Abstract: A semiconductor device for emitting electromagnetic radiation, and to a method of producing the same, which can be used as a semiconductor-based, structured light source. The semiconductor device comprises a layer stack structure composed of an n-doped layer, an active layer and a p-doped layer, as well as a connection structure comprising conductor layers and at least one insulator layer, the conductor layers being arranged, parallel to and spaced apart from one another, along a first direction that is parallel to the active layer of the layer stack structure, and at least one insulator layer being arranged between at least two conductor layers, one or more conductor layers being electrically connected to the p-doped layer of the layer stack structure.

Abstract: The present invention relates to human tissue kallikrein 7 (KLK7) selective inhibitor compounds, combinations including these compounds, process to obtain the referred compounds, and methods of using the same. The present invention belongs to the field of chemistry, pharmacology and medicine.

Abstract: The present disclosure provides methods and composition including vaccines, monoclonal antibodies, polyclonal antibodies, chimeric molecule of an extracellular fibrinogen binding protein (Efb) and targeted agent delivery pharmaceutical composition comprising at least a portion of a modified N-terminus region, at least a portion of a modified C-terminus region, or both, wherein the modified extracellular fibrinogen binding protein results in inhibiting the fibrinogen binding, C3 binding, or both or administering to a subject a pharmacologically effective amount of a vaccine in a pharmaceutically acceptable excipient, comprising a modified extracellular fibrinogen binding protein comprising at least a portion of a modified N-terminus region, at least a portion of a modified C-terminus region, or both, wherein the modified extracellular fibrinogen binding protein results in not shielding the staphylococcus bacterium from recognition by a phagocytic receptor.

Abstract: A semiconductor device for emitting electromagnetic radiation, and to a method of producing the same, which can be used as a semiconductor-based, structured light source. The semiconductor device comprises a layer stack structure composed of an n-doped layer, an active layer and a p-doped layer, as well as a connection structure comprising conductor layers and at least one insulator layer, the conductor layers being arranged, parallel to and spaced apart from one another, along a first direction that is parallel to the active layer of the layer stack structure, and at least one insulator layer being arranged between at least two conductor layers, one or more conductor layers being electrically connected to the p-doped layer of the layer stack structure.

Abstract: The invention provides a fusion protein for use in the treatment of HvG disease in a patient having received a transplant, for use in suppressing the host's immune response directed against the transplant. The fusion protein is adapted for use in suppressing the immune rejection of a transplant which contains or expresses HLA-A*02 or SLA-01*0401 in a recipient patient who is negative for HLA-A*02 or SLA-01*0401, i.e. the patient prior to transplantation does not express HLA-A*02 or SLA-01*0401. The fusion protein is a chimeric antigen receptor (CAR), which upon expression in regulatory T-cells (Treg) causes a specific suppressor activity of the regulatory T-cells in the presence of HLA-A*02 or SLA-01*0401.

Abstract: The present invention relates to combinations of tick-derived antigens for use as a tick vaccine.

Abstract: Positioning structures in at least one indentation present on a or in a support, wherein said indentation is an indentation having a diameter in the nanometer range, makes it possible to position the structure in the indentation substantially centrally with defined orientation. A support having at least one indentation, wherein the indentation has a size in the nanometer range, includes a predetermined structure which is arranged substantially centrally within said indentation and which optionally has a functional unit diametrically opposite to the side pointing to the bottom surface. The arrangement is especially suitable for single molecule analysis and, here especially, for single molecule sequencing and other high-throughput methods.

Abstract: The invention relates to a power circuit breaker that is suitable for switching electrical voltages. The power circuit breaker according to the invention comprises two main electrodes, to each of which a respective pole of the voltage to be switched can be connected. During the switching process, at least one of said main electrodes follows a switching path. The power circuit breaker is characterized in that secondary electrodes are additionally provided, which protrude into the vicinity of the switching path and are designed and arranged in such a way that arcs can be produced (a) between the main electrodes and the secondary electrodes and (b) between the individual secondary electrodes during the switching process. The power circuit breaker according to the invention can be advantageously used in vehicles and in ultra-high-voltage AC and HVDC (high-voltage direct current) transmission systems and causes arcs to be extinguished as early as possible during the switching process.

Abstract: The present invention relates to a method and a suitable apparatus for determining the state of a rechargeable battery and for checking contact resistances in a battery system. According to the invention, an impedance curve is determined using signals at different frequencies and a value for an area, which results from the impedance curve, is then calculated from a predetermined threshold value and an x axis. The value for the area is a measure of the ageing of the battery. A control signal is generated on the basis thereof. In one preferred embodiment, said control signal is used to drive a signaling apparatus and thus to present the state of the battery to a user. The present invention can be used, for example, in motor vehicles that are electrically driven.

Abstract: The invention relates to a medical diagnostic device (1) having at least one sensor matrix (2) for capturing electrical voltage signals at a plurality of locations on the body surface of a person or animal, wherein the diagnostic device (1) is set up for capturing a signal (12) representing the position of the sensor matrix (2) relative to the body of the person or animal, and for determining position information (14) about the position of the sensor matrix (2) relative to the body, localized image information (13) is determined from the voltage signals, and the localized image information (13) is associated with the position information (14).

Abstract: A method of manufacturing of a semi-conductor element, comprising the following steps: providing a substrate, the substrate having a surface, the surface being partially coated with a coating and having at least one uncoated area, and growing a truncated pyramid of gallium nitride on the uncoated area, wherein the method comprises the following step: growing at least one gallium nitride column on the truncated pyramid.

Abstract: The subject of the present invention is an anti-ricin antibody and the use thereof for the treatment of an individual suffering from ricin poisoning.

Abstract: The invention relates to a pharmaceutical composition with a content in active ingredient that can be an antimycotic, so that the composition is suitable for the treatment of onychomycoses, in particular severe onychomycoses. The inventive formulation is an ointment-like thermogel at body temperature and an inviscid thermogel at lower temperatures and facilitates the permeation of sufficient active ingredient quantities through human fingernails and toenails, in order to also treat severe onychomycoses.

Abstract: A multi-layer capacitor includes several electrically insulating layers that are stacked on top of one another. Parallel electrode plates are arranged between the insulating layers alternately one on top of the other, with each of the plates being separated by an intervening insulating layer. At least one first connecting line which extends perpendicularly through the layers is connected to one set of electrode plates and is insulated in relation to the other set of second electrode plates. Similarly, second connecting lines extend perpendicularly through the layers and are connected to the other set of plates and are insulated in relation to the one set of plates. The first connecting line extends centrally through the stacked electrode plates and is designed to carry a high-frequency signal.

Abstract: A multichip circuit module includes a main board, at least one carrier substrate mounted on and in electrical contact with the main board, and at least one semiconductor chip arranged on the carrier substrate and in electrical contact therewith. The carrier substrate has at least one cavity on an assembly surface for receiving the semiconductor chip. The cavity includes connecting contacts which join with associated bumps on the semiconductor chip using a flip-chip technique. The assembly surface of the carrier substrate is placed on a contact surface of the main board, and a filling material is provided between the contract surface of the main board and the assembly surface of the carrier substrate.

Abstract: An optical component for effecting frequency selective reflection in the gigahertz and terahertz frequency ranges and for effecting wave permeability includes at least one first layer (1, 3, 5) made of a first material (m1). The first material is optically permeable to electromagnetic radiation of a reference frequency (f) between 5 gigahertz (GHz) and 10 terahertz (THz) and has a first refractive index (n1) and an optical thickness of approximately one-fourth the wavelength (?) of the electromagnetic radiation of the reference frequency (f) in the first material (m1).

Abstract: A two-layered anode (1?) has a lower layer (2) including a non-conductive carrier material to which a conductive electrode layer (3?) is applied. Non-conductive areas, formed by partial removal of the electrode layer, have a predetermined structure corresponding to the structure of a structured polymer film (11) to be formed. The anode (1?) is connected with a platinum cathode in an electrolyte into which compounds of low molecular weight, preferably monomers of the polymer film (11), are introduced. During current flow, a conductive polymer film (11) of the predetermined structure is formed on conductive areas brought into contact with the electrolyte. A non-conductive substrate layer (13) is applied to the structured polymer film (11). The structured polymer film (11) adheres to the non-conductive substrate layer (13) and can be released from the electrode (1?) without damaging the electrode.

Abstract: Complex distributed systems with basic components (B) which have data processing program modules and/or electronic circuit modules that exchange data with each other have their timing behavior analyzed based on the timing behavior of individual basic components (B) and transformation functions derived from event model classes.

Abstract: An apparatus for determining the properties of a material, that is to be examined, by applying a swept-frequency high frequency signal and measuring a reflection factor of the resonance signal. The apparatus has a microwave supply conductor for feeding the high frequency signal, a sensor waveguide that is coupled to the microwave supply conductor, a helical conductor that is arranged inside the sensor waveguide, and an intermediate layer between a first end of the sensor waveguide and the helical conductor. Typically, the sensor waveguide is cylindrical and the helical conductor is supported centrally therein along the longitudinal axis of the sensor waveguide by a support that is part of the intermediate layer. A coupling layer is provided between the helical conductor and the material to be examined in the region of a second end face of the sensor waveguide.

Abstract: A two-layered anode (1′) is used for the electrochemical polymerisation. The lower layer (2) consists of a non-conductive carrier material to which a conductive electrode layer (3′) is applied, the electrode layer being removed in part-areas in order to form non-conductive areas. the non-conductive areas have a predetermined structure which corresponds to the structure of the structured polymer film (11) to be formed. the anode (1′) is held together with a platinum cathode in an electrolyte into which compounds of low molecular weight, preferably monomers of the polymer film (11) to be formed, are introduced. A current flow is produced through the electrolyte via the anode (1′) and cathode. In the course of this a conductive polymer film (11) of the predetermined structure is formed on the conductive areas which are brought into contact with the electrolyte.