Co., Ltd.
    Inventors: Moussa Youdim, Matitiyahu Fridkin, Hailin Zheng, Abraham Warshawsky, Rivka Warshawsky, legal representative
  • Oscillating mirror having a plurality of eigenmodes
    Patent number: 8054522
    Abstract: Geometric-waveform oscillator for processing light, the geometric waveform oscillator including a plurality of masses, at least one force producing element, and a plurality of elastic elements, each of the force producing elements being coupled with a respective one of the masses, at least one of the masses including a light processing module, each of the force producing elements applying a force to the masses, the elastic elements coupling the masses together, the elastic elements coupling the masses with a respective support, wherein the mass values of the masses, the force values of the forces, and the stiffness coefficients of the elastic elements, are selected such that the light processing module oscillates according to the geometric-waveform.
    Type: Grant
    Filed: April 20, 2004
    Date of Patent: November 8, 2011
    Assignee: Technion Research & Development Foundation Ltd.
    Inventors: Mordekhai Velger, Izhak Bucher, Yaron Zimmerman
  • Detection of Cancer through Breath Comprising a Sensor Array Comprising Capped Conductive Nanoparticles
    Publication number: 20110269632
    Abstract: Sensor array for detecting biomarkers for cancer in breath samples. The sensor array is based on 2D films or 3D assemblies of conductive nanoparticles capped with an organic coating wherein the nanoparticles are characterized by a narrow size distribution. Methods of use of the sensor array for discriminating between patterns of volatile organic compounds from healthy individuals and patients with various types of cancer are disclosed.
    Type: Application
    Filed: January 10, 2010
    Publication date: November 3, 2011
    Applicant: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
    Inventors: Hossam Haick, Peng Gang, Orna Adams
  • APPARATUS AND METHOD FOR FINDING VISIBLE POINTS IN A CLOUD POINT
    Publication number: 20110267345
    Abstract: The subject matter discloses a method of determining whether a point in a computerized image is visible from a viewpoint; said image is represented as a point cloud, the method comprising: performing inversion on a the vicinity of the point thus creating a computerized inversed objects each point in the vicinity of the point is related to a parallel point in the computerized inversed object and obtaining a convex hull of the inversed object; the point is likely to be visible from the viewpoint in case it belongs to the point set composing the convex hull.
    Type: Application
    Filed: May 24, 2009
    Publication date: November 3, 2011
    Applicant: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD
    Inventors: Sagi KATZ, Ayellet Tal
  • Apparatus and method for excitation of a single mode in a waveguide
    Patent number: 8045830
    Abstract: A wave-guiding system and method for mode-selective transmission of a spatially coherent light beam is disclosed. The system comprises a wave-guide with an inlet and an outlet for transmitting one or more modes; a first mode-shaping optical element for shaping the spatially coherent light beam before it enters through the inlet of the wave-guide to a desired mode of the wave-guide; and a second mode-shaping optical element for shaping light beam after it exits from the outlet of the wave-guide for obtaining a desired vectorial field.
    Type: Grant
    Filed: August 28, 2007
    Date of Patent: October 25, 2011
    Assignee: Technion Research and Development Foundation Ltd.
    Inventor: Erez Hasman
  • LIGHT EMITTING SYSTEM AND METHOD OF FABRICATING AND USING THE SAME
    Publication number: 20110254471
    Abstract: A light emitting system is disclosed. The system comprises an active region having a stack of bilayer quantum well structures separated from each other by barrier layers. Each bilayer quantum well structure is formed of a first layer made of a first semiconductor alloy for electron confinement and a second layer made of a second semiconductor alloy for hole confinement, wherein a thickness and composition of each layer is such that a characteristic hole confinement energy of the bilayer quantum well structure is at least 200 meV.
    Type: Application
    Filed: February 21, 2011
    Publication date: October 20, 2011
    Applicant: Technion Research & Development Foundation Ltd.
    Inventors: Gad BAHIR, Dan Fekete, Asaf Albo
  • APPARATUS AND METHODS FOR DIAGNOSING RENAL DISORDERS
    Publication number: 20110244584
    Abstract: The present invention provides a system comprising an array of chemically sensitive sensors based on coated single walled carbon nanotubes, for measuring volatile organic compounds indicative of renal failure. Methods of breath analysis for diagnosing chronic, acute and end-stage renal failure are disclosed.
    Type: Application
    Filed: December 2, 2009
    Publication date: October 6, 2011
    Applicant: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
    Inventors: Hossam Haick, Zaid Abassi, Farid Nakhoul
  • Spray method for producing semiconductor nano-particles
    Patent number: 8030194
    Abstract: A method is provided for producing semiconductor nanoparticles comprising: (i) dissolving a semiconductor compound or mixture of semiconductor compounds in a solution; (ii) generating spray droplets of the resulting solution of semiconductor compound(s); (iii) vaporizing the solvent of said spray droplets, consequently producing a stream of unsupported semiconductor nanoparticles; and (iv) collecting said unsupported semiconductor nanoparticles on a support.
    Type: Grant
    Filed: September 22, 2005
    Date of Patent: October 4, 2011
    Assignee: Technion Research and Development Foundation Ltd.
    Inventors: Lilac Amirav, Efrat Lifshitz
  • Spectrum-blind sampling and reconstruction of multi-band signals
    Patent number: 8032085
    Abstract: A signal processing method includes sampling an analog signal, which has a spectral density defining one or more bands, to produce a digitized signal. A spectral transform of the digitized signal is expressed as a matrix multiplied by a vector, wherein the vector includes multiple elements that represent the spectral density of the analog signal as a function of frequency within respective spectral slices. Indices of a subset of the elements of the vector, in which the spectral density is concentrated, is determined. The analog signal is reconstructed from the digitized signal using the subset of the elements of the vector and a corresponding subset of columns of the matrix having the indices.
    Type: Grant
    Filed: January 23, 2008
    Date of Patent: October 4, 2011
    Assignee: Technion Research & Development Foundation Ltd.
    Inventors: Moshe Mishali, Eldar Yonina
  • POLYMER-CONJUGATED ALBUMIN HYDROGELS FOR CONTROLLED RELEASE OF THERAPEUTIC AGENTS
    Publication number: 20110238000
    Abstract: A hydrogel system comprising polymer-conjugated albumin molecules is provided for controlled release delivery of therapeutic agents. The polymer is a functionalized synthetic polymer, preferably PEG-diacrylate. The polymer-conjugated albumin is preferably mono-PEGylated albumin. The hydrogel system may comprise a matrix to which the polymer-conjugated albumin molecules are linked via a functional group of the polymer. The matrix may be formed from the same polymer of the polymer-albumin conjugate.
    Type: Application
    Filed: December 7, 2009
    Publication date: September 29, 2011
    Applicant: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
    Inventors: Dror Seliktar, Liat Oss-Ronen
  • Methods and formulations for increasing intestinal function
    Patent number: 8026211
    Abstract: A method for increasing intestinal function is provided. The method comprising orally and/or enterally administering to a subject in need thereof a therapeutically effective amount of insulin, thereby increasing intestinal function.
    Type: Grant
    Filed: June 2, 2005
    Date of Patent: September 27, 2011
    Assignee: Technion Research & Development Foundation Ltd.
    Inventors: Igor Sukhotnik, Naim Shehadeh, Raanan Shamir