Patents Assigned to Technological University Dublin
  • Method for identification of low grade cervical cytology cases likely to progress to high grade/cancer
    Patent number: 11092550
    Abstract: The present invention provides a method of using Raman spectroscopy for identification of low grade cervical cytology cases likely to progress to high grade/cancer. The Applicant has found that high quality Raman spectra can be successfully acquired from morphologically normal appearing cells from negative, LSIL and HSIL Thinprep® specimens and different grades of cervical pre-cancer can be separated with good sensitivities and specificities. Raman spectroscopy can further identify different categories of the LSIL cases i.e., whether they are likely to regress to negative or progress to HSIL cytology.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: August 17, 2021
    Assignees: Technological University Dublin, The Provost, Fellows, Foundation Scholars, and the Other Members of Board, of the College of the Holy and Undivided Trinity of Queen Elizabeth Near Dublin
    Inventors: Shiyamala Duraipandian, Fiona Lyng, Damien Traynor, John O'Leary, Cara Martin, Padraig Kearney
  • Prediction of therapeutic response using vibrational spectroscopy
    Patent number: 10725017
    Abstract: The invention relates to a prognostic method of analyzing a biological sample from a cancer patient to predict his/her response to a specified modality of cancer treatment comprising the steps of: (a) performing spectroscopy on the biological sample to obtain a spectrum; (b) comparing the obtained spectrum with one or more spectra to calculate a probability of a response to the specified modality of cancer treatment by the cancer patient.
    Type: Grant
    Filed: December 20, 2016
    Date of Patent: July 28, 2020
    Assignee: Technological University Dublin
    Inventors: Fiona Lyng, Adrian Maguire, Aidan Meade, Isabel Vega Carrascal, Lisa White, Orla Howe
  • A METHOD FOR IDENTIFICATION OF LOW GRADE CERVICAL CYTOLOGY CASES LIKELY TO PROGRESS TO HIGH GRADE/CANCER
    Publication number: 20200116638
    Abstract: The present invention provides a method of using Raman spectroscopy for identification of low grade cervical cytology cases likely to progress to high grade/cancer. The Applicant has found that high quality Raman spectra can be successfully acquired from morphologically normal appearing cells from negative, LSIL and HSIL Thinprep® specimens and different grades of cervical pre-cancer can be separated with good sensitivities and specificities. Raman spectroscopy can further identify different categories of the LSIL cases i.e., whether they are likely to regress to negative or progress to HSIL cytology.
    Type: Application
    Filed: December 20, 2017
    Publication date: April 16, 2020
    Applicants: Technological University Dublin, The Provost, Fellows and Scholars of the College of the Holy and Undivided Trinity of Queen Elizabet
    Inventors: Shiyamala DURAIPANDIAN, Fiona Lyng, Damien Traynor, John O'Leary, Cara Martin, Padraig Kearney
  • Method for forming a multi-layer anodic coating
    Patent number: 10309029
    Abstract: A method for producing a multi-layer anodic coating on a metal is described. The method comprises the steps of (i) placing the metal in a first electrolytic solution and applying a current to form a first anodic layer having a barrier region; (ii) reducing the applied current to cause a reduction in thickness of the barrier region; and (iii) placing the metal in a second electrolytic solution and applying a current to form a second anodic layer.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: June 4, 2019
    Assignee: Technological University Dublin
    Inventors: Brendan Duffy, Michael Whelan