Abstract: [Problem] To suppress the onset of adverse effects of drugs that cause gastric ulcers as an adverse effect. [Solution] The onset of gastric ulcers induced by a drug is suppressed by incorporating, into a pharmaceutical composition containing a drug having gastric ulcers as an adverse effect, a high-molecular polysaccharide that has a molecular weight of 800,000-3,000,000 and that produces a gel when a 0.3% aqueous solution thereof is added dropwise to artificial gastric juice.
Abstract: Methods and compositions of treating a subject for cancer pain are provided. In the subject methods, a subject is treated for cancer pain by administering to the subject an effective amount of a narcotic emulsion, e.g., fentanyl elmulsion, formulation. In certain embodiments, the emulsion formulations include a narcotic active agent, oil, water and a surfactant. Also provided are methods of making the subject emulsion formulations as well as kits that include the emulsion formulations.
Type:
Grant
Filed:
September 22, 2014
Date of Patent:
August 30, 2016
Assignees:
Teikoku Pharma USA, Inc., Techno Guard Co., Ltd.
Abstract: Pyrazolone derivative formulations are provided. The formulations include a pyrazolone derivative active agent, e.g., edaravone, and an amphiphilic solubilizing agent. Also provided are methods of making and using the subject formulations.
Type:
Grant
Filed:
November 18, 2009
Date of Patent:
April 14, 2015
Assignees:
Teikoku Pharma USA, Inc., Techno Guard Co., Ltd.
Abstract: Methods and compositions of treating a subject for cancer pain are provided. In the subject methods, a subject is treated for cancer pain by administering to the subject an effective amount of a narcotic emulsion, e.g., fentanyl elmulsion, formulation. In certain embodiments, the emulsion formulations include a narcotic active agent, oil, water and a surfactant. Also provided are methods of making the subject emulsion formulations as well as kits that include the emulsion formulations.
Type:
Grant
Filed:
January 11, 2010
Date of Patent:
October 28, 2014
Assignees:
Teikoku Pharma USA, Inc., Techno Guard Co., Ltd.
Abstract: Pyrazolone derivative emulsion formulations are provided. The emulsion formulations include a pyrazolone derivative active agent, e.g., Edaravone, oil, water and an emulsifier. Also provided are methods of making and using the subject emulsion formulations.
Type:
Grant
Filed:
November 7, 2008
Date of Patent:
May 1, 2012
Assignees:
Teikoku Pharma USA, Inc., Techno Guard Co., Ltd.