Abstract: The present invention provides a method and apparatus for depth image acquisition of an object wherein at least two time-of-flight cameras are provided and the object is illuminated with a plurality of different light emission states by emitting light signals from each camera. Measurements of the light reflected by the object during each light emission state are obtained at all the cameras wherein the measurements may then be used to optimise the depth images at each of the cameras.

Abstract: The present invention is directed to a method for preparing an expression vector encoding a tailored recombinase, wherein said tailored recombinase recombines asymmetric target sites within the LTR of proviral DNA of a retrovirus inserted into the genome of a host cell and is useful as means for excising the provirus from the genome of the host cell. The present invention further relates to an in vitro-method of optimising the treatment of a retroviral infection of a subject and to the use of tailored recombinases for the preparation of pharmaceutical compositions for reducing the viral load in a subjected infected by a retrovirus.

Abstract: The invention relates to a method of producing solid oxide fuel cells (SOFC) having a cathode-electrolyte-anode unit supported by a metal substrate. It is the object of the invention in this respect to provide solid oxide fuel cells which achieve an increased strength, improved temperature change resistance, a secure bonding of films forming the cathode-electrolyte-anode unit and can be produced free of distortion and reproducibly. In the method in accordance with the invention, a film forming the anode is first wet chemically applied to a surface of a porous metallic substrate as a carrier of the cathode-electrolyte-anode unit. An element which has already been sintered gas tight in advance and which forms the electrolyte is then placed on or applied a really to this film forming the anode and at a first thermal treatment up to a maximum temperature of 1250° C.

Abstract: A method is provided for producing a microstructured molded object that is intended for culturing of biological cells. According to this method, a plastically deformable first porous film is prepared, as well as a deformable second film and a deformable sacrificial film. The first, second and sacrificial film are placed in a stack. Next, the sacrificial film is subjected to pressure to press the stack into a mold. The mold has recesses, such that deformed regions in the form of cavities are produced in the sacrificial film, the first film and the second film, and undeformed regions remain. During the pressing of the film stack into the mold, the first film and the second film are joined to each other, so that they form a composite film. At least portions of the deformed regions of the second film are etched so that sections of the second film are chemically dissolved.

Abstract: An embodiment of the invention relates to a single photon emission system having a proximal end, a distal end, and a single photon emitter located between the proximal end and the distal end; wherein the single photon emission system is adapted to guide optical pump radiation, which is inputted at the proximal end to optically excite the single photon emitter, along a predefined direction that runs from the proximal end to the distal end; and wherein single photons emitted by said single photon emitter, are guided along said predefined direction to the distal end.

Abstract: The present invention relates to a method for producing hair microfollicles comprising the steps of: a) providing de novopapillae, b) providing other cell populations selected from the group of fibroblasts, keratinocytes and melanocytes, and co-culturing the de novopapillae with at least one other cell population in non-adherent culture vessels. The present invention relates also to methods of producing de novo papillae usable in said method for producing hair microfollicles.

Abstract: The present invention relates to peptide-mimetic compounds, the synthesis and use thereof fort he inhibition of proteasomes and the induction of apoptosis in tumor cells. The present invention furthermore relates to pharmaceutical compositions comprising the compounds and the use of the compounds for a treatment of diseases, in particular cancer and neurodegenerative diseases.

Abstract: An arrangement of floating platforms is provided, including (a) an anchored main platform and (b) one or more outer platforms, each of which being connected to the main platform by at least one connection element. One or more of the main and/or outer platforms are rotatable about a vertical axis by drive units which are fixed thereon. Marine engines having a propeller propulsion system are provided as drive units on the main platform and/or the outer platforms.

Abstract: The invention relates to a method of estimating BEM coefficients of the Channel taps of a transmission Channel of an OFDM System having a given pilot arrangement, comprising, at the receiver side of the transmission Channel, the Steps of a) subsampling a received OFDM symbol in the frequency domain into a set of subsequences, b) inverse Fourier transforming each subsequence into a transformed subsequence, and c) estimating Fourier coefficients of a truncated Fourier series expansion model of the Channel taps from the set of transformed subsequences.

Abstract: A method and a device for processing a light-polymerizable material (5, 55) for building up an object (27) in layers, using a lithography based generative manufacture having a construction platform (12) for building up the object (27), a projecting exposure unit (10, 60) that can be controlled for locally selected exposing of a surface on the construction platform (12, 62) to an intensity pattern having a prescribed shape, and a control unit (11, 61) prepared for polymerizing overlapping layers (28) on the construction platform (12, 62) in successive exposure steps, each having a prescribed geometry, by controlling the projecting exposure unit (10, 60), in order to thus successively build up the object (27) in the desired shape, said shape resulting from the sequence of layer geometries.

Abstract: The present invention relates to a novel polymeric material with enhanced hydrophilicity for medical use comprising a biocompatible polyester material selected from the group consisting of poly(hydroxyalkanoate)s, poly(lactic acid)s, poly(glycolic acid)s, poly(caprolactone)s and copolymers and blends thereof, wherein the biocompatible polyester material is crosslinked with a functionalized poly(alkylene oxide) having at least two functional groups independently selected from the group consisting of azido-formate and alkanoyl azide. The novel polymeric material with enhanced hydrophilicity is useful as a biocompatible material in a variety of medical applications, including medical implants, bioresorbable implants, tissue engineering, and controlled release.

Abstract: The present invention relates to pre-catalysts for olefin metathesis and composition involving these pre-catalysts.

Abstract: A compound of formula (I) as defined herein is useful in the treatment and prevention of a disorder such as cachexia, stroke, atherosclerosis, coronary artery disease, and diabetes and pharmaceutical compositions of the same. Also, a method of screening for lipase inhibitors using a compound of formula (I) and determining its lipase inhibitory activity. The method includes in vitro assays of compounds using ATGL and/or HSL, and cellular assays wherein inhibition is followed by observing indicators of efficacy. Also, methods for treatment or prevention of a condition involving cachexia, stroke, artherosclerosis, coronary artery disease, diabetes, preferably diabetes type II by administering a pharmaceutical composition comprising an agent which is able to inhibit ATGL. Also contemplated herein, are compositions comprising one or more ATGL-inhibiting agents optionally in combination with one or more lipase inhibitors or inhibitors of inflammatory cytokines.

Abstract: The invention relates to a valve for controlling a flow of a fluid through a fluid channel, comprising a tube of flexible material in which a section of a fluid channel is formed, a valve component assigned to the tube, a squeeze element, which is formed and configured on the valve component by pressing against an outside surface of the tube to control a flow of a fluid through the fluid channel, optionally up to the closing of the fluid channel, a guide section, which is formed on the valve component, and a guide assigned to the valve component, which cooperates with the guide section in a relative movement of the guide and valve components relative to one another in the longitudinal direction of the tube, such that the squeeze element is displaced in the relative movement, changing the pressure on the outside surface of the tube and thus changing the flow through the fluid channel.

Abstract: A sensor system is located in an environment composed of a first medium, where waves propagate with a first phase velocity, the sensor system including at least one main enclosure and a sensor array with at least two sensors, said sensor array being arranged inside the main enclosure, wherein the space inside the main enclosure between the sensor array and the inner surface of the main enclosure is filled with a second medium, in which waves propagate with a second phase velocity, the second phase velocity being different from the first velocity.

Abstract: In a method for producing a whey protein hydrolysate, a whey substrate, selected from the group consisting of whey, commercially available whey powder, whey protein isolate, whey protein preparations, and ?-Lactalbumin obtained from whey, is enzymatically hydrolyzing at least with alcalase and trypsin as enzymes at a ratio of g enzymes/g whey substrate between 1:10 and 1:10,000 and at a temperature of between 30° C. and 70° C. within an incubation period of between 18 hours and 30 hours, until a hydrolysis degree of more than 50% of the protein of the whey substrate have a molecular weight of less than 4 kDa. The enzymes are inactivated by heating the enzymes to a temperature of 80° C. to 100° C. after the desired hydrolysis degree has been reached.

Abstract: What is described is an actuator system (2) comprising at least one actuator (29, 29?) and an associated control system (8) which is designed for at least two operating modes, at least one of which may be deactivated, whereby one of the operating modes is a high efficiency operating mode.

Abstract: A method of equalizing a signal received over transmission channel defined by BEM coefficients of a basis expansion model of its channel taps, comprising the step of approximately solving the relation (I) for x[n] by an iterative method, n being the index of time, y[n] being the received signal, x[n] being the equalized signal, Bm[n] being the mth basis function of the basis expansion model, M being the model order of the basis expansion model, and blm being the BEM coefficient of the mth of the basis function of the lth channel tap, and w[n] being optional noise.

Abstract: An embodiment of the invention relates to a method for providing a compressed video bitstream related to consecutive pictures of a video sequence, wherein the pictures are defined by pixels, said method comprising the steps of: (a) applying at least one higher-order motion model to a motion vector field and generating at least one higher-order motion parameter set for said motion vector field, wherein said motion vector field comprises a plurality of first motion vectors, each first motion vector being assigned to a pixel block and describing the local displacement of the pixel block from the preceding picture to the consecutive picture, and wherein each pixel block comprises a plurality of pixels; (b) calculating a second motion vector for each pixel block based on the higher-order motion parameter set; (c) calculating the deviation between the first motion vector and the second motion vector for each pixel block; and (d) generating a video bitstream comprising the higher-order motion parameter set, and f

Abstract: The present invention relates to an optical coherence tomography system having an interferometer, in particular a Michelson interferometer, having a reference arm for variable adjustment of an optical reference path length and having a measuring arm in which an object to be scanned can be disposed and/or is disposed in a sample volume, wherein a focusing system which is configured for focusing divergently incident light beams on a common point situated in the sample volume is disposed in the measuring arm between the beam splitter of the interferometer and the sample volume.