Abstract: A microreactor includes an outer member with a tapered inner peripheral surface, an inner member with a tapered outer peripheral surface, a clearance adjusting unit which enables adjustment of clearance distance L between the tapered inner peripheral surface and the tapered outer peripheral surface by relatively moving the outer member and the inner member in vertical direction.

Abstract: A disperser includes an outer member and an inner member located radially inside the outer member. A flow path is formed between the outer member and the inner member, through which fluid flows from one side to the other side in the axial direction. The flow path includes a first region that extends spirally from the one side to the other side and a second region that extends continuously from the first region to the other side. The second region is defined by the tapered inner circumferential surface of the outer member and the tapered outer circumferential surface of the inner member. The tapered inner circumferential surface and the tapered outer circumferential surface are formed such that the angle of one with respect to the other in the axial cross section changes in the middle of the second region, and the second region of the flow path has portions each having a different clearance distance.

Abstract: A disperser includes an outer member having a tapered inner circumferential surface, an inner member having a tapered outer circumferential surface that faces the tapered inner circumferential surface, and a clearance adjustment part that allows a clearance distance between the tapered inner circumferential surface and the tapered outer circumferential surface to be adjusted by moving the outer member and the inner member relative to each other. A flow path is formed between the inner circumferential surface of the outer member and the outer circumferential surface of the inner member, through which fluid flows from one side to the other side. The flow path includes a dispersion region defined by the tapered inner circumferential surface and the tapered outer circumferential surface. The tapered inner circumferential surface and the tapered outer circumferential surface are formed such that the angle of one with respect to the other in the axial cross section changes in the middle of the dispersion region.

Abstract: A heat exchanger with which a fluid to be treated or a generated gas can be prevented from stagnating in a heat transfer part, which can be disassembled for good washability, and which can be coated or lined. The heat exchanger is provided with tow flow passages, i.e. a first flow passage and a second flow passage, within a space formed between an inner tube and an outer tube which are concentric to each other. A spiral heat transfer body is disposed between the inner tube and the outer tube, and the spiral heat transfer body has a cross-sectional shape that is substantially triangular in the axial-direction cross section. The space is partitioned into the first flow passage and the second flow passage by the spiral heat transfer body, and heat is exchanged via the spiral heat transfer body between a first fluid flowing within the first flow passage and a fluid flowing within the second flow passage.

Abstract: A heat exchanger includes three flow paths, a first flow path, a second flow path, and a third flow path, which turn spirally in the space formed between an inner cylinder and an outer cylinder are provided. These flow paths are defined by an inner heat transfer body and an outer heat transfer body, and heat exchange is performed through the heat transfer bodies. The heat transfer bodies turn spirally, have a screw shape in an axial cross-sectional view, and are assembled into a screw shape. The flow path area of the first flow path is varied by changing the shapes of a male thread and a female thread, and the second flow path and the third flow path are formed in a spiral shape, allowing for exchange of heat through the heat transfer bodies.

Abstract: The present application provides a microsphere comprising a lactic acid-glycolic acid copolymer (PLGA) or polylactide (PLA) as a main component, in which a biologically active substance is uniformly dispersed, wherein an average volume-based particle diameter of the microsphere is 1 ?m or more and 150 ?m or less, and a variation coefficient of area ratios in six regions is 0.35 or less, wherein the area ratios in six regions are calculated by (s/A)×100 (%) wherein the six regions are prepared by preparing a cross section observation sample obtained by cutting the microsphere; observing the cross section observation sample with an electron microscope at a magnification capable of confirming the biologically active substance in the microsphere or a higher magnification; and dividing the electron microscope observation image into six regions; and A is an area of a respective divided region, and s is a sum of cross section areas of the biologically active substance included in the respective divided region.

Abstract: A vacuum deaerator degasses material to be processed by placing a rotating rotor with a screen in a vacuum vessel, introducing a liquid material to be processed into the rotor from the interior thereof and causing the liquid to pass through the screen to refine the same. The vacuum deaerator is characterized in that: the screen is a cylinder with a circular cross-section and is in the form of a porous plate in which a plurality of through holes are opened in the radial direction of the cylindrical screen; and the screen is provided such that the area of inflow openings is greater than the area of outflow openings, where the inflow openings are openings of a plurality of penetration portions provided on the inner wall face of the screen and the outflow openings are openings of the plurality of penetration portions provided on the outer wall dace of the screen. Thus, the processing capacity of the vacuum deaerator is improved without increasing the size of the device.

Abstract: The present invention is a method of producing highly crystalline silver microparticles by a reduction reaction, which comprises precipitating the silver microparticles by reacting a silver solution containing at least silver ions and a reducing agent solution containing at least a reducing agent by a continuous wet reduction method, wherein a reduction rate from the silver solution to the silver microparticles is 99% or more; an average primary particle diameter of the silver microparticles is 100 nm or more and 1,000 nm or less; and an average crystallite diameter relative to the average primary particle diameter of the silver microparticles is 80% or more. Even highly crystalline silver microparticles having 95% or more of the ratio (d/D) of the average crystallite diameter (d) relative to the average primary particle diameter (D), that is, silver microparticles in which almost all silver microparticles are single crystals, can be continuously produced by a liquid phase method, by the present invention.

Abstract: A fluid treatment device with a new configuration is provided. The fluid treatment device is provided with an upstream treatment unit defined by treatment surfaces that rotate relative to each other, and a downstream treatment unit arranged downstream of the upstream treatment unit. The upstream treatment unit is configured such that, by passing the fluid to be treated into an upstream treatment space defined by the treatment surfaces, the fluid to be treated is subjected to upstream treatment. The downstream treatment unit is provided with a downstream treatment space which performs the function of retaining and mixing the fluid to be treated by means of a labyrinth seal. An upstream outlet of the fluid to be treated from the upstream treatment unit opens into the downstream treatment space, and the downstream treatment space is configured to use the labyrinth seal to perform the function of controlling retention time.

Abstract: A vacuum deaerator is provided with a refining device with which it is possible to suppress the occurrence of situations involving interrupted discharging and continuously discharge a material being treated that is highly viscous, etc. The vacuum deaerator introduces a liquid material being treated into a vessel having a vacuum therein to perform deaeration and then discharged the material being treated out of the vessel. A rotating rotor with refining device arranged in the vessel and a rotating discharge vane provided separately from the rotating rotor for the purpose of discharging the material being treated in the vessel out of the vessel are installed.

Abstract: The flow reactor includes three flow passages including a first flow passage, a second flow passage, and a third flow passage which spirally circulate within a space formed between an inner tube and an outer tube. The flow passages are compartmented by an inner heat transfer body and an outer heat transfer body. The heat transfer bodies spirally circulate, have a screw-like cross-sectional shape in an axial cross-sectional view, and are assembled in a screw-like configuration. By changing the shapes of a male-thread portion and a female-thread portion, the flow passage area of the first flow passage is changed, the second flow passage and the third flow passage are spirally formed, and heat exchange and reaction take place through the heat transfer bodies.

Abstract: The present invention relates to silicon compound coated metal magnesium particles in which at least a part of a surface of the metal magnesium particles is coated with the silicon compound, wherein an average particle diameter of the silicon compound coated metal magnesium particles is 5 nm or more and 500 nm or less, and a thickness of the silicon compound coating is 1 nm or more and 50 nm or less. The silicon compound coated metal magnesium particles of the present invention are easy to handle in the atmosphere, and have excellent oxidation resistance, and further the properties expected of the nano-size metal magnesium particles are improved at a maximum, or the properties are controlled by supplementing the properties.

Abstract: The present application provides black perylene pigment microparticles having an average circularity of 0.8 or more which are amorphous; and a method of producing the black perylene pigment microparticles, which comprises a step of mixing a pigment solution in which a black perylene pigment is dissolved and a precipitation solvent for precipitating black perylene pigment microparticles from the pigment solution to form black perylene pigment microparticles, wherein at least one of the pigment solution and the precipitation solvent independently includes a salt of an alkaline earth metal and/or a particle growth inhibitor. The present invention can provide black perylene pigment microparticles having good dispersibility, high concealability and light-shielding property and controlled hue and chroma, and a method of easily producing the same, and the like.

Abstract: In a coloring ultraviolet protective agent, the average molar absorption coefficient in the wavelength range from 200 nm to 380 nm is increased, and the color characteristics in the visible region are controlled. The coloring ultraviolet protective agent is useful for shielding ultraviolet rays and coloring.

Abstract: The present application provides a microsphere comprising a lactic acid-glycolic acid copolymer (PLGA) as a main component, in which a biologically active substance is uniformly dispersed, wherein an average volume-based particle diameter of the microsphere is 1 ?m or more and 150 ?m or less, and a mass of the biologically active substance or an empty hole of 1.5 ?m or more is not present in the microsphere. The microsphere of the present invention can appropriately control the initial release amount of the biologically active substance and its release rate during a subsequent release period, and can continuously release the biologically active substance in vivo for a predetermined period of time.

Abstract: A heat exchanger includes a structure that is advantageous in increasing the overall heat transfer coefficient which represents the efficiency of heat exchange. Three flow paths, a first flow path, a second flow path, and a third flow path, which turn spirally in the space formed between an inner cylinder and an outer cylinder are provided. These flow paths are defined by an inner heat transfer body and an outer heat transfer body, and heat exchange is performed through the heat transfer bodies. The heat transfer bodies turn spirally, have a screw shape in an axial cross-sectional view, and are assembled into a screw shape. The flow path area of the first flow path is varied by changing the shapes of a male thread and a female thread, and the second flow path and the third flow path are formed in a spiral shape, allowing for exchange of heat through the heat transfer bodies.

Abstract: Provided are a method for producing organic material microparticles and a method for modifying organic material microparticles, whereby it becomes possible to improve the crystallinity of organic material microparticles or achieve the crystal transformation of the organic material microparticles while preventing the growth of the organic material microparticles in a solvent. A surfactant is added to a solvent that is capable of partially dissolving organic material microparticles, and then the organic material microparticles are reacted with the solvent. In this manner, it becomes possible to improve the degree of crystallization of the organic material microparticles or achieve the crystal transformation of the organic material microparticles without substantially altering the particle diameters of the organic material microparticles.

Abstract: The present application provides a microsphere in which a main agent is uniformly dispersed in a polymer matrix, wherein an average volume-based particle diameter of the microsphere is 1 ?m or more and 150 ?m or less, and a variation coefficient of area ratios in four regions is 0.35 or less, wherein the area ratios in four regions are calculated by (s/A)×100 (%) wherein the four regions are prepared by preparing a cross section observation sample obtained by cutting the microsphere; observing the cross section observation sample with an electron microscope at a magnification capable of confirming the main agent in the microsphere or a higher magnification; and dividing the electron microscope observation image into four regions; and A is an area of a respective divided region, and s is a sum of cross section areas of the main agent included in the respective divided region.

Abstract: Provided are a method for producing organic material microparticles and a method for modifying organic material microparticles, whereby it becomes possible to improve the crystallinity of organic material microparticles or achieve the crystal transformation of the organic material microparticles while preventing the growth of the organic material microparticles in a solvent. A surfactant is added to a solvent that is capable of partially dissolving organic material microparticles, and then the organic material microparticles are reacted with the solvent. In this manner, it becomes possible to improve the degree of crystallization of the organic material microparticles or achieve the crystal transformation of the organic material microparticles without substantially altering the particle diameters of the organic material microparticles.

Abstract: A stirrer is provided that can more efficiently achieve shearing applied, by an action of an intermittent jet flow, to a fluid to be processed.